
Cartagena Centro Vacations from $1,015
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Cartagena Centro Vacation
From its dining to its shopping and cafes, there are tons of incredible reasons to book a vacation package to Cartagena Centro. When you need to escape from it all, this seaside neighborhood has a spot just for you. Kick off your trip to Cartagena Centro by heading to nearby attractions such as San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Ayala Center. Whatever your dream Cartagena Centro vacation looks like, you can turn it into reality with Expedia.
The Latest Cartagena Centro Vacation Packages

Casa Bali Castillo View Private Pool & R
Reviewed on Feb 17, 2026



Hotel Boutique Casa del Coliseo
Reviewed on Aug 17, 2026
Where to stay in Cartagena Centro

Cartagena Walled City
Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

Bocagrande
Boasting the city's most prominent hotels, this upscale area offers shopping at Plaza Bocagrande and Nao Mall, and is close to the popular Ciudad Amurallada. Enjoy various dining options and easy access to the Transcaribe station.

Getsemani
Travelers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.

San Diego
San Diego is known for its ample dining options, and you can make a stop by House of Gabriel Garcia Marquez and Las Bovedas while in the area.

La Boquilla
The beaches and abundant dining options are top of the list for many visitors to La Boquilla. A stop by La Boquilla Beach or Las Americas International Convention Center might round out your trip.
Cartagena Centro Hotel Deals

Bastión Luxury Hotel

Charleston Santa Teresa Cartagena

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals
"We had an amazing time and would staff again. The property is beautiful, the rooms are spacious and great location. It is close to everything but not in the busy part of town. The staff was very professional and accommodating. I requested to change rooms because I was given the one on the 1st floor ..."
Reviewed on Sep 29, 2026
Stay near popular Cartagena Centro attractions

San Pedro Claver Church and Convent

Cartagena Cathedral
Bolivar Square
Plaza Santo Domingo
University of Cartagena
Palace of the Inquisition Cartagena Historical Museum
House of Gabriel Garcia Marquez
Casa del Marques de Premio Real
Things to do





















