Vacation Rentals in Cape Girardeau County
- Bundle & SaveGet more, spend less whenever you see Bundle & Save deals
- OneKeyCashEarn OneKeyCash on all your eligible bookings
- Upfront pricingWe are not like the others - we include taxes and fees
Top Cities in Cape Girardeau County

Cape Girardeau
Top Vacation Rentals in Cape Girardeau County

The Twisted Sassafras Treehouse

Little Blue Cottage on Spanish

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Serenity South -- Gardens, River-Views, and Refreshing Space

On the Shawnee Wine Trail

Exquisite views of Shawnee National Forest seen from a private, covered hot tub.
Top Cape Girardeau County Hotel Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Find out more about Cape Girardeau County
Discover your perfect Cape Girardeau County vacation rental with Expedia
How many vacation rentals are available in Cape Girardeau County?
Expedia has plenty of vacation rentals to choose from in and around Cape Girardeau County, so you’re guaranteed to find the right one for you.
How much is a vacation rental in Cape Girardeau County?
The selection of Cape Girardeau County vacation rentals we have selected for you start as low as $101 per night. Entering your travel dates in the search wizard you might find even better deals!
What type of vacation rental can I get in Cape Girardeau County?
Vacation rentals in Cape Girardeau County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Cape Girardeau County vacation rentals to suit everyone.
Why should I choose a vacation rental in Cape Girardeau County?
Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Cape Girardeau County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.
How do I find the best deal on a vacation rental in Cape Girardeau County?
Find vacation rentals in Cape Girardeau County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Cape Girardeau County.
What amenities are available in a vacation rental in Cape Girardeau County?
The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Cape Girardeau County vacation rentals designed to suit every budget and trip type.
When is the best time to stay in a vacation rental in Cape Girardeau County?
Everytime is a great time to head to Cape Girardeau County! Staying in a Cape Girardeau County vacation rentals you will always find lots going on to keep you entertained.
Why book a vacation rental with Expedia?
Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Cape Girardeau County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Cape Girardeau County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Cape Girardeau County, you can save even more.
Can I cancel my vacation rental through Expedia?
Yes, you can cancel or change your Cape Girardeau County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.
Explore a world of travel with Expedia
- Vacation Homes in Cape Girardeau County
- Cabin Rentals in Cape Girardeau County
- Apartments in Cape Girardeau County
- Cottages in Cape Girardeau County
- Farmstay in Cape Girardeau County
- RV Parks in Cape Girardeau County
- Lodges in Cape Girardeau County
- B&B in Cape Girardeau County
- Motels in Cape Girardeau County
- Aparthotels in Cape Girardeau County
















































































