De Soto Vacations from $391

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your De Soto Vacation

Get ready to experience De Soto in your own style with a custom De Soto vacation package! Uncovering the best parts of this interesting city is easy with a base in a neighborhood such as Lake Quivira, which is great for golfing, among many other things. Hoping to see some sights? Spend your days enjoying popular attractions such as Medicines Hall of Fame and Museum during your trip to De Soto. Check out Expedia's extensive range of travel options and book your ultimate vacation to De Soto now.

The Latest De Soto vacation packages

Price found within the past 48 hours. Click for updated prices.
Ameristar Casino Hotel Kansas City

Ameristar Casino Hotel Kansas City

4 out of 5
Birmingham Bottoms
Price was $524, price is now $391 per person
$391
per person
Sep 26 - Sep 28
found 16 hours ago
Roundtrip flight included
Charlotte (CLT) to Kansas City (MCI)
8.6/10 Excellent! (1,129 reviews)
Excellent accommodation for a quick trip to KC

Reviewed on Jul 13, 2026

Leavenworth Local Hotel

Leavenworth Local Hotel

2.5 out of 5
Price was $572, price is now $441 per person
$441
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Charlotte (CLT) to Kansas City (MCI)
8.8/10 Excellent! (404 reviews)
I liked how friendly and helpful the workers were

Reviewed on Jul 12, 2026

Margaritaville Hotel Kansas City

Margaritaville Hotel Kansas City

4 out of 5
I-435 West
Price was $878, price is now $703 per person
$703
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Charlotte (CLT) to Kansas City (MCI)
9.4/10 Exceptional! (692 reviews)
Easy to book. It was nice to have a small resort feel. Food is great.

Reviewed on Jul 12, 2026

AC Hotel Lenexa City Center

AC Hotel Lenexa City Center

3 out of 5
Lenexa City Center
Price was $607, price is now $491 per person
$491
per person
Sep 26 - Sep 28
found 16 hours ago
Roundtrip flight included
Charlotte (CLT) to Kansas City (MCI)
No reviews

The Inn at Meadowbrook

The Inn at Meadowbrook

4 out of 5
Price was $618, price is now $503 per person
$503
per person
Sep 13 - Sep 15
found 9 hours ago
Roundtrip flight included
Denver (DEN) to Kansas City (MCI)
9.8/10 Exceptional! (448 reviews)
Everything was just amazing!!

Reviewed on Jun 5, 2026

Don't see what you're looking for?
See all available trips from Columbus to De Soto
View all trips

De Soto Hotel Deals

Margaritaville Hotel Kansas City

Margaritaville Hotel Kansas City

4 out of 5
1491 North 98th Terrace Kansas City KS
$202 nightly
The price is $245 total per night from Aug 9 to Aug 10
$245 total
Aug 9 - Aug 10
Total with taxes and fees
9.2/10 Wonderful! (732 reviews)
"Easy to book. It was nice to have a small resort feel. Food is great."

Reviewed on Jul 12, 2026

Margaritaville Hotel Kansas City
The Fontaine

The Fontaine

4.5 out of 5
901 W. 48th Place Kansas City MO
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $189 total per night from Aug 11 to Aug 12
$189 total
Aug 11 - Aug 12
Total with taxes and fees
9/10 Wonderful! (1,026 reviews)
"Than you"

Reviewed on Jul 13, 2026

The Fontaine
Hyatt Place Kansas City/Overland Park/Convention Center

Hyatt Place Kansas City/Overland Park/Convention Center

3 out of 5
5001 W 110th St Overland Park KS
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $124 total per night from Jul 26 to Jul 27
$124 total
Jul 26 - Jul 27
Total with taxes and fees
9/10 Wonderful! (1,009 reviews)
"Nice people, clean, quiet, comfortable. Will stay again"

Reviewed on Jul 12, 2026

Hyatt Place Kansas City/Overland Park/Convention Center
See all 1,575 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best De Soto Vacation Packages

De Soto Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Kansas City Intl. Airport (MCI)
Population
6,100
Max Temp Winter
40ºF
Max Temp Summer
85ºF
Top Sights
Johnson County Museum, Mid-America Sports Complex and Tomahawk Hills Golf Course

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a De Soto vacation package cost?
You can pick up a vacation package to this destination from $391 on Expedia. But how much your vacation to De Soto costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to De Soto?
You can typically find lower rates and greater availability in November, December and January. Explore our cheap De Soto vacation packages and you could land some great off-season deals.
How many days is enough for De Soto?
The ideal duration for your De Soto vacation depends on what you'd like to do and see. Typically, a few days to a week will give you time to check out all the leading sights and discover some hidden gems along the way.
How to find the best De Soto package deals?
Use Expedia's filters to help you find some of the best De Soto package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or browse for De Soto package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a De Soto vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the freedom to create a customized De Soto vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to De Soto?
If you're planning a spur-of-the-moment De Soto getaway, check out our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can find sensational deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later De Soto vacation packages?
Set off on your dream getaway to De Soto with Expedia's Book Now, Pay Later vacations. There's no need to save up or hold off until your next paycheck — we've teamed up with online lender Affirm to offer you financial flexibility. Our vacation packages with payment plans let you split the cost over 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to stay on budget and snap up bargains before they disappear.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.