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No exact matches found, but these alternatives could be just right
Recommended hotels in Cairo

1. Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.4 out of 10, (296 reviews)
$69 nightly
The price is $76
Nov 15 - Nov 16
Total with taxes and fees

2. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (107 reviews)
$66 nightly
The price is $74
Nov 8 - Nov 9
Total with taxes and fees

3. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (685 reviews)
$59 nightly
The price is $66
Dec 1 - Dec 2
Total with taxes and fees

4. La Center Motel
La Center MotelLa Center
7.8 out of 10, Good, (24 reviews)
$57 nightly
The price is $61
Nov 16 - Nov 17
Total with taxes and fees

5. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (443 reviews)
$66 nightly
The price is $74
Nov 9 - Nov 10
Total with taxes and fees

6. Peaceful secluded cabin located near Horseshoe Lake
Peaceful secluded cabin located near Horseshoe LakeMiller City
9.8 out of 10, Exceptional, (40 reviews)
$190 nightly
The price is $201
Nov 15 - Nov 16
Total with taxes and fees

7. Cozy cabins on beautiful Horseshoe Lake
Cozy cabins on beautiful Horseshoe LakeOlive Branch
9.8 out of 10, Exceptional, (44 reviews)
$122 nightly
The price is $129
Nov 8 - Nov 9
Total with taxes and fees

8. The Rested Duck Mallard Room
The Rested Duck Mallard RoomOlive Branch
9.4 out of 10, Exceptional, (32 reviews)
$122 nightly
The price is $129
Nov 8 - Nov 9
Total with taxes and fees

9. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Peaceful 2-bedroom cabin with AC in welcoming Villa RidgeVilla Ridge
10.0 out of 10, Exceptional, (6 reviews)
$233 nightly
The price is $247
Nov 8 - Nov 9
Total with taxes and fees

10. Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
$271 nightly
The price is $290
Nov 8 - Nov 9
Total with taxes and fees

11. Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
10.0 out of 10, Exceptional, (4 reviews)
$253 nightly
The price is $271
Nov 8 - Nov 9
Total with taxes and fees

12. Charming Home just minutes from Interstate and Mall
Charming Home just minutes from Interstate and MallKevil
10.0 out of 10, Exceptional, (26 reviews)
$169 nightly
The price is $192
Nov 22 - Nov 23
Total with taxes and fees

13. Charming cottage overlooking Lake Acre
Charming cottage overlooking Lake AcreDongola
10.0 out of 10, Exceptional, (107 reviews)
$243 nightly
The price is $258
Dec 1 - Dec 2
Total with taxes and fees

14. Perfect Couples Retreat - firepit
Perfect Couples Retreat - firepitCarlisle County
10.0 out of 10, Exceptional, (1 review)
$166 nightly
The price is $174
Nov 9 - Nov 10
Total with taxes and fees

15. The Roost | Hot Tub, Ponds & Farm Views
The Roost | Hot Tub, Ponds & Farm ViewsCarlisle County
$188 nightly
The price is $197
Nov 11 - Nov 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Cairo
At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.














































