Photo by Alejandro Ferrari

Find 5 Star Hotels in San Isidro from $75

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Compare San Isidro 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Alvear Palace Hotel

5.0 star property
Recoleta
9.6 out of 10, Exceptional, (913)
"Great stay!"
United States
alain
$510 nightly
The price is $513
Dec 12 - Dec 13
Alvear Palace Hotel

NH City Buenos Aires

5.0 star property
El Centro
8.4 out of 10, Very Good, (1000)
"Clean and comfortable"
United States
Daniel
$85 nightly
The price is $88
Jan 4 - Jan 5, 2026
NH City Buenos Aires

Palacio Duhau - Park Hyatt Buenos Aires

5.0 star property
Recoleta
9.4 out of 10, Exceptional, (462)
"Excelente Hotel. "
Mexico
Matias
$731 nightly
The price is $734
Dec 16 - Dec 17
Palacio Duhau - Park Hyatt Buenos Aires

Alvear Icon Hotel

5.0 star property
Puerto Madero
9.4 out of 10, Exceptional, (487)
"Great location and facilities "
United States
Oliver
$290 nightly
The price is $293
Dec 12 - Dec 13
Alvear Icon Hotel

Hilton Buenos Aires

5.0 star property
Puerto Madero
9.2 out of 10, Wonderful, (1000)
"Excellent location and facilities, dated room. "
Canada
Darren
$237 nightly
The price is $240
Dec 21 - Dec 22
Hilton Buenos Aires

Faena Hotel Buenos Aires

5.0 star property
Puerto Madero
9.0 out of 10, Wonderful, (472)
"The room decor is "interesting". But, it's a great hotel with an excellent Italian restaurant and a top notch fitness center and spa. I would stay there again for sure."
United States
J Paul
$475 nightly
The price is $478
Dec 16 - Dec 17
Faena Hotel Buenos Aires

Four Seasons Hotel Buenos Aires

5.0 star property
Buenos Aires Central Business District
9.4 out of 10, Exceptional, (280)
"All great !"
United States
DAVID
$795 nightly
The price is $798
Dec 16 - Dec 17
Four Seasons Hotel Buenos Aires

Marriott Buenos Aires Downtown

5.0 star property
El Centro
8.2 out of 10, Very Good, (729)
"Great location, service and food "
United States
Luciana
$215 nightly
The price is $218
Jan 5 - Jan 6, 2026
Marriott Buenos Aires Downtown

Palladio Hotel Buenos Aires - MGallery Collection

5.0 star property
Recoleta
9.8 out of 10, Exceptional, (633)
"Great hotel Easy to walk everywhere "
United States
Luan
$320 nightly
The price is $323
Dec 20 - Dec 21
Palladio Hotel Buenos Aires - MGallery Collection

Park Tower, a Luxury Collection Hotel, Buenos Aires

5.0 star property
El Centro
9.2 out of 10, Wonderful, (452)
"Overall great experience, the staff was great and helpful, the rooms were clean and the breakfast buffet was also quite good. It's well located as well, would definitely recommend."
United States
Michael
$209 nightly
The price is $212
Dec 21 - Dec 22
Park Tower, a Luxury Collection Hotel, Buenos Aires

Alvear Art Hotel

5.0 star property
El Centro
9.4 out of 10, Exceptional, (931)
"Perfect location, great rooms"
United States
Judit
$175 nightly
The price is $178
Dec 12 - Dec 13
Alvear Art Hotel

Claridge Hotel

5.0 star property
El Centro
7.8 out of 10, Good, (1006)
"Older hotel with rooms that could use a bit more love. Good location for exploring different parts of the city."
United States
Susan
$72 nightly
The price is $75
Dec 10 - Dec 11
Claridge Hotel

Casa Lucia Member of Melia Collection

5.0 star property
El Centro
9.6 out of 10, Exceptional, (79)
"Excellent service, professional staff, clean, safe, and beautiful! "
United States
Angela
$323 nightly
The price is $326
Dec 14 - Dec 15
Casa Lucia Member of Melia Collection

NH Collection Buenos Aires Centro Histórico

5.0 star property
El Centro
8.8 out of 10, Excellent, (413)
"Excellent location, clean and spacious room!"
United States
Yvette
$118 nightly
The price is $121
Dec 26 - Dec 27
NH Collection Buenos Aires Centro Histórico

DoubleTree by Hilton Buenos Aires

5.0 star property
El Centro
8.6 out of 10, Excellent, (790)
"Great place to stay near the center of the city. Sundays are slow in the evening as most of the stores and restaurant close"
United States
Virgilio
$139 nightly
The price is $142
Dec 25 - Dec 26
DoubleTree by Hilton Buenos Aires

Recoleta Grand, a Tribute Portfolio Hotel

5.0 star property
Recoleta
9.0 out of 10, Wonderful, (650)
"Great hotel will definitely comeback "
United Kingdom
Sebastian
$320 nightly
The price is $323
Dec 10 - Dec 11
Recoleta Grand, a Tribute Portfolio Hotel

Emperador Hotel Buenos Aires

5.0 star property
El Centro
8.8 out of 10, Excellent, (471)
"Is a very centralized location with easy access to Palermo, Puerto Madero, and la Recoleta!"
United States
carlos
$264 nightly
The price is $267
Dec 23 - Dec 24
Emperador Hotel Buenos Aires

AQ Tailored Suites

5.0 star property
Recoleta
9.6 out of 10, Exceptional, (550)
"We loved the hotel and its location!!!"
United States
Ana Rosa
$237 nightly
The price is $240
Jan 9 - Jan 10, 2026
AQ Tailored Suites

Soho Point Central

5.0 star property
Palermo
8.6 out of 10, Excellent, (61)
"Really great property and location with welcoming and helpful staff. Nice living area and two bedrooms with comfortable beds. Highly recommend!"
United States
Eleonora
$73 nightly
The price is $76
Dec 10 - Dec 11
Soho Point Central

Sofitel Buenos Aires Recoleta

5.0 star property
Buenos Aires Central Business District
9.2 out of 10, Wonderful, (600)
"We got an upgrade to a Prestige Suite from a Junior Suite at checkin by mentioning that we are a Expedia Gold member . Beautiful 5 Star Hotel on the bay . Concierge Martin was very helpful . Bed very comfortable. Close to the AEP airport . "
United States
Mart
$218 nightly
The price is $221
Jan 1 - Jan 2, 2026
Sofitel Buenos Aires Recoleta
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about San Isidro

Discover the historic Hippodrome where horse racing traditions come alive alongside the vibrant weekend craft market. Explore the grand Cathedral of San Isidro and relax in Plaza Mitre where locals gather for mate tea beneath jacaranda trees.

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Photo by Alejandro Ferrari
Open Photo by Alejandro Ferrari

Top San Isidro Hotel Reviews

Find out more about San Isidro

You enjoy the finer things in life, both at home and on vacation. Pamper your every desire on your impending getaway. There's no reason to delay a getaway to San Isidro any longer. You'll join the multitudes of vacationers who have made San Isidro so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in San Isidro and get ready to enjoy the getaway of a lifetime.

5-Star Hotels in San Isidro

You'll have a fantastic time at one of these 5-star hotels. Exceptional customer care, spacious rooms, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. How do you want to relax? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A body scrub that will leave you feeling great? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs.

Yearning for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in San Isidro are waiting for you to relax after a busy day.

Make Your Escape

The results are in, and San Isidro 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Opt for one of our San Isidro 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in San Isidro?
There are many different pricing options for 5-star hotels in San Isidro on Expedia. How much you'll pay will depend on when you plan to travel, trip length and other factors. Compare available accommodations for your desired dates and use our pricing and other filters to find the ideal upscale stay.

  • Search for the lowest price per night from $85

What makes a hotel 5 stars in San Isidro?
Flawless guest service characterizes every 5-star hotel in San Isidro. From the moment you arrive, staff attend to your every whim, whether offering luggage assistance and storage or providing a nightly turn-down service. On top of that, hotels must feature superior amenities to obtain a 5-star rating. These can include luxury bath products, a wellness center, swimming pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in San Isidro?
Use our handy filters to find an upscale retreat in San Isidro where most of what you need is included in the price. From there, narrow your results for resorts that have a 5-star rating and are categorized as "All inclusive." The most important thing on the to-do list at these stays? Relaxation and enjoyment.

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