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A cathedral with a tall spire, surrounded by a mix of residential and commercial buildings, with a clear sky above.

Find 5 Star Hotels in San Isidro from $73

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Check prices for these dates, December 12 – 13, 2026

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Our top choices for San Isidro 5-star hotels

1. Alvear Palace Hotel

A large, historic hotel with multiple floors and a classic architectural style.

Location: Recoleta
Guest rating: 9.6/10 (Exceptional, 1003 reviews)
Price: $485 nightly, $488 total, Nov 13 - Nov 14, for Our top choices for San Isidro 5-star hotels
Review: Lovely hotel, by William

2. Hilton Buenos Aires

A modern building with a glass facade, a central atrium, and a car parked in front.

Location: Puerto Madero
Guest rating: 9.4/10 (Exceptional, 1000 reviews)
Price: $221 nightly, $224 total, Dec 5 - Dec 6, for Our top choices for San Isidro 5-star hotels
Review: Great stay, by JORGE

3. Sofitel Buenos Aires Recoleta

A bar area with shelves of liquor bottles and glasses.

Location: Buenos Aires Central Business District
Guest rating: 9.4/10 (Exceptional, 727 reviews)
Price: $259 nightly, $262 total, Dec 6 - Dec 7, for Our top choices for San Isidro 5-star hotels
Review: Great location, very comfortable rooms, by paola

4. Sheraton Buenos Aires Hotel and Convention Center

A room with a city view, large windows, and a table with a plant and a small table.

Location: El Centro
Guest rating: 8.2/10 (Very good, 1001 reviews)
Price: $179 nightly, $182 total, Nov 20 - Nov 21, for Our top choices for San Isidro 5-star hotels
Review: Great hotel!, by Victoria

5. Palacio Duhau - Park Hyatt Buenos Aires

A grand hotel with multiple floors, outdoor dining areas, and a well-maintained garden.

Location: Recoleta
Guest rating: 9.4/10 (Exceptional, 531 reviews)
Price: $640 nightly, $643 total, Nov 23 - Nov 24, for Our top choices for San Isidro 5-star hotels
Review: Staff was exceptional, the butler service and tour was great., by Leon

6. Four Seasons Hotel Buenos Aires

A grand hotel with a glass conservatory, classical architecture, and a well-lit entrance.

Location: Buenos Aires Central Business District
Guest rating: 9.6/10 (Exceptional, 357 reviews)
Price: $900 nightly, $903 total, Nov 23 - Nov 24, for Our top choices for San Isidro 5-star hotels
Review: Great stay.. lovely staff!! Definitely recommend, by Aadhar

7. Casa Lucia Member of Melia Collection

A breakfast buffet with various food items and a large window with a view of a building.

Location: El Centro
Guest rating: 9.8/10 (Exceptional, 259 reviews)
Price: $287 nightly, $290 total, Dec 13 - Dec 14, for Our top choices for San Isidro 5-star hotels
Review: Amazing hotel with good location!, by joyce

8. Marriott Buenos Aires Downtown

A modern rooftop lounge with a city view, featuring a sofa, chairs, and a dining area.

Location: El Centro
Guest rating: 8.4/10 (Very good, 817 reviews)
Price: $215 nightly, $218 total, Dec 12 - Dec 13, for Our top choices for San Isidro 5-star hotels
Review: The breakfast was delicious and lots of choices. The staff was for friendly and very caring., by Ayinson

9. Palladio Hotel Buenos Aires - MGallery Collection

Location: Recoleta
Guest rating: 9.8/10 (Exceptional, 814 reviews)
Price: $365 nightly, $368 total, Nov 27 - Nov 28, for Our top choices for San Isidro 5-star hotels
Review: Clean room, great location, friendly staff, by Xiaoqi

10. Alvear Icon Hotel

A modern interior with large windows, a high ceiling, and a view of the water outside.

Location: Puerto Madero
Guest rating: 9.6/10 (Exceptional, 662 reviews)
Price: $379 nightly, $382 total, Dec 13 - Dec 14, for Our top choices for San Isidro 5-star hotels
Review: Fantastic hotel! In every sense, they could improve their food a bit in the bar downstairs but it’s not bad at all. Over all great experience., by Sebastian

11. Alvear Art Hotel

A spacious lobby with a polished marble floor, leather sofas, and a large painting on the wall.

Location: El Centro
Guest rating: 9.4/10 (Exceptional, 1003 reviews)
Price: $273 nightly, $276 total, Dec 13 - Dec 14, for Our top choices for San Isidro 5-star hotels
Review: Prime location, well kept building, rooms are big and clean. The staff super friendly. The breakfast is great., by PAULA

12. Park Tower, a Luxury Collection Hotel, Buenos Aires

A hotel entrance with a glass canopy, a sign reading "PARK TOWER", and a landscaped area with grass and flowers.

