Title: Visit Carlisle: 2026 Travel Guide for Carlisle, South Carolina | Expedia.com [Hotels in Carlisle](https://expedia.com/Carlisle-Hotels.d3000455877.Travel-Guide-Hotels)[Vacation Rentals in Carlisle](https://expedia.com/Carlisle-Vacation-Rentals.d3000455877.Travel-Guide-VacationRentals)[Flights to Carlisle](https://expedia.com/Cheap-Flights-To-Carlisle.d3000455877.Travel-Guide-Flights)[Car Rentals in Carlisle](https://expedia.com/Car-Rentals-In-Carlisle.d3000455877.Car-Rental-Guide)[Carlisle Vacation Packages](https://expedia.com/Carlisle.d3000455877.Destination-Travel-Guides) # Carlisle, SC ## Travel Guide ## Visit Carlisle ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_3000455877) - Carlisle Hotel Deals - Vacation Rentals in Carlisle ![A Taste of Southern Comfort](https://images.trvl-media.com/lodging/97000000/96720000/96717300/96717290/553b72e5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### A Taste of Southern Comfort Carlisle SC Stay at this vacation home in Carlisle. Enjoy a fitness center, laundry facilities, and patios. 9.6/10 Exceptional! (4 reviews) Welcome to SC This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening Reviewed on Jun 28, 2025 [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&selected=96717290&PinnedHotelID=96717290&HadPinnedHotel=true®ionId=3000455877) [](https://expedia.com/Hotel-Search?startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&selected=96717290&PinnedHotelID=96717290&HadPinnedHotel=true®ionId=3000455877) ![Days Inn by Wyndham Clinton / Laurens I-26](https://images.trvl-media.com/lodging/1000000/10000/3900/3862/70952b58_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Days Inn by Wyndham Clinton / Laurens I-26 12374 Highway 56 N Clinton SC $68 nightly $76 total Feb 22 - Feb 23 Total with taxes and fees Book a stay at this business-friendly motel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Josh and Ella Savage Park and ... 6.6/10 (422 reviews) The room was clean and comfortable Reviewed on Jan 27, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F22%2F2026&endDate=2%2F23%2F2026&selected=3862&PinnedHotelID=3862&HadPinnedHotel=true®ionId=3000455877) ![Holiday Inn Express & Suites Newberry by IHG](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/ecf8f7be_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites Newberry by IHG 121 Truman Ave Newberry SC $119 nightly $129 total Feb 27 - Feb 28 Total with taxes and fees Book a stay at this business-friendly hotel in Newberry. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ... 8.8/10 Excellent! (651 reviews) Overall it was a great stay and super nice staff. Would have went for 5 stars except: The desk chair, super modern but not for everyone. No back and almost fell off. The bathroom needs upgrading; when you turn on light, it turns on the vent which is annoying and the step over tub can be more modern. ... Reviewed on Feb 10, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F27%2F2026&endDate=2%2F28%2F2026&selected=2803681&PinnedHotelID=2803681&HadPinnedHotel=true®ionId=3000455877) [See all 55 properties in Carlisle](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F19%2F2026&endDate=2%2F20%2F2026®ionId=3000455877) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![A Taste of Southern Comfort](https://images.trvl-media.com/lodging/97000000/96720000/96717300/96717290/553b72e5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### A Taste of Southern Comfort Carlisle SC Stay at this vacation home in Carlisle. Enjoy a fitness center, laundry facilities, and patios. 9.6/10 Exceptional! (4 reviews) Welcome to SC This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening Reviewed on Jun 28, 2025 [](https://expedia.com/Carlisle-Hotels-A-Taste-Of-Southern-Comfort.h96717290.Hotel-Information) ![1800’s Cabin with Hot Tub, Pet Friendly](https://images.trvl-media.com/lodging/92000000/91200000/91195900/91195817/w1168h1307x1y3-c1983f3b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 1800’s Cabin with Hot Tub, Pet Friendly Rock Hill SC Stay at this cabin in Rock Hill. