
$59 Car Rental Port Isabel, TX
Search and Compare from Car Companies in Port Isabel
Featured car rental suppliers
Compare from agencies
Change your mind: penalty-free cancellation on many/select car rentals
Treat yourself: One Key members save 10% or more on over 1 million car rentals
Shop Smart: Compare car suppliers and package your flight, hotel, and car to save
Top Car Deals in Port Isabel
* Price found within the past 6 days. Click for updated prices.
Economy


$59
Midsize


$72
Special


$80
Compact


$80
Standard


$88
Fullsize


$92
Premium


$102
Standard Elite SUV


$149
Luxury Elite Special


$402
Frequently asked questions
Car Rental Information
SUV, Full Size, Economy | |
$59 | |
$72 | |
$80 | |
Airport Transportation | |
Airport Car Rentals |
Finding the cheapest car rentals in Port Isabel
Using our Search Wizard
If the deals that are available on our page do not suit your needs, then enter Port Isabel into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Port Isabel and provide you with a list of the cheapest options, with no added fees.
Renting a car in Port Isabel
Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Port Isabel. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.
Expected prices in Port Isabel
Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $59.
Flexibility & Cancellation
Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.
We all love being rewarded
One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.
Car classes available from Expedia in 2025
The classes of vehicles available will change depending on your chosen location.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- South Padre Island Hotels
- Hotels near Port Isabel Historical Museum
- Hotels near Treasures of the Gulf Museum
- Hotels near Port Isabel Lighthouse
- Hotels near Long Island Village Golf Course
- All-inclusive Resorts in South Padre Island
- Oceanfront Hotels in South Padre Island
- Hotels near Queen Isabella State Fishing Pier
- Hotels near Beach Park at Isla Blanca
- Cheap Hotels in South Padre Island
- Condo Rentals in South Padre Island
- Hotels near Isla Blanca Park
- Hotels near University of Texas Pan American Coastal Studies Laboratory
- Hotels near Isla Blanca Beach
- Luxury Hotels in South Padre Island
- Beach Hotels in South Padre Island
- Pet-friendly Hotels in South Padre Island
- Motels in South Padre Island
- Adults Only Resorts & in South Padre Island
- Hilton Hotels in South Padre Island
- Romantic Hotels in South Padre Island
- Hotels with an Indoor Pool in South Padre Island
- Marriott Hotels & Resorts in South Padre Island
- Family Hotels in South Padre Island
- Hotels with Suites in South Padre Island
- Cottages in South Padre Island
- Honeymoon Resorts & in South Padre Island
- Condo Resorts in South Padre Island
- Hotels with a Lazy River in South Padre Island
- Hotels with a Swim-up Bar in South Padre Island
- Omni Hotels in South Padre Island
- Fishing Resorts & in South Padre Island
- Hotels with Kitchenettes in South Padre Island
- Apartments in South Padre Island
- Waterpark Hotels in South Padre Island
- Hotel Wedding Venues Hotels in South Padre Island
- 5 Star Hotels in South Padre Island
- Hotels with smoking rooms in South Padre Island
- Gay friendly Hotels in South Padre Island
- Hotels with Hot Tubs in South Padre Island
- Hotels with Connecting Rooms in South Padre Island
- Hotels with Balconies in South Padre Island
- Hotels with Free Breakfast in South Padre Island
- Hotels with Bars in South Padre Island
- Golf Hotels in South Padre Island
- Hotels with Restaurants in South Padre Island
- Historic Hotels in South Padre Island
- B&B in South Padre Island
- Cabin Rentals in South Padre Island
- Villas in South Padre Island
- 4 Star Hotels in South Padre Island
- Hotels with Early Check-in in South Padre Island
- Vacation Homes in South Padre Island
- Resorts & Hotels with Spas in South Padre Island
- Red Roof Inn Hotels in South Padre Island
- 3 Star Hotels in South Padre Island
- Hotels with a Pool in South Padre Island
- Extended Stay Hotels in South Padre Island
- Town Houses in South Padre Island
- Hotel with a Concierge Hotels in South Padre Island
- Hotels with Childcare in South Padre Island
- Treehouses in South Padre Island
- Guest Houses in South Padre Island
- Hotels with a View in South Padre Island
- Hotels with a Gym in South Padre Island
- Resorts in South Padre Island
- Hotels with Tennis Courts in South Padre Island
- Hotels with Free Parking in South Padre Island
- Port Isabel Historical Museum
- Treasures of the Gulf Museum
- Port Isabel Lighthouse
- Long Island Village Golf Course
- Beach Park at Isla Blanca
- Queen Isabella State Fishing Pier
- South Padre Island Vacations
- Visit Laguna Heights
- Isla Blanca Park
- University of Texas Pan American Coastal Studies Laboratory
- Visit South Padre Island
- Isla Blanca Beach
- All inclusive Vacation Packages South Padre Island
- Car rentals near Port Isabel Lighthouse
- Car rentals near Long Island Village Golf Course
- Car rentals near Laguna Heights
- Car rentals near Beach Park at Isla Blanca
- Car rentals near South Padre Island
- Luxury Car Rentals near Beach Park at Isla Blanca
- Premium Car Rentals near Beach Park at Isla Blanca
- Luxury Car Rentals in South Padre Island
- Avis Rental Cars in South Padre Island
- Enterprise Rental Cars in South Padre Island
- Sportscar Car Rentals in South Padre Island
- Hertz Rental Cars in South Padre Island
- Budget Rental Cars in South Padre Island
- Convertible Car Rentals in South Padre Island
- Thrifty Car Rental Rental Cars in South Padre Island