Commerce, MO

Travel Guide

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Jan 12 to Jan 13
$102 total
Jan 12 - Jan 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,011 reviews)
Breakfast buffet was very good. We ate at the restaurant onsite, and the food was very good. The room always spacious and nice. We were on the road side and you could hear a lot of noise from the trucks, loud cars, etc on the road.

Reviewed on Jan 4, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
$96 nightly
The price is $109 total per night from Jan 12 to Jan 13
$109 total
Jan 12 - Jan 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (484 reviews)
Excellent stay. Will come again

Reviewed on Dec 30, 2025

The Riverview
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
$84 nightly
The price is $91 total per night from Jan 11 to Jan 12
$91 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (682 reviews)
Warm lights in rooms and hall ways would be great, currently white (day) lights everywhere

Reviewed on Jan 4, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
See all 80 properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Rested Duck Mallard Room

The Rested Duck Mallard Room

Olive Branch IL
Stay at this cabin in Alexander County. Enjoy air conditioning.
9.2/10 Wonderful! (25 reviews)
It was fine. It was fairly clean and the bed was comfortable. No where to put anything down in the bathroom.

Reviewed on Oct 19, 2025

The Rested Duck Mallard Room
Little Blue Cottage on Spanish

Little Blue Cottage on Spanish

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Popular attractions eDen Spa & Salon and The Glenn House are located nearby.
8.4/10 Very Good! (48 reviews)
The amenities were in pretty strange conditions. Not non functional. Just strange. Fairly priced. I would stay again

Reviewed on Oct 30, 2025

Little Blue Cottage on Spanish
The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse

Cape Girardeau MO
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (28 reviews)
It was very nice and well let. Quaint and quiet weekend. Just what we needed.

Reviewed on Dec 24, 2025

The Twisted Sassafras Treehouse
See all properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.