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Historic Brattonsville and Rock Hill Sports & Event ... 9.6/10 Exceptional! (21 reviews) Quaint, relaxing, beautiful scenery, historically a lot of artifacts that depict mid-end of 19th century. As a former teacher and lover of History, really nice treat, and stay. Host/Owner very gracious and prompt. Perfect for visiting Billy Graham Library in Charlotte, NC. Simple yet charming! ... Reviewed on Nov 16, 2025 [](https://expedia.com/Rock-Hill-Hotels-1800s-Cabin-With-Hot-Tub.h91195817.Hotel-Information) ![Large late1800's home within walking distance to Opera House and downtown.](https://images.trvl-media.com/lodging/96000000/95130000/95125900/95125824/6400922f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Large late1800's home within walking distance to Opera House and downtown. Newberry SC Stay at this vacation home in Newberry. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions The Ritz Theater and Main Street Historic District ... 9.8/10 Exceptional! (38 reviews) We had a wonderful time in this beautiful home! We are a group of four friends, getting together for a visit. Though we were only there for one night, we felt so at home, and at peace. The photos don’t do this home justice! It is an amazing home in and of itself, but has been furnished and decorated ... Reviewed on Feb 13, 2026 [](https://expedia.com/Newberry-Hotels-Large-Late1800s-Home-Within-Walking-Distance-To-Opera-House-And-Downtown.h95125824.Hotel-Information) [See all properties in Carlisle](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000455877&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Carlisle hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2026-02-18&endDate=2026-02-19)[Feb 18 - Feb 19](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2026-02-18&endDate=2026-02-19) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2026-02-19&endDate=2026-02-20)[Feb 19 - Feb 20](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2026-02-19&endDate=2026-02-20) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2%2F20%2F2026&endDate=2%2F22%2F2026)[Feb 20 - Feb 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2%2F20%2F2026&endDate=2%2F22%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000455877&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) ## Cities near Carlisle ![sky and clouds sunset landscape over york south carolina](https://images.trvl-media.com/place/7209/e169d0fe-87c0-4252-bdd4-8ab1f4633ccf.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Chester ![architecture and buildings in union south carolina](https://images.trvl-media.com/place/56013/55ab68bf-0682-4a3a-ac49-dcbb669c8866.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Union ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Whitmire Hotels ](https://www.expedia.com/Whitmire-Hotels.d3000456164.Travel-Guide-Hotels) - [Cabin Rentals in Whitmire ](https://www.expedia.com/Whitmire-Cabins.d3000456164-aaCabins.Travel-Guide-Accommodation) - [5 Star Hotels in Whitmire ](https://www.expedia.com/5Star-Whitmire-Hotels.s50-0-d3000456164.Travel-Guide-Filter-Hotels) - 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[Visit Whitmire ](https://www.expedia.com/Whitmire.dx3000456164) - [South Carolina Bottle Museum ](https://www.expedia.com/South-Carolina-Bottle-Museum-Whitmire.d553248621532656796.Vacation-Attraction) - [Rose Hill Plantation State Historic Site ](https://www.expedia.com/Rose-Hill-Plantation-State-Historic-Site-Union.d553248621532656797.Vacation-Attraction) - [Visit Union ](https://www.expedia.com/Union.dx56013) - [Veterans Memorial Park ](https://www.expedia.com/Veterans-Memorial-Park-Union.d553248621565028500.Vacation-Attraction) - [Union