Title: Central United States Vacation Packages 2026 from $381 | Expedia.com

[Central United States Travel Guide](https://expedia.com/Central-United-States.dx6209877)[Hotels in Central United States](https://expedia.com/Central-United-States-Hotels.d6209877.Travel-Guide-Hotels)[Vacation Rentals in Central United States](https://expedia.com/Central-United-States-Vacation-Rentals.d6209877.Travel-Guide-VacationRentals)[Flights to Central United States](https://expedia.com/Cheap-Flights-To-Central-United-States.d6209877.Travel-Guide-Flights)[Things to do in Central United States](https://expedia.com/Things-To-Do-In-Central-United-States.d6209877.Travel-Guide-Activities)[Car Rentals in Central United States](https://expedia.com/Car-Rentals-In-Central-United-States.d6209877.Car-Rental-Guide)

![](https://images.trvl-media.com/place/183262/3a16c968-2beb-4120-9eb8-792b4d2739dd.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Central United States Vacations from $381

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Photo by rikki cornett

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### Your Central United States Vacation

When it's time to set off on your next unforgettable adventure, a vacation package to Central United States is the answer. From this destination's friendly locals to all the other incredible things it's renowned for, there's a lot to discover. With so much to see and do on a trip to Central United States, it can be difficult to know where to begin. Kick off your travels in [New York](https://www.expedia.com/New-York.d178293.Destination-Travel-Guides) at Times Square and Central Park — two leading attractions here. Another great city worthy of a spot on your itinerary is [Orlando](https://www.expedia.com/Orlando.d178294.Destination-Travel-Guides). Don't miss Universal Studios Florida and Orlando International Premium Outlets. From the moment you book your Central United States vacation to when you return home, Expedia has your back every step of the way.

## The Latest Central United States vacation packages

Price found within the past 48 hours. Click for updated prices.

![Hampton Inn & Suites Houston Heights I-10](https://images.trvl-media.com/lodging/1000000/10000/500/490/e75c5d2e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hampton Inn & Suites Houston Heights I-10

Washington Ave./ Memorial Park

Save 100% on your flight

$381

per person

Apr 24 - Apr 27

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Houston (IAH)

9/10 Wonderful! (1,008 reviews)

Great stay. AC was loud. But over all Awesome

Reviewed on Mar 15, 2026

![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/109ddc6c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Greater Uptown

Save 100% on your flight

$545

per person

May 1 - May 5

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Houston (IAH)

8.2/10 Very Good! (3,441 reviews)

The hotel was pretty nice, great area with lots of places to walk to for shopping and dining. Could use some updating. The carpet, couch and tub looked well worn and almost dirty.

Reviewed on Mar 15, 2026

![Hotel Riu Plaza Chicago](https://images.trvl-media.com/lodging/103000000/102630000/102622800/102622712/3e21593f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Riu Plaza Chicago

Downtown Chicago

Save 100% on your flight

$503

per person

May 7 - May 10

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Chicago (ORD)

9.4/10 Exceptional! (3,495 reviews)

Staff was really nice and polite, Portuguese and Spanish speakers which was a must and breakfast buffet was amazing, highly recommended!

Reviewed on Mar 15, 2026

![JW Marriott Chicago](https://images.trvl-media.com/lodging/4000000/3540000/3538400/3538327/83e4c147_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### JW Marriott Chicago

Downtown Chicago

Save 100% on your flight

$448

per person

Apr 30 - May 2

found 1 hour ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Chicago (ORD)

9.2/10 Wonderful! (1,007 reviews)

The spa was wonderful, the room was clean and comfortable, and the staff was friendly. I only wish they had more food options. I have allergies and it was difficult to find items

Reviewed on Mar 9, 2026

![Fairmont Chicago at Millennium Park](https://images.trvl-media.com/lodging/1000000/20000/16000/15937/8bd99f5f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Fairmont Chicago at Millennium Park

Downtown Chicago

Save 100% on your flight

$620

per person

May 21 - May 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Chicago (ORD)

8.6/10 Excellent! (2,076 reviews)

Old hotel, no comforter in the bedroom, requested a change of the TV remote control.

Reviewed on Mar 15, 2026

Don't see what you're looking for?

See all available trips from Columbus to Central United States

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-15/2026-04-22/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=CHI&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6209877)

## Where to stay in Central United States

Find the best Central United States areas and neighborhoods for the activities you enjoy most. [Learn more about Central United States](https://expedia.com/Central-United-States.dx6209877)

![Downtown Chicago showing a city](https://images.trvl-media.com/place/6350699/f8ae2db6-94cc-4898-aa46-e275588c3787.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown Chicago

1 out of top 10 points of interest in this area

 The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art. 

[Find hotel + flight trips in Downtown Chicago](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20Chicago&DestID=6350699&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Downtown Nashville which includes a city, a sunset and boating](https://images.trvl-media.com/place/6059741/6a1d3a8f-1974-4484-bfc0-bef896cfaee5.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown Nashville

4/5(5,801 area reviews)

 Sounds of country and honky-tonk resonate around the streets of Music City. Watch a show, attend a hockey match and walk in the footsteps of U.S. presidents. 

