Byron Vacation Rentals

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Our top choices for Byron vacation rentals

Valley Cabin

Valley Cabin
Spring Valley
9.2 out of 10, Wonderful, (7 reviews)
"Great property with plenty of outdoor activities. Had fun fishing the stream and exploring the area. Dan is a great host and I will be visiting again."
United States
JAKE I.
$106 nightly
The price is $114
May 8 - May 9
Total with taxes and fees
Valley Cabin

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Rochester
10.0 out of 10, Exceptional, (3 reviews)
"We enjoyed our stay here. Nice location easy to get to things in Rochester. "
United States
Jonathan P.
$406 nightly
The price is $467
May 8 - May 9
Total with taxes and fees
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
Rochester
10.0 out of 10, Exceptional, (8 reviews)
"This property had everything we needed. Super cute and simple decor, comfortable beds and clean. We would stay here again!! "
United States
Anonymous traveler
$382 nightly
The price is $437
May 8 - May 9
Total with taxes and fees
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (411 reviews)
"Great stay"
United States
Kayla
$242 nightly
The price is $279
Jun 1 - Jun 2
Total with taxes and fees
The Berkman

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
East Side Pioneers
9.0 out of 10, Wonderful, (32 reviews)
"It was a great home for our stay! Very comfortable and easily accessible to downtown!"
United States
Daniel M.
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (148 reviews)
"Great place to stay."
United States
Matthew S.
$104 nightly
The price is $120
May 8 - May 9
Total with taxes and fees
Magical Nest Hideaway

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (176 reviews)
"As always excellent staff, clean and comfortable rooms. Great central location. "
Canada
Anita
$161 nightly
The price is $185
May 22 - May 23
Total with taxes and fees
Broadway Plaza, Trademark Collection by Wyndham

The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry

The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry
East Side Pioneers
9.0 out of 10, Wonderful, (14 reviews)
"Great place!"
United States
Jeremiah E.
$230 nightly
The price is $265
May 10 - May 11
Total with taxes and fees
The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Slatterly Park
10.0 out of 10, Exceptional, (25 reviews)
"Host was great! Space was perfect along with the location"
United States
Lynn
$206 nightly
The price is $237
May 14 - May 15
Total with taxes and fees
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Washington
9.8 out of 10, Exceptional, (27 reviews)
"Beautiful and CLEAN, convenient location. Will definitely stay again!"
United States
Melissa W.
$173 nightly
The price is $199
May 18 - May 19
Total with taxes and fees
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Slatterly Park
10.0 out of 10, Exceptional, (21 reviews)
"I love staying in their properties. I always know I am going to be comfortable and have a great stay. "
United States
Carissa W.
$186 nightly
The price is $214
May 10 - May 11
Total with taxes and fees
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.0 out of 10, Wonderful, (15 reviews)
"Everything was perfect, couldn't ask for a better place to stay"
United States
Jason J.
$169 nightly
The price is $195
May 11 - May 12
Total with taxes and fees
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Cozy Suite in Rochester | Free Breakfast + Shared Pool & Hot Tub. Near Mayo Clinic!

Cozy Suite in Rochester | Free Breakfast + Shared Pool & Hot Tub. Near Mayo Clinic!
Rochester
9.4 out of 10, Exceptional, (6 reviews)
"The two room suite was perfect for the four of us."
United States
Judy S.
$247 nightly
The price is $283
Jun 7 - Jun 8
Total with taxes and fees
Cozy Suite in Rochester | Free Breakfast + Shared Pool & Hot Tub. Near Mayo Clinic!

Delightful cabin with AC in Racine

Delightful cabin with AC in Racine
Racine
$209 nightly
The price is $224
May 8 - May 9
Total with taxes and fees
Delightful cabin with AC in Racine

Custom Luxury Rambler in Highland Hills, Rochester

Custom Luxury Rambler in Highland Hills, Rochester
Rochester
10.0 out of 10, Exceptional, (1 review)
"Hi, I gave 5 stars but wanted to give a few tips. Please have extra bedding & pillows available. "
United States
Whitney M.
$524 nightly
The price is $534
May 10 - May 11
Total with taxes and fees
Custom Luxury Rambler in Highland Hills, Rochester

1 mile to Mayo 3 bed on main floor CoveredByFaith

1 mile to Mayo 3 bed on main floor CoveredByFaith
Parkway
9.8 out of 10, Exceptional, (31 reviews)
"Close to the Mayo Clinic, shopping, dining, etc. Great location!"
United States
T. Buck F.
$211 nightly
The price is $243
May 10 - May 11
Total with taxes and fees
1 mile to Mayo 3 bed on main floor CoveredByFaith

2 bedroom apartment in downtown Zumbrota. Sleeps 4-6.

2 bedroom apartment in downtown Zumbrota. Sleeps 4-6.
Zumbrota
10.0 out of 10, Exceptional, (64 reviews)
"This hostess thought about everything and its the only placed to stay that is nice within 30 minutes of where we were and affordable. "
United States
Janelle
$119 nightly
The price is $128
May 18 - May 19
Total with taxes and fees
2 bedroom apartment in downtown Zumbrota. Sleeps 4-6.

1 mile Mayo 2 step entry Encourage Covered ByFaith

1 mile Mayo 2 step entry Encourage Covered ByFaith
Parkway
10.0 out of 10, Exceptional, (1 review)
"Nice little place and close to the Mayo Clinic. It was perfect. "
United States
Philip
$257 nightly
The price is $297
May 24 - May 25
Total with taxes and fees
1 mile Mayo 2 step entry Encourage Covered ByFaith

2 step entry 1 mile to Mayo CoveredByFaith Inspire

2 step entry 1 mile to Mayo CoveredByFaith Inspire
Parkway
10.0 out of 10, Exceptional, (1 review)
" Wet comfortable place to stay. "
United States
Brad T.
$206 nightly
The price is $237
May 10 - May 11
Total with taxes and fees
2 step entry 1 mile to Mayo CoveredByFaith Inspire

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Rochester
10.0 out of 10, Exceptional, (10 reviews)
"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"
United States
Jessica Z.
$231 nightly
The price is $265
May 11 - May 12
Total with taxes and fees
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Byron Hotel Reviews

Find out more about Byron

Everything you need to know about Byron vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Byron vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Byron vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Byron vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Byron. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Byron in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $114 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Byron rentals

At Expedia, we put the best Byron vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Byron rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Byron vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Byron. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Byron?

Yes, we offer vacation rentals in Byron close to Zollman Zoo, or you can go with a more remote option if you want a relaxing stay. Byron is known for its zoo and golf courses. Make sure you have time to check out the bars and parks during your trip.

What's the top vacation rental that Byron has to offer?

Century Cottage-PERFECT for Mayo & downtown visitors!: Visitors like this Byron vacation home rental. It is located in the city center and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Make the most of the selection of games in this rental home to help you unwind.

What’s there to see and do in Byron?

Family-friendly attractions include Zollman Zoo, whereas Oxbow Park is a spot to enjoy the outdoors. While here, Links of Byron Mini Golf and Cheery Meadows Center are other places worth a visit.

What’s a vacation rental in Byron like?

A vacation rental is a private property you can stay in for a few weeks or just a few days in Byron. Vacation rentals offer amenities like laundry facilities and kitchens so your stay will be comfortable. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from public hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family getaway.