Location: El Centro
Guest rating: 9.2/10 (Wonderful, 505 reviews)
Price: $230 nightly, $233 total, Nov 27 - Nov 28, for Our top choices for San Isidro 5-star hotels
Review: Great place to stay. The room was very comfortable., by Mauricio

13. Claridge Hotel

The Claridge Hotel facade with classical architecture, including columns and a grand entrance.

Location: El Centro
Guest rating: 7.8/10 (Good, 1003 reviews)
Price: $71 nightly, $74 total, Dec 7 - Dec 8, for Our top choices for San Isidro 5-star hotels
Review: A Classic hotel with old world charm, by SHERYL

14. SLS Buenos Aires Puerto Madero

A modern sauna with wooden slats, a wooden bench, a bowl with sticks, and towels.

Location: Puerto Madero
Guest rating: 9.6/10 (Exceptional, 405 reviews)
Price: $300 nightly, $303 total, Nov 24 - Nov 25, for Our top choices for San Isidro 5-star hotels
Review: Staff was amazing and excellent hotel, by Chris

15. Faena Hotel Buenos Aires

A fountain with a crown-like structure in a pool.

Location: Puerto Madero
Guest rating: 9/10 (Wonderful, 558 reviews)
Price: $475 nightly, $478 total, Dec 13 - Dec 14, for Our top choices for San Isidro 5-star hotels
Review: Excelente todo, by Vincent

16. Recoleta Grand, a Tribute Portfolio Hotel

A building with a classical facade, large windows, and decorative iron railings.

Location: Recoleta
Guest rating: 9/10 (Wonderful, 716 reviews)
Price: $340 nightly, $343 total, Dec 7 - Dec 8, for Our top choices for San Isidro 5-star hotels
Review: Very nice place to stay in Recoleta. Clean and centric location., by Luis

17. NH Collection Buenos Aires Centro Histórico

A modern hotel room with a large bed, a TV, and a city view.

Location: El Centro
Guest rating: 8.8/10 (Excellent, 471 reviews)
Price: $159 nightly, $162 total, Dec 11 - Dec 12, for Our top choices for San Isidro 5-star hotels
Review: I love the location and the staff was very helpful., by Manuel

18. DoubleTree by Hilton Buenos Aires

A hotel room with a bed, bedside table, lamp, coffee maker, and a bowl of apples.

Location: El Centro
Guest rating: 8.6/10 (Excellent, 876 reviews)
Price: $138 nightly, $141 total, Dec 13 - Dec 14, for Our top choices for San Isidro 5-star hotels
Review: Great location close to all sites, by Timea

19. Emperador Hotel Buenos Aires

A buffet with various food items and a plant in the background.

Location: El Centro
Guest rating: 8.8/10 (Excellent, 525 reviews)
Price: $254 nightly, $257 total, Nov 13 - Nov 14, for Our top choices for San Isidro 5-star hotels
Review: Great staff, by TERRI

20. AQ Tailored Suites

A modern building with a glass facade, a visible staircase, and a sign for 'Tailored Suites'.

Location: Recoleta
Guest rating: 9.6/10 (Exceptional, 646 reviews)
Price: $287 nightly, $290 total, Dec 1 - Dec 2, for Our top choices for San Isidro 5-star hotels
Review: Room was great,very quiet and the breakfast was excellent.The staff couldn’t do more for you, we would stay there again, by john

Top San Isidro Hotel Reviews

Live Belgrano Arcos Boutique Apartments

A rooftop pool with a wooden deck, surrounded by tall buildings, and a clear sky.

Location: Belgrano
Review: Excellent place for 1 or 2 Travellers. Located near coffee shops and restaurants. Close to transportation., by ALAN, August 30, 2026, rated 10/10 Excellent

Hilton Buenos Aires

Address: Av Macacha Guemes 351, Buenos Aires, C1106BKG, AR
Location: Puerto Madero
Star rating: 5/5
Guest rating: 9.4/10 (1000 reviews)
Review: Everything about the property is fantastic, the location the staff the architecture and the food, but what stands out the best is the amazing staff, by Juan, September 14, 2021, rated 10/10 Excellent

Trendy Apartments in Palermo Hollywood by BueRentals

A multi-story building with balconies, a ground-level entrance, and a tree in the foreground.

