Cartagena Centro Vacations from $1,015

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Cartagena Centro Vacation

From its dining to its shopping and cafes, there are tons of incredible reasons to book a vacation package to Cartagena Centro. When you need to escape from it all, this seaside neighborhood has a spot just for you. Kick off your trip to Cartagena Centro by heading to nearby attractions such as San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Ayala Center. Whatever your dream Cartagena Centro vacation looks like, you can turn it into reality with Expedia.

The Latest Cartagena Centro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Casa Bali Castillo View Private Pool & R

Casa Bali Castillo View Private Pool & R

Pie del Cerro
$1,015
per person
Dec 3 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Cartagena (CTG)
10/10 Exceptional! (1 review)
Excelente ubicación, buenas instalaciones, en la recepción tanto Omar como la recepcionista fueron muy amables en todo momento.

Reviewed on Feb 17, 2026

Luxury Apartment– Private Pool & Rooftop Jacuzzi

Luxury Apartment– Private Pool & Rooftop Jacuzzi

Cartagena Walled City
Save 100% on your flight
$2,027
per person
Dec 14 - Dec 19
found 12 hours ago
Roundtrip flight included
Miami (MIA) to Cartagena (CTG)
No reviews
Decameron Baru - All inclusive

Decameron Baru - All inclusive

Save 100% on your flight
$1,981
per person
Dec 16 - Dec 21
found 7 hours ago
Roundtrip flight included
New York (JFK) to Cartagena (CTG)
7.6/10 Good! (404 reviews)
The property it’s very good

Reviewed on Sep 28, 2026

Hotel Boutique Casa del Coliseo

Hotel Boutique Casa del Coliseo

Cartagena Walled City
Save 100% on your flight
$1,240
per person
Dec 3 - Dec 8
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Cartagena (CTG)
9.4/10 Exceptional! (327 reviews)
It is a charming colonial house, tastefully decorated, with a good breakfast and an excellent location. Unfortunately, we had an unpleasant incident during check-in due to the receptionist’s incompetence, which unfortunately put a damper on our stay at the hotel. In addition all the noise carries into the rooms.

Reviewed on Aug 17, 2026

Ananda Hotel Boutique

Ananda Hotel Boutique

Cartagena Walled City
Save 100% on your flight
$1,631
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Cartagena (CTG)
9.2/10 Wonderful! (474 reviews)
Great Location, beautiful establishment with friendly service

Reviewed on Sep 24, 2026

Where to stay in Cartagena Centro

Find the best Cartagena Centro areas and neighborhoods for the activities you enjoy most. Learn more about Cartagena Centro
A coastal cityscape with a prominent skyscraper, a marina with boats, and historic buildings with red-tiled roofs.

Cartagena Walled City

3 out of top 10 points of interest in this area

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

A coastal cityscape with high-rise buildings along a curved shoreline.

Bocagrande

1 out of top 10 points of interest in this area

Boasting the city's most prominent hotels, this upscale area offers shopping at Plaza Bocagrande and Nao Mall, and is close to the popular Ciudad Amurallada. Enjoy various dining options and easy access to the Transcaribe station.

A coastal town with a prominent church featuring a tall bell tower and a domed roof.

Getsemani

Travelers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.

A man playing a guitar on a colorful street with yellow, blue, and pink buildings.

San Diego

San Diego is known for its ample dining options, and you can make a stop by House of Gabriel Garcia Marquez and Las Bovedas while in the area.

A calm river with several boats docked along the shore, surrounded by lush greenery.

La Boquilla

1 out of top 10 points of interest in this area

The beaches and abundant dining options are top of the list for many visitors to La Boquilla. A stop by La Boquilla Beach or Las Americas International Convention Center might round out your trip.

Cartagena Centro Hotel Deals

Bastión Luxury Hotel

Bastión Luxury Hotel

Calle del Sargento No. 6-87 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$333 nightly
$333 total
Oct 31 - Nov 1
Bastión Luxury Hotel
Charleston Santa Teresa Cartagena

Charleston Santa Teresa Cartagena

Carrera 3 # 31-23 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$389 nightly
$389 total
Nov 1 - Nov 2
Charleston Santa Teresa Cartagena
Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Cra. 5 #36-16 ,Calle del Cuartel Cartagena
Fully refundableReserve now, pay when you stay
$331 nightly
$331 total
Nov 1 - Nov 2
9.4/10 Exceptional! (295 reviews)
"We had an amazing time and would staff again. The property is beautiful, the rooms are spacious and great location. It is close to everything but not in the busy part of town. The staff was very professional and accommodating. I requested to change rooms because I was given the one on the 1st floor ..."

Reviewed on Sep 29, 2026

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals
See all 4,080 properties in Cartagena Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Cartagena Centro attractions

A historic street with a prominent church, cobblestone path, and lush greenery.

San Pedro Claver Church and Convent

9.0/10 (623 reviews)
After visiting San Pedro Claver Church and Convent, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.
See properties
A coastal cityscape with a prominent cathedral and modern skyscrapers.

Cartagena Cathedral

9.2/10 (3,019 reviews)
After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.
See properties

Bolivar Square

9.2/10 (2,207 reviews)
Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.
See properties

Plaza Santo Domingo

9.2/10 (2,693 reviews)
Take a campus tour or just explore the area of Plaza Santo Domingo, during your travels in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.
See properties

University of Cartagena

8.6/10 (66 reviews)
Explore the campus of University of Cartagena, during your travels in Cartagena. Stroll along the beautiful beaches or seek out the local tours.
See properties

Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)
You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.
See properties

House of Gabriel Garcia Marquez

8.4/10 (70 reviews)
Find out about the history of Cartagena with a stop at House of Gabriel Garcia Marquez. Stroll along the beautiful beaches or seek out the local tours.
See properties

Casa del Marques de Premio Real

8.6/10 (17 reviews)
You can learn about the history of Cartagena with a visit to Casa del Marques de Premio Real. Amble around the area's beautiful beaches or seek out the local tours.
See properties

Things to do

Enjoy a beautiful sunset

Luxury Cartagena Sunset Pirate ship Adventure, Cannon Show&Drinks

$47
per adult
88% of travellers recommend
Luxury Cartagena Sunset Pirate ship Adventure, Cannon Show&Drinks
Black Lives Matter in the first free land in America, continuing the fight for equality.

Freedom Tour of Palenque

$110
per adult
86% of travellers recommend
Freedom Tour of Palenque
See all activities in Cartagena
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.