Commerce, MO

Travel Guide

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Dec 1 to Dec 2
$102 total
Dec 1 - Dec 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
Clean rooms. Very comfortable bed. Friendly staff

Reviewed on Nov 17, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
$96 nightly
The price is $109 total per night from Nov 24 to Nov 25
$109 total
Nov 24 - Nov 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (456 reviews)
Great room, close to downtown, awesome food options in the venue as well. Really nice views of the river.

Reviewed on Nov 19, 2025

The Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Nov 27 to Nov 28
$79 total
Nov 27 - Nov 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
Everything was great.

Reviewed on Nov 21, 2025

Pear Tree Inn Cape Girardeau West
See all 79 properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse

Cape Girardeau MO
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (26 reviews)
This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!

Reviewed on Nov 2, 2025

The Twisted Sassafras Treehouse
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a garden, and in-room jetted tubs. Popular attractions eDen Spa & Salon and Riverfront Park are located ...
9.4/10 Exceptional! (43 reviews)
Great location for downtown cape! Sister weekend for us went well. Only issues: roaches in kitchen and front door was difficult to close/secure.

Reviewed on Oct 30, 2025

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Cape Girardeau MO
Book a stay at this family-friendly vacation home in Cape Girardeau. Enjoy free WiFi, a water park, and a garden. Popular attractions Isle Casino Cape Girardeau ...
10/10 Exceptional! (26 reviews)
This home is picture perfect!! Chip (and Busy) were wonderful hosts and gave a grand tour of the home along with pointing out architectural and period details in this historic Dutch Colonial Revival. The property is set up away from the street in a very quiet neighborhood. Everything we could have ...

Reviewed on Nov 14, 2025

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
See all properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.