Location: Palermo
Review: Very convenient location., by Eduardo, October 24, 2026, rated 10/10 Excellent

Palladio Hotel Buenos Aires - MGallery Collection

Address: Ave Callao 924, Buenos Aires, Buenos Aires, C1023AAP, AR
Location: Recoleta
Star rating: 5/5
Guest rating: 9.8/10 (814 reviews)
Review: Customer service at the hotel was excellent. Our original room booked wasn’t available when we arrived but Katherine noticed we were unhappy about it, and unprompted upgraded our room for the other days. Rooms were very spacious and new. Clean, nice location across the park and friendly bar staff especially Felix who haves excellent restaurant recommendations. Definitely will come again., by Anonymous traveler, November 14, 2019, rated 10/10 Excellent

Alvear Palace Hotel

Address: Avenida Alvear 1891, Buenos Aires, Capital Federal, 1129, AR
Location: Recoleta
Star rating: 5/5
Guest rating: 9.6/10 (1003 reviews)
Review: An oassis of peace in a calm neighborhood, yet close to all the main activities in Buenos Aires. Great Restaurant with nice French twist., by Anonymous traveler, September 13, 2016, rated 10/10 Excellent

Alvear Icon Hotel

Address: Aime Paine 1130, Buenos Aires, C1107CFB, AR
Location: Puerto Madero
Star rating: 5/5
Guest rating: 9.6/10 (662 reviews)
Review: Great place great service spectacular View great location friendly staff Will win we back, by Anonymous traveler, February 12, 2018, rated 10/10 Excellent

Sofitel Buenos Aires Recoleta

Address: Posadas 1232, Recoleta, Buenos Aires, Capital Federal, C1011ABF, AR
Location: Buenos Aires Central Business District
Star rating: 5/5
Guest rating: 9.4/10 (727 reviews)
Review: Always a pleasure to return to this hotel, it's really a great deal in an area of hyper-expensive hotels., by Denise, November 25, 2017, rated 10/10 Excellent

Palacio Duhau - Park Hyatt Buenos Aires

Address: Av. Alvear 1661, Buenos Aires, Capital Federal, C1014AAD, AR
Location: Recoleta
Star rating: 5/5
Guest rating: 9.4/10 (531 reviews)
Review: The entire staff at the hotel were excellent. Concierge staff were very helpful in planning activities for our trip. Front desk and restaurant staff were excellent too. The hotel is in a great centralized location in Buenos Aires and within a a walking distance to great restaurants, museums, Eva Peron's cemetery and shopping., by Louay, January 2, 2017, rated 10/10 Excellent

Park Tower, a Luxury Collection Hotel, Buenos Aires

Address: Avenida Leandro N Alem 1193, Buenos Aires, Capital Federal, 6032, AR
Location: El Centro
Star rating: 5/5
Guest rating: 9.2/10 (505 reviews)
Review: The Park Tower is a grand hotel. No tour groups. Beautiful lobby. You are checked at a desk, not a counter. Superior service. Assigned butler. Elegantly appointed rooms. It’s a disappearing breed. Even if you want something more informal and casual, as many younger travelers do, you ought to experience a hotel like this once in a while. Finally, as expected, the staff are extremely courteous. I would also say they are genuinely warm and kind. There is not the slightest hint of condescension but..., by Warren H. Nelson, September 16, 2023, rated 10/10 Excellent

Four Seasons Hotel Buenos Aires

Address: Posadas 1086/88, Buenos Aires, Capital Federal, C1011 ABB, AR
Location: Buenos Aires Central Business District
Star rating: 5/5
Guest rating: 9.6/10 (357 reviews)
Review: As we have come to expect from Four Seasons, we were made to feel luxuriously at home from the moment we arrived. Their level of service simply makes everywhere else pale in comparison. Our concierge, Pablo, was the epitome of warmth and professionalism with excellent English!, by Patti, June 14, 2017, rated 10/10 Excellent

AQ Tailored Suites

Address: Montevideo 937, Buenos Aires, C1019, AR
Location: Recoleta
Star rating: 5/5
Guest rating: 9.6/10 (646 reviews)
Review: We enjoyed our stay very much at the property - the front desk staff as well as the breakfast and cleaning crew were friendly, attentive, and happy to help. We appreciated that the desk staff spoke English, as they were able to help us book a show and contact a driver in Spanish. The breakfast is very nicely appointed in a nice area. The hotel is easy walking distance to many places, and easy for pick up by an Uber. Dinner, grocery, cafes and wine stores nearby, as well as short walks to..., by Kimberly, April 4, 2022, rated 10/10 Excellent

Hotel Club Frances

Location: Recoleta
Review: My wife and I booked this hotel through Expedia. No previous knowledge of this hotel (we usually stay at the Four Seasons). We are glad we found it. Excellent rooms (I got an upgrade for being Expedia Gold) and also a complimentary lunch coupon for USD55.- Staff is dedicated, attentive to detail and well trained, both front desk and restaurant. The food at the restaurant is excellent, the restaurant caters to the hotel guests, but get a lot of repetitive business from locals who know about..., by Anonymous traveler, March 30, 2016, rated 10/10 Excellent

