Cartagena Centro Vacations from $352

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Your Cartagena Centro Vacation

From its dining to its shopping and cafes, there are tons of incredible reasons to book a vacation package to Cartagena Centro. When you need to escape from it all, this seaside neighborhood has a spot just for you. Kick off your trip to Cartagena Centro by heading to nearby attractions such as San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Ayala Center. Whatever your dream Cartagena Centro vacation looks like, you can turn it into reality with Expedia.

The Latest Cartagena Centro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
1 Br Bright & Cozy loft in Cartagena

1 Br Bright & Cozy loft in Cartagena

3 out of 5
Bocagrande
Save 100% on your flight
per person
Sep 6 - Sep 13
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Cartagena (CTG)
10/10 Exceptional! (6 reviews)
This was an absolutely beautiful place. The pool and the apartment had everything we needed. I would definitely come back here.

Reviewed on Jul 23, 2024

Casa Colonial de Lujo Piscina & Rooftop

Casa Colonial de Lujo Piscina & Rooftop

3.5 out of 5
Cartagena Walled City
per person
Sep 7 - Sep 13
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Cartagena (CTG)
No reviews
Casa Kaimari by SoHo

Casa Kaimari by SoHo

2.5 out of 5
per person
Sep 14 - Sep 20
found 8 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Cartagena (CTG)
No reviews
Hotel Las Americas Torre del Mar

Hotel Las Americas Torre del Mar

4.5 out of 5
La Boquilla
Save 100% on your flight
per person
Sep 13 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)
8.8/10 Excellent! (1,006 reviews)
The breakfast was okay. The restaurant and restaurants and room service food was good. The beds were comfortable and the atmosphere was boom.

Reviewed on Jul 29, 2025

Charleston Santa Teresa Cartagena

Charleston Santa Teresa Cartagena

5 out of 5
Cartagena Walled City
Save 100% on your flight
per person
Sep 13 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cartagena (CTG)
9.4/10 Exceptional! (711 reviews)
You don’t need to go out from the Hotel. There is everything excellent and more.

Reviewed on Jul 27, 2025

Where to stay in Cartagena Centro

Find the best Cartagena Centro areas and neighborhoods for the activities you enjoy most. Learn more about Cartagena Centro
Ayala Center featuring modern architecture

Cartagena Walled City

3 out of top 10 points of interest in this area
4.5/5(1,184 area reviews)

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

Find hotels in Cartagena Walled City

Cartagena Centro Hotel Deals

Santa Catalina Hotel

Santa Catalina Hotel

4 out of 5
Carrera 6, Cl. del Candilejo #32 - 62, Cartagena
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $176 total per night from Jul 31 to Aug 1
$176 total
Jul 31 - Aug 1
9/10 Wonderful! (952 reviews)
"It is in the perfect location. Close to everything, all night life"

Reviewed on Jul 27, 2025

Santa Catalina Hotel
Bastión Luxury Hotel

Bastión Luxury Hotel

4.5 out of 5
Calle del Sargento No. 6-87, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
$297 nightly
The price is $297 total per night from Aug 17 to Aug 18
$297 total
Aug 17 - Aug 18
9.4/10 Exceptional! (1,005 reviews)
"I loved the convenience of being close to food spots, bars, and shopping. The location was safe during the day and night for walking."

Reviewed on Jul 23, 2025

Bastión Luxury Hotel
Charleston Santa Teresa Cartagena

Charleston Santa Teresa Cartagena

5 out of 5
Carrera 3 # 31-23, Centro Plaza de Santa Teresa, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
$282 nightly
The price is $282 total per night from Aug 3 to Aug 4
$282 total
Aug 3 - Aug 4
9.2/10 Wonderful! (721 reviews)
"You don’t need to go out from the Hotel. There is everything excellent and more."

Reviewed on Jul 27, 2025

Charleston Santa Teresa Cartagena
See all 3,633 properties in Cartagena Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Cartagena Centro

San Pedro Claver Church and Convent

San Pedro Claver Church and Convent

4.5/5(325 reviews)

Find out about the history of Cartagena when you take a trip to San Pedro Claver Church and Convent. Amble around the area's beautiful beaches or seek out the local tours.

San Pedro Claver Church and Convent
Chicken and waffles with green tomato syrup

Plaza Santo Domingo

4.5/5(419 reviews)

Take a campus tour or just explore the area of Plaza Santo Domingo, during your travels in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

Plaza Santo Domingo
So many squares and streets to explore in both the daylight and at night. Such a different place at both times of the day. The is one of many churches in the old city, located on Santos de Pierdra. #Details #TroveonTuesday

Catedral

5/5(1 review)

You can find out about the history of Cartagena with a stop at Catedral. Amble around the area's beautiful beaches or seek out the local tours.

Catedral

Things to do

The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat

The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat

$65
per adult
78% of travellers recommend
The ORIGINAL Rosario Islands Tour on Catamaran or Speedboat
Cartagena: 5 Must-See Rosario Islands Highlights with Lunch

Cartagena: 5 Must-See Rosario Islands Highlights with Lunch

$65
per adult
88% of travellers recommend
Cartagena: 5 Must-See Rosario Islands Highlights with Lunch
Cartagena: Sunset Open Bar Cruise in Catamaran or Speedboat

Cartagena: Sunset Open Bar Cruise in Catamaran or Speedboat

$20
per adult
Cartagena: Sunset Open Bar Cruise in Catamaran or Speedboat
See all activities in Cartagena
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.