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Vacation Rentals in Scott County

Top Cities in Scott County

Our top choices for Scott County vacation rentals

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (29 reviews)
"This was an amazing property. We our stay here with our doodles while hiking and exploring Shawnee Forest. Private, comfortable and unique! "
United States
Tammy &.
$174 nightly
The price is $184
Jul 1 - Jul 2
Total with taxes and fees
Peaceful secluded cabin located near Horseshoe Lake

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (105 reviews)
"Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location "
United States
carlton h.
$265 nightly
The price is $281
Jul 1 - Jul 2
Total with taxes and fees
Charming cottage overlooking Lake Acre

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
$101 nightly
The price is $108
Jul 2 - Jul 3
Total with taxes and fees
Little Blue Cottage on Spanish

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (42 reviews)
"Peaceful and suited our needs perfectly."
United States
Matthew
$133 nightly
The price is $140
Jul 1 - Jul 2
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake

Vibrant Lofted Tiny Home

Vibrant Lofted Tiny Home
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"The tiny house was adorable, clean, and everything we expected. We can’t wait to stay in the others. We definitely recommend staying here. Lisa and