Vacations ](https://www.expedia.com/Union.d56013.Destination-Travel-Guides) - [West Towne Plaza ](https://www.expedia.com/West-Towne-Plaza-Union.d553248621565028501.Vacation-Attraction) - [Visit Chester ](https://www.expedia.com/Chester.dx7209) - [Chester Vacations ](https://www.expedia.com/Chester.d7209.Destination-Travel-Guides) - [Cruse Vineyards and Winery ](https://www.expedia.com/Cruse-Vineyards-And-Winery-Chester.d553248621532657253.Vacation-Attraction) - [Chester County Historical Society Museum and Archives ](https://www.expedia.com/Chester-County-Historical-Society-Museum-And-Archives-Chester.d553248621560906806.Vacation-Attraction) - [Olde English District ](https://www.expedia.com/Olde-English-District-Chester.d553248621532657252.Vacation-Attraction) - [Visit Blackstock ](https://www.expedia.com/Blackstock.dx3000353090) - [Enoree River Vineyards and Winery ](https://www.expedia.com/Enoree-River-Vineyards-And-Winery-Newberry.d650065846682705920.Vacation-Attraction) - [Blackstock Vacations ](https://www.expedia.com/Blackstock.d3000353090.Destination-Travel-Guides) - [Visit Pomaria ](https://www.expedia.com/Pomaria.dx3000456053) - [Musgrove Mill State Historic Site ](https://www.expedia.com/Musgrove-Mill-State-Historic-Site-Clinton.d553248621532656795.Vacation-Attraction) - [Visit Cross Anchor ](https://www.expedia.com/Cross-Anchor.dx553248635519281641) - [Visit Kinards ](https://www.expedia.com/Kinards.dx3000455994) - [Visit McConnells ](https://www.expedia.com/McConnells.dx3000456026) - [Visit Joanna ](https://www.expedia.com/Joanna.dx3000455986) - [Car rentals near Whitmire ](https://www.expedia.com/Car-Rentals-In-Whitmire.d3000456164.Car-Rental-Guide) - [Car rentals near Monarch Mill ](https://www.expedia.com/Car-Rentals-In-Monarch-Mill.d553248634999119412.Car-Rental-Guide) - [Car rentals near Union ](https://www.expedia.com/Car-Rentals-In-Union.d56013.Car-Rental-Guide) - [Car rentals in Avis 3901 Quebec St ](https://www.expedia.com/Avis-at-3901-Quebec-St-Denver-Colorado-USA.v56013.Car-Rental-Guide-Location) - [Car rentals near Lockhart ](https://www.expedia.com/Car-Rentals-In-Lockhart.d553248634999092599.Car-Rental-Guide) - [Car rentals near Gayle Mill ](https://www.expedia.com/Car-Rentals-In-Gayle-Mill.d553248634999106066.Car-Rental-Guide) - [Car rentals near Buffalo ](https://www.expedia.com/Car-Rentals-In-Buffalo.d553248634999436658.Car-Rental-Guide) - [Car rentals near Chester ](https://www.expedia.com/Car-Rentals-In-Chester.d7209.Car-Rental-Guide) - [Priceless Car Rental Rental Cars in Chester ](https://www.expedia.com/Priceless-Car-Rental-Car-Rentals-In-Chester.d7209-c1060.Car-Rental-Guide-Suppliers) - 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[Newberry College ](https://expedia.com/Newberry-College-Newberry.d650066027630927872.Vacation-Attraction) - [Newberry Opera House ](https://expedia.com/Newberry-Opera-House-Newberry.d553248621532656685.Vacation-Attraction) - [Rose Hill Plantation State Historic Site ](https://expedia.com/Rose-Hill-Plantation-State-Historic-Site-Union.d553248621532656797.Vacation-Attraction) - [Historic Winnsboro Town Clock ](https://expedia.com/Historic-Winnsboro-Town-Clock-Winnsboro.d6319528.Vacation-Attraction) - [Veterans Memorial Park ](https://expedia.com/Veterans-Memorial-Park-Union.d553248621565028500.Vacation-Attraction) - [Enoree River Vineyards and Winery ](https://expedia.com/Enoree-River-Vineyards-And-Winery-Newberry.d650065846682705920.Vacation-Attraction) - [Olde English District ](https://expedia.com/Olde-English-District-Chester.d553248621532657252.Vacation-Attraction) - [Chester County Historical Society Museum and Archives ](https://expedia.com/Chester-County-Historical-Society-Museum-And-Archives-Chester.d553248621560906806.Vacation-Attraction) - 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