Byron Vacations from $792

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Your Byron Vacation

Book a tailored Byron vacation package that includes only the things you need and nothing you don't. Good for bars and pubs, history and culture, think about staying in the neighborhood of Downtown Rochester. There's plenty to put on your must-do list during your trip to Byron, starting with leading attractions such as Oxbow Park and Douglas Trail. A couple of quick clicks is all it takes to put together the ultimate Byron vacation on Expedia.

The Latest Byron vacation packages

Price found within the past 48 hours. Click for updated prices.
Aspen Select
The Towers At Kahler Grand Hotel
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
The Berkman
Holiday Inn Express & Suites Winona by IHG
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Byron Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from May 22 to May 23
$146 total
May 22 - May 23
Total with taxes and fees
8.4/10 Very Good! (2,091 reviews)
Staff was very friendly. Room was meticulously cleaned. Very easy to get to and from my appointments at the Mayo Clinic from the hotel.

Reviewed on May 18, 2026

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from May 19 to May 20
$152 total
May 19 - May 20
Total with taxes and fees
8/10 Very Good! (1,568 reviews)
Well, when we pulled in the parking lot, it’s just an absolutely beautiful place really nice. And when I walked inside, I thought a oh boy my husband and I have hit the jackpot. This is absolutely breathtaking. OK the room was nice. It was tiny, but very nice looking the problems I had were. There ...

Reviewed on May 15, 2026

Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from May 31 to Jun 1
$160 total
May 31 - Jun 1
Total with taxes and fees
9/10 Wonderful! (1,003 reviews)
The room was clean and comfortable. The location was convenient. The only downside was that staff was vacuuming in the hallway at 8pm. We had to get up early for an event.

Reviewed on May 18, 2026

Hyatt House Rochester/Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Byron Vacation Packages

Byron Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Rochester Intl. Airport (RST)
Population
5,300
Top Sights
Rochester Civic Theater, Minnesota Childrens Museum and Cascade Lake Beach

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Frequently asked questions

How much does a Byron vacation package cost?
Offering great value package deals from $792 on Expedia, you'll be thrilled with how little a vacation to Byron costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Byron?
December, January and February are the best times to look for cheap Byron vacation packages. Choosing to travel in less busy months means you'll typically find lower prices on accommodations and flights.
How many days is enough for Byron?
Generally, a handful of days is enough to tick off the main sights during your Byron vacation. However, if you'd like to have more time to unwind or take day trips, consider extending your trip.
How to find the best Byron package deals?
Landing a cheap Byron package deal is a breeze with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget range, add some filters and see what's available. You can tailor your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most pocket-friendly Byron package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Byron vacation as a package?
You can enjoy significant savings on your Byron break by booking a personalized vacation package. Click on the "Package" heading, then enter your destination and travel dates to view the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Byron?
If you have your Byron travel dates finalized, book as soon as you can to bag some incredible deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for setting off on a whim.
Does Expedia offer Book Now, Pay Later Byron vacation packages?
If you're anything like us, you love traveling but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Byron vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.