Alvear Art Hotel

Address: Suipacha 1036, Buenos Aires, Capital Federal, C1008AAV, AR
Location: El Centro
Star rating: 5/5
Guest rating: 9.4/10 (1003 reviews)
Review: Great location, service, food, and overall comfort. Would definitely return., by Anonymous traveler, April 7, 2018, rated 10/10 Excellent

Faena Hotel Buenos Aires

Address: Martha Salotti 445, Buenos Aires, Capital Federal, C1107BDA, AR
Location: Puerto Madero
Star rating: 5/5
Guest rating: 9/10 (558 reviews)
Review: A, by anuar manzur salomon, May 15, 2023, rated 10/10 Excellent

Algodon Mansion

A spacious living room with a sofa, armchairs, a coffee table, and a bookshelf.

Location: Buenos Aires Central Business District
Review: This does not feel like a hotel, it is more like being in a private home. The staff is extraordinary! No request is too much for them and their demeanor is just so personal, friendly and sincere, it's like you are family to them. The rooms are modern, luxurious and sparkling clean. We spent 6 days upon arrival in Argentina and then our final 2 days prior to departing - everything was wonderful. Both rooms we had were fabulous, my wife loved the fabrics and marble. The only minor complaint in..., by Art, May 7, 2015, rated 10/10 Excellent

Emperador Hotel Buenos Aires

Address: Av Libertador 420, Buenos Aires, Capital Federal, C1001ABR, AR
Location: El Centro
Star rating: 5/5
Guest rating: 8.8/10 (525 reviews)
Review: My wife and I stayed at this hotel for several nights. The hotel staff are extremely helpful and they are bilingual (spanish and english). They were also able to exchange our money for ARG pesos. The rooms were really clean and in really good shape. The hotel has a nice bar and restaurant in the lobby area. The food from the restaurant was good. Breakfast was really good as well. There was a large spread to choose from (eggs, sausage, bacon, cereal, pastries, yogurt, fruit, toast). The pool is..., by Christopher, January 19, 2016, rated 10/10 Excellent

Recoleta Grand, a Tribute Portfolio Hotel

Address: Las Heras 1745, Buenos Aires, Capital Federal, C1018AAB, AR
Location: Recoleta
Star rating: 5/5
Guest rating: 9/10 (716 reviews)
Review: I was in BA mostly for business for 2 weeks, and had a great time at this hotel. The staff was very accommodating and helped me sort out numerous problems (lost luggage, reservation changes, etc.). The room was great and had all the features you'd expect, and the location was quite convenient as well. Most importantly (for me, at least), the wi-fi was incredibly fast compared with other hotels/apartments I've tried in BA. If you go downstairs to get a good signal, you'll get speeds approaching..., by Brian, January 17, 2016, rated 10/10 Excellent

Find out more about San Isidro

You enjoy the finer things in life, both at home and on vacation. Pamper your every desire on your impending getaway. There's no reason to delay a getaway to San Isidro any longer. You'll join the multitudes of vacationers who have made San Isidro so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in San Isidro and get ready to enjoy the getaway of a lifetime.

5-Star Hotels in San Isidro

You'll have a fantastic time at one of these 5-star hotels. Exceptional customer care, spacious rooms, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. How do you want to relax? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A body scrub that will leave you feeling great? Butler services? Whatever it is your heart desires, you're bound to find it here. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs.

Yearning for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in San Isidro are waiting for you to relax after a busy day.

Make Your Escape

The results are in, and San Isidro 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Opt for one of our San Isidro 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Frequently Asked Questions

How much does it cost to stay in a 5-star hotel in San Isidro?

There are many different pricing options for 5-star hotels in San Isidro on Expedia. How much you'll pay will depend on when you plan to travel, trip length and other factors. Compare available accommodations for your desired dates and use our pricing and other filters to find the ideal upscale stay.

Search for the lowest price per night from $73

What makes a hotel 5 stars in San Isidro?

Flawless guest service characterizes every 5-star hotel in San Isidro. From the moment you arrive, staff attend to your every whim, whether offering luggage assistance and storage or providing a nightly turn-down service. On top of that, hotels must feature superior amenities to obtain a 5-star rating. These can include luxury bath products, a wellness center, swimming pools, fine dining restaurants and knowledgeable concierge.

Are there any 5-star all-inclusive resorts in San Isidro?

Use our handy filters to find an upscale retreat in San Isidro where most of what you need is included in the price. From there, narrow your results for resorts that have a 5-star rating and are categorized as "All inclusive." The most important thing on the to-do list at these stays? Relaxation and enjoyment.

Are there any 5-star vacation rentals in San Isidro?

You won't find any 5-star vacation rentals in San Isidro on our site, but there are a range of other top-rated options worth looking into. Browse our vacation rentals in San Isidro to discover the perfect place for your getaway.