A river flowing through a forested area with autumn foliage.

Find 5 Star Hotels in Mebane, NC from $99

Check availability on Mebane 5 Star Hotels

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Aug 30 - Aug 31
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Aug 31 - Sep 1
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Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

Our top choices for Mebane 5-star hotels

A modern hotel with a flat roof, large windows, and a covered entrance.
A hotel dining area with tables and chairs, a kitchen in the background, and a large window.
A reception desk with two counters, a map wall, pendant lights, and a ceiling with wooden slats.
A gym with treadmills, elliptical machines, and a large mural on the wall.

1. La Quinta Inn & Suites by Wyndham Mebane

La Quinta Inn & Suites by Wyndham Mebane
Mebane
United States
Delly
$93 nightly
$104 total
Sep 2 - Sep 3
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Mebane
A hotel entrance with a covered walkway, large columns, and potted plants.
A hotel room with a kitchenette, a bed, a sofa, a desk, and a television.
A spacious lobby with a high ceiling, a seating area with sofas and chairs, and a wall with a gear-themed mural.
A hotel with a covered entrance, a sign for a Holiday Inn Express, and a clear blue sky.

2. Holiday Inn Express Hotel & Suites Mebane by IHG

Holiday Inn Express Hotel & Suites Mebane by IHG
Mebane
United States
Brad
$105 nightly
$118 total
Sep 13 - Sep 14
Total with taxes and fees
Holiday Inn Express Hotel & Suites Mebane by IHG
A Marriott Fairfield hotel with a modern facade, large windows, and a well-lit entrance.
A modern living room with a stone fireplace, leather armchair, blue sofa, and round coffee table.
An outdoor patio with wicker furniture and a fire feature, adjacent to a building with large windows and a covered walkway.
A gym with cardio equipment, weight machines, and exercise balls.

3. Fairfield Inn & Suites by Marriott Mebane

Fairfield Inn & Suites by Marriott Mebane
Mebane
United States
Nikki
$125 nightly
$141 total
Sep 6 - Sep 7
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mebane
A Hampton Inn hotel with a modern design, a welcoming entrance, and a well-maintained lawn.
A modern lobby with a seating area, a reception desk, and a patterned rug.

4. Hampton Inn Mebane

Hampton Inn Mebane
Mebane
United States
Joyce
$110 nightly
$124 total
Sep 10 - Sep 11
Total with taxes and fees
Hampton Inn Mebane
A modern hotel with a flat roof, multiple windows, and a covered entrance.
A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher.
A modern hotel lobby with hexagonal pendant lights, a flat-screen TV, a fireplace, and a mix of blue and plaid upholstered chairs.
A modern interior with a blue wall, green wall with plants, red and patterned chairs, and hanging light fixtures.

5. Hawthorn Extended Stay by Wyndham Mebane

Hawthorn Extended Stay by Wyndham Mebane
Mebane
United States
Lou Ann
$115 nightly
$130 total
Aug 31 - Sep 1
Total with taxes and fees
Hawthorn Extended Stay by Wyndham Mebane
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mebane.
JB Duke Hotel

JB Duke Hotel

230 Science Drive Durham NC
$149 nightly
$169 total
Aug 31 - Sep 1
Total with taxes and fees
9.4/10 Exceptional! (694 reviews)
JB Duke Hotel
DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham

2515 Meridian Pkwy Durham NC
$87 nightly
$99 total
Sep 13 - Sep 14
Total with taxes and fees
9.2/10 Wonderful! (1,005 reviews)
DoubleTree Suites by Hilton Raleigh - Durham
The Durham Hotel

The Durham Hotel

315 East Chapel Hill Street Durham NC
$183 nightly
$208 total
Sep 8 - Sep 9
Total with taxes and fees
The Durham Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mebane

This charming small town boasts the Tanger Outlets where savvy shoppers find designer deals without the big-city crowds. Stroll through the historic downtown for local eateries, the Clay Street Mural, and weekend festivals where locals welcome visitors with genuine Southern hospitality.

See all hotels in Mebane
A tree-lined path with autumn leaves, a speed limit sign, and a no trespassing sign.

Top Mebane Hotel Reviews

Find out more about Mebane

Ready for an incredible adventure? Add further enjoyment on your next trip to Mebane by treating yourself to the best of the best when it comes to accommodation. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Mebane so popular in the last year. There's no reason to delay a getaway to Mebane any longer. Besides, the hotels in this area are known for guest services, so you know you'll be looked after during your getaway. Our 5-star hotels in Mebane are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about.

5-Star Hotels in Mebane

Don't be afraid to live the high life while you're on vacation, along with the best conditions. Exceptional service, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A reflexology treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A deep-tissue massage to help your cares fall away? Don't want to take our word for it? Plenty of visitors recommend this location.

You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mebane are the perfect place to rest up after a busy day.

Your Getaway Starts Today

The results are in, and Mebane 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Choose one of the 5-star hotels in Mebane today and settle down in the lap of luxury at your convenience.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Mebane?
The amount you pay for a 5-star hotel in Mebane can vary according to when you want to travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to find the best deal on an indulgent stay.
  • Search for the lowest price per night from $99
What makes a hotel 5 stars in Mebane?
From gourmet dining venues and 24/7 fitness centers to pools and superior bedding, the 5-star experience in Mebane is all about luxury and relaxation. But it takes more than just upscale conveniences to earn a 5-star rating. Accommodations must also deliver outstanding guest-focused services like in-room beauty treatments, on-site laundry and concierge services.
Are there any 5-star all-inclusive resorts in Mebane?
Find an indulgent getaway that includes your lodging, food, activities and entertainment in Mebane with our handy filter tool. Search for hotels with a 5-star rating and select the "All inclusive" filter. Have a look at what's included in the purchase price. This way, you can take full advantage of the many perks on offer when you arrive.

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