$45 Car Rental Centerville, SC

These Centerville insights are based on real traveler data from Expedia, aggregated using AI to help you plan your trip. Updated: August 26, 2026.

Reasons to book a car rental in and around Centerville

Renting a car in Centerville provides the freedom and flexibility to explore the village and surrounding areas at your own pace. With a rental vehicle, you can easily manage your luggage and create flexible travel plans, making it ideal for a variety of travelers. For those seeking outdoor experiences, a trip to Lake Hartwell, located 11 miles away, offers beautiful scenery and opportunities for romantic outings. If you're interested in culture, the Anderson County Museum is just 3 miles from Centerville and provides a glimpse into the local history.

Families will appreciate the convenience of visiting the Anderson Recreation Complex, also 3 miles away, where outdoor activities await. Moreover, a rental car allows you to venture to nearby cities like Clemson, 13 miles away, known for its Memorial Stadium and South Carolina Botanical Gardens. Exploring the city of Anderson, which encompasses Centerville, is easy with a car, enabling visits to attractions like NewSpring Church and Sadlers Creek State Park. Overall, having a rental car enhances your travel experience by offering ease in exploring the diverse attractions around Centerville.

Where to stay around Centerville

• Clemson: Located 13 miles from Centerville, Clemson offers a rich cultural experience with its historic college university and stunning scenery. Enjoy outdoor activities at Lake Keowee, perfect for romance or relaxation, or explore the South Carolina Botanical Gardens, great for family outings. For sports enthusiasts, Memorial Stadium is a must-see. Additionally, you'll find delightful dining options, including wineries and restaurants that enhance your stay.
• Anderson: Situated in Anderson, Centerville provides easy access to outdoor adventures and scenic spots. Visit the Anderson County Museum to dive into local history, or spend time at Sadlers Creek State Park, ideal for outdoor enthusiasts seeking adventure. With a variety of nearby restaurants and wineries, you'll have plenty of options to unwind after a day of exploration. The romantic ambiance here makes it a lovely choice for couples.
• Pendleton: Just 9 miles from Centerville, Pendleton is perfect for those seeking outdoor experiences and picturesque landscapes. Explore the historic Woodburn house for a touch of culture, or enjoy the atmosphere at Memorial Stadium. Ashtabula Historic House offers additional cultural insights. Pendleton's proximity to lakes and recreational areas makes it an attractive option for nature lovers, and the local food scene includes charming wineries and restaurants to savor.

10 tips to save on your car rental in and around Centerville

1. Use filters to find the right car: Refine your search by selecting the vehicle type and desired features. Whether you're looking for an SUV for additional space, a convertible for summer drives, or an economy car for budget-friendly travel, use Expedia's filters to find the perfect fit for your journey.
2. Book in advance to help lower costs: Rental prices can vary based on demand, so it's wise to reserve your car well ahead of your trip. By booking early, you’re likely to secure lower rates and enjoy better availability, especially during peak travel seasons.
3. Consider a smaller car for savings: Smaller vehicles are typically less expensive to rent and easier to maneuver in crowded areas. Mid-size rentals strike a good balance between affordability, comfort, and fuel efficiency.
4. Age guidelines: Drivers under 30 may encounter higher deposits or daily surcharges, and certain vehicle categories—such as SUVs or premium models—might not be available. This can also apply to renters over the age of 70. Always verify the age requirements prior to booking.
5. Check fuel policies: Some rentals follow a full-to-full fuel policy, which requires you to return the car with a full tank to avoid additional fees. This is typically the most advantageous option. Others might offer full-to-empty or prepaid fueling arrangements, which are acceptable as well—just ensure you return the vehicle empty in that case.
6. Save on city and airport pickups: Picking up your rental car at airports often incurs a surcharge, but the added convenience may justify the cost.
7. Know your payment options: Most car rental companies only accept credit cards for payment.
8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected expenses and provides peace of mind if something unforeseen occurs during your trip. It's easy to include car rental insurance when making your reservation on Expedia.
9. Consider unlimited mileage: If you plan on taking long road trips, search for rentals that offer unlimited mileage to prevent extra charges.
10. Bring your driver's license and ID: A valid driver's license is necessary to rent a car.

Finding the cheapest car rentals in Centerville

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Centerville into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Centerville and provide you with a list of the cheapest options, with no added fees.

Renting a car in Centerville

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Centerville. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Centerville

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $45.

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

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Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

• Compact car rentals    
• Convertible car rentals    
• Economy car rentals    
• Fullsize car rentals    
• Luxury car rentals
• Midsize car rentals    
• Mini car rentals    
• Minivan rentals    
• Pickup car rentals    
• Premium car rentals
• Sportscar rentals    
• Standard car rentals    
• SUV rentals    
• Van rentals