A mural of Red Wing with a steamship, houses, and a bridge.
Photo by Sara Crotts
Open Photo by Sara Crotts

Southeast Minnesota Adventure Vacations

Book a Hotel + Flight or Car together to unlock savings

Top Adventure vacation packages in Southeast Minnesota

Price found within the past 48 hours. Click for updated prices.
  • A hotel lobby with a reception desk, seating area, and a bar.
    Dec 13 - Dec 17

    Super 8 by Wyndham Rochester Mayo Clinic Area + Flight

    Rochester
    4 nights
    2.0 star property
    7.8/10 - Good (1,003 reviews)
    Roundtrip • Chicago (ORD) - Rochester (RST)
    ORD - RST • Nonstop RST - ORD • Nonstop
    $1,037
    $1,035
    per traveler
    found 1 day ago
    Super 8 by Wyndham Rochester Mayo Clinic Area
  • An indoor swimming pool with a wooden ceiling, clear blue water, and seating areas around the pool.
    Dec 13 - Dec 17

    Med City Inn & Suites - Mayo Clinic Area + Flight

    Kutzky Park
    4 nights
    2.5 star property
    7.8/10 - Good (1,058 reviews)
    Roundtrip • Chicago (ORD) - Rochester (RST)
    ORD - RST • Nonstop RST - ORD • Nonstop
    $1,076
    $1,063
    per traveler
    found 1 day ago
    Med City Inn & Suites - Mayo Clinic Area
  • A spacious outdoor dining area with multiple tables and chairs, large windows, and a wooden ceiling structure.
    Dec 13 - Dec 17

    Hotel Indigo Rochester – Mayo Clinic Area by IHG + Flight

    Downtown Rochester
    4 nights
    3.5 star property
    8.8/10 - Excellent (1,005 reviews)
    Roundtrip • Chicago (CHI) - Rochester (RST)
    ORD - RST • Nonstop RST - ORD • 1 stop
    $1,050
    $1,039
    per traveler
    found 19 hours ago
    Hotel Indigo Rochester – Mayo Clinic Area by IHG
  • An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.
    Dec 13 - Dec 17

    Home2 Suites by Hilton Rochester Mayo Clinic Area + Flight

    Rochester
    4 nights
    3.0 star property
    9.6/10 - Exceptional (1,003 reviews)
    "So very helpful. Love the gym too"
    Reviewed November 10, 2026
    Roundtrip • Chicago (ORD) - Rochester (RST)
    ORD - RST • Nonstop RST - ORD • Nonstop
    $1,222
    $1,222
    per traveler
    found 1 day ago
    Home2 Suites by Hilton Rochester Mayo Clinic Area

Discover the most popular places to visit in Southeast Minnesota

Villa Bellezza

8.4/10 (31 reviews)
You can enjoy a tasting or tour at Villa Bellezza during your travels to Pepin. While you're in the area, stroll along the lakeside.
See properties

What to do in Southeast Minnesota

SEA LIFE at Mall of America

SEA LIFE at Mall of America

$30
per adult
90% of travelers recommend
SEA LIFE at Mall of America
See all activities in Southeast Minnesota

Top Adventure Southeast Minnesota Hotels

A spacious lobby with a staircase, a fireplace, a reception desk, and a seating area.

Willow Inn Suites Rochester

Willow Inn Suites Rochester
2.5 star property
5.2 mi from Southeast Minnesota
6.8 out of 10, (16 reviews)
$70 nightly
The price is $81
Nov 11 - Nov 12
Total with taxes and fees
Willow Inn Suites Rochester
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Southeast Minnesota

Find awesome Southeast Minnesota adventure vacations

How can I book the best Southeast Minnesota adventure trips?

Choose your own adventure in Southeast Minnesota, whether that’s a white-knuckle experience or a weekend walk. Read the reviews of the adventures that have gone before to be sure your chosen stay is your idea of fun.

How can I plan the perfect Southeast Minnesota family adventure vacation?

Adventure awaits when you select the family-friendly filter. There’s plenty of excitement for all ages in Southeast Minnesota. Just make sure to check your chosen escapade is within the realms of can-do for the whole clan and will have the whole team grinning.

Can I book all-inclusive Southeast Minnesota adventure vacation packages?

By refining your filters, you can explore all-amazing, all-adventurous, all-inclusive vacation packages. Amp up the extravagance with a few more filters too. Pick pristine pools, sensational spas, or wondrous waterparks for a sensational adventure getaway.

Why should I book a Southeast Minnesota adventure vacation for couples?

Book a Southeast Minnesota couples adventure vacation for the ultimate in romance and memory-making. Stunning scenery, heart-racing happenings, and the grandeur of the great outdoors—it’s the best way to bond.

How can I find the best deals on adventure packages in Southeast Minnesota?

It’s easy to unleash fabulously affordable adventures. Enter the dates for your caper, then sort your search results by price or deals.

Can I book an adventure vacation package in Southeast Minnesota with free cancellation and/or flexible dates?

Yes! When you’re searching for a great getaway, filter by payment option for free cancellation, so a change of plans won’t mess up your adventures. You’ll find buy now, pay later options, too, for full-on flexibility.

Why should I book a Southeast Minnesota adventure trip with Expedia?

Adventure, airfare, accommodation, ATOL protection, and activities—all on one site. And that’s just the benefits that begin with A.

What types of mountain accommodations are available in Southeast Minnesota?

5-star hotels, cozy mountain lodges, and quaint bed and breakfasts are some of the most popular types of mountain accommodations for your vacation to Southeast Minnesota. Don't forget to use the filters to home in the amenities you'd like to have, too. Maybe it's a spacious suite with a mountain view or a traditional lobby with a fireplace—you'll find it all with Expedia's easy-to-use search wizard and wide choice of accommodation.