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Featured Panama City 5 Star Hotels

See all 152 Hotels in Panama City
Trump International Hotel and Tower Panama

Trump International Hotel and Tower Panama

Calle Punta Colon, Punta Pacifica, Panama City
5.0 out of 5.0
4.4 out of 5 (1,024 reviews)
Good hotelRequested ocean view but did not get and had to change rooms
  Nov 8, 2017

$149

$149
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street, Panama City
5.0 out of 5.0
4.4 out of 5 (404 reviews)
City center, very centrally located. Great hotel. Very luxurious. Makes you feel like royalty!
  Nov 16, 2017

$118

$118
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

Km 6 Road to Veracruz, Panama City
5.0 out of 5.0
4.2 out of 5 (282 reviews)
Westin is the way to go.The hotel and the room were clean. The staff was very friendly and we were able to get by with our limited Spanish speaking skills.
  Nov 2, 2017

$173

$173
Bristol Panama

Bristol Panama

Avenida Aquilino de La Guardia, Panama City
5.0 out of 5.0
4.6 out of 5 (389 reviews)
Always good and will always recommend.This hotel with out a doubt is a hidden jewel. It's close to everything the staff is so friendly. I've been coming here very often and cannot think of staying anywhere else.
  Nov 6, 2017

$127

$127
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There's nothing wrong with enjoying the finer things in life. Why not ask for the best during your trip to Panama City? There's no reason to delay a getaway to Panama City any longer. In fact, the sheer number of visitors to Panama City has shot up over the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to enjoy the getaway of a lifetime.

5-Star Hotels in Panama City

You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and personalized service are all at your fingertips. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling outstanding? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A deep-tissue massage to help your cares fall away?

Ready for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Panama City are waiting for you to rest up after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. This is a great time to find 5-star hotel deals in @region! It's time to plan your next great escape. Opt for one of the 5-star hotels in Panama City today and decompress in total tranquility tomorrow.

Recently booked 5 Star Hotels in Panama City

Trump Ocean Club International Hotel and Tower Panama
5.0 out of 5.0
Last booking: 1 hour ago