A coastal city skyline with high-rise buildings, palm trees, and a clear sky.

Calidonia Vacations from $961

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Calidonia Vacation

The stress-free way to experience this exciting city is with a custom-made Calidonia vacation package. Base yourself in the neighborhood of Marbella, which is great for cafes, walking and dining or go someplace else — our package deals are all about you. If your trip to Calidonia includes some sightseeing, drop by major attractions such as Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your routine. Tailor your vacation to Calidonia to suit your style of travel, whatever that may look like.

The Latest Calidonia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Dec 21 - Dec 26

    Surfside Beachfront Suites by Playa Caracol Resorts + Flight

    Punta Chame
    5 nights
    3.5 star property
    8.2/10 - Very good (54 reviews)
    "Very good! A bit dusty the furniture and bedding not like mention on listing. Beautiful apartment with walking distance to the beach"
    Reviewed November 5, 2026
    Roundtrip • Trinidad (POS) - Panama City (PTY)
    POS - PTY • Nonstop PTY - POS • Nonstop
    $1,310
    $961
    per traveler
    found 21 hours ago
    Surfside Beachfront Suites by Playa Caracol Resorts
  • Dec 25 - Dec 31

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    6 nights
    4.0 star property
    9.2/10 - Wonderful (1,005 reviews)
    "Beautiful historic hotel with very clean rooms and great wifi. Mini fridge, safe, bathrobes. Free welcome drink. Perfect location!"
    Reviewed November 6, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    Save 100% on your flight
    $4,365
    $2,158
    per traveler
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • Dec 25 - Dec 31

    Megapolis Hotel Panamá + Flight

    San Francisco
    6 nights
    4.5 star property
    8.6/10 - Excellent (1,841 reviews)
    "Shops nearby"
    Reviewed November 6, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    Save 100% on your flight
    $2,760
    $1,533
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Jan 7 - Jan 12

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen Airport
    5 nights
    4.0 star property
    8.6/10 - Excellent (1,813 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,481
    $1,042
    per traveler
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • Dec 25 - Dec 31

    Hotel Riu Plaza Panama + Flight

    Bella Vista
    6 nights
    5.0 star property
    9.0/10 - Wonderful (6,180 reviews)
    "Todo excelente, lo unico que no me gustó fué que me cobraron por el estacionamiento"
    Reviewed November 6, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,928
    $1,409
    per traveler
    found 1 day ago
    Hotel Riu Plaza Panama

Where to stay in Calidonia

Find the best Calidonia areas and neighborhoods for the activities you enjoy most. Learn more about Calidonia
Learn more about Calidonia

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Discover the most popular places to visit in Calidonia

What to do near Calidonia

Calidonia Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.