[Find hotel + flight trips in Downtown Nashville](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20Nashville&DestID=6059741&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Vibrant atmosphere in the French Quarter showcasing culture and community on a sunny day](https://images.trvl-media.com/place/800072/d97dfdd9-81f2-4601-a10e-054fee1acd4f.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### French Quarter

4.5/5(9,221 area reviews)

 Historic buildings and lively atmosphere entice tourists and locals alike, offering live music, street performances, and vibrant nightlife. Must-see spots include Jackson Square, St. Louis Cathedral, and Café du Monde. 

[Find hotel + flight trips in French Quarter](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=French%20Quarter&DestID=800072&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Illuminated paths and modern buildings create a vibrant atmosphere at Discovery Green in Houston, Texas during the evening](https://images.trvl-media.com/place/6082195/fa70078e-ab30-43a5-aa06-e3a763da2444.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown Houston

4.5/5(2,300 area reviews)

 Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines. 

[Find hotel + flight trips in Downtown Houston](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20Houston&DestID=800037&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Downtown Austin showing street scenes and an administrative buidling](https://images.trvl-media.com/place/6059085/ea876a79-05ba-46c9-8155-49e50c60cc4e.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Downtown Austin

4/5(3,367 area reviews)

 Central business district with high-rise buildings, Downtown Austin offers shopping at Second Street District and Sixth Street, art at Contemporary Austin Jones Center, and sights like Texas State Capitol. Accessible via Capital MetroRail. 

[Find hotel + flight trips in Downtown Austin](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20Austin&DestID=6059085&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

### Discover the most popular places to visit in Central United States

![River Walk featuring night scenes and a river or creek](https://images.trvl-media.com/place/6125866/3223be4e-1629-469b-8357-69494f446850.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### River Walk

4.5/5(7,278 reviews)

When you visit San Antonio, this neighborhood will keep you entertained for days, from morning coffee to an evening theater performance.

[](https://expedia.com/River-Walk-Downtown-San-Antonio.d6125866.Vacation-Attraction)

![Wrigley Field featuring cbd, a sporting event and a city](https://images.trvl-media.com/place/6034754/d10ea4fa-9a61-425f-b749-3325e9303223.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Wrigley Field

4.5/5(2,128 reviews)

Tour the iconic grounds and catch a game March through September at Chicago’s beloved baseball stadium.

[](https://expedia.com/Wrigley-Field-Lakeview.d6034754.Vacation-Attraction)

![Dollywood which includes signage and rides](https://images.trvl-media.com/place/6091011/437b6e0e-1d47-479e-983c-b63e35103a5b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Dollywood

4.5/5(1,639 reviews)

This amusement park owned by country singer Dolly Parton lures fans with its roller coasters and children’s rides, museums and live music and theater shows.

[](https://expedia.com/Dollywood-Tennessee.d6091011.Vacation-Attraction)

## Central United States Hotel Deals

![Congress Plaza Hotel](https://images.trvl-media.com/lodging/1000000/10000/6500/6452/11b63ec2_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Congress Plaza Hotel

520 South Michigan Avenue Chicago IL

Fully refundableReserve now, pay when you stay

$103 nightly

$121 total

Apr 1 - Apr 2

Total with taxes and fees

8/10 Very Good! (9,936 reviews)

Room was unclean, reeked of cigarettes and other smells.

Reviewed on Mar 15, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=6452&PinnedHotelID=6452&HadPinnedHotel=true&regionId=6209877)

![Embassy Suites by Hilton Chicago Downtown River North](https://images.trvl-media.com/lodging/1000000/20000/11600/11580/24d28405_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Embassy Suites by Hilton Chicago Downtown River North

600 N State St Chicago IL

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Mar 22 - Mar 23

Total with taxes and fees

8.6/10 Excellent! (5,744 reviews)

Yes great

Reviewed on Mar 15, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=11580&PinnedHotelID=11580&HadPinnedHotel=true&regionId=6209877)

![Hotel Riu Plaza Chicago](https://images.trvl-media.com/lodging/103000000/102630000/102622800/102622712/3e21593f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Riu Plaza Chicago

150 East Ontario Street Chicago IL

Fully refundableReserve now, pay when you stay

$156 nightly

$183 total

Mar 22 - Mar 23

Total with taxes and fees

9.4/10 Exceptional! (3,536 reviews)

Staff was really nice and polite, Portuguese and Spanish speakers which was a must and breakfast buffet was amazing, highly recommended!

Reviewed on Mar 15, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=102622712&PinnedHotelID=102622712&HadPinnedHotel=true&regionId=6209877)

[See all 305,453 properties in Central United States](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F16%2F2026&endDate=3%2F17%2F2026&regionId=6209877)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Central United States Vacation Packages

## Central United States Essential Information

| Language        | English                    |
| --------------- | -------------------------- |
| Currency        | U.S dollars                |
| Closest Airport | O'Hare Intl. Airport (ORD) |

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