Commerce, MO

Travel Guide

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
$100 nightly
The price is $113 total per night from Sep 3 to Sep 4
$113 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,006 reviews)
"The stay was great"

Reviewed on Aug 29, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
$104 nightly
The price is $117 total per night from Sep 28 to Sep 29
$117 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
9.4/10 Exceptional! (647 reviews)
"Nice view of the river. The staff was nice."

Reviewed on Aug 23, 2026

The Riverview
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Sep 14 to Sep 15
$108 total
Sep 14 - Sep 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,002 reviews)
"This was a great stay offering a happy hour (actually an hour and a half) with free heavy appetizers and three free alcohol drinks. Also a good free breakfast. Nice pool area."

Reviewed on Aug 28, 2026

Drury Inn & Suites Sikeston, MO
See all 86 properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
Stay at this cabin in Alexander County. Enjoy an in-room coffeemaker and air conditioning.
Peaceful secluded cabin located near Horseshoe Lake
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Show Me Center and Century ...
9.8/10 Exceptional! (29 reviews)
"Is a very welcoming home. Stayed there with my family and my kids loved the house. Is very big and spacious. A lot of amenities was provided like kitchen supplies, extra blankets and towels. The only thing I will change would be the entrance glass door even dough my dog loved it my kids were a little ..."

Reviewed on Aug 20, 2026

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions eDen Spa & Salon and The Glenn House are ...
Serenity South -- Gardens, River-Views, and Refreshing Space
See all properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.