Panama Luxury Hotels from $148 - Fully Refundable Options

Top Cities in Panama

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Pick from 67 Panama Luxury Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Relax in a tranquil setting surrounded by a clear pool and palm trees.

"Always an exceptional stay. "

$212 nightly

Aug 16 - Aug 17

Total includes taxes and fees

Enjoy a panoramic view of the city skyline from this stylish living room.

"This was a amazing property extremely clean very hospitable"

$218 nightly

Sep 2 - Sep 3

Total includes taxes and fees

Relax in style with a city view from this outdoor seating area, featuring round tables and comfortable wicker chairs with cushions.

"Lovely stay "

$215 nightly

Aug 16 - Aug 17

Total includes taxes and fees

Stunning hotel with a classic, symmetrical facade and beautifully maintained grounds.

"Beautiful property and friendly staff!"

$209 nightly

Aug 13 - Aug 14

Total includes taxes and fees

Enjoy a panoramic view of the city skyline from this modern office space with floor-to-ceiling windows.

"2nd stay at Sortis Hotel in Panama. Never disappoints. Breakfast Buffett incredible and staff pleasant and attentive! Will stay there again!"

$159 nightly

Aug 4 - Aug 5

Total includes taxes and fees

Relax by the pool surrounded by lounge chairs and umbrellas, with a view of the city skyline.

"The hotel was well maintained. The surrounding area has lots to offer in terms of food, entertainment and outdoor activities "

$212 nightly

Aug 23 - Aug 24

Total includes taxes and fees

"This is THE place to stay in Panama City... it's location, friendly accommodating staff, and the amenities are fantastic. The rooms were wonderful, clean and bright. We tried Tauro (steakhouse) and the Bazaar - they were both delicious and the service excellent. We literally partied like rock stars at their rooftop restaurant, and at the wonderful outdoor infinity pool as well. We will definitely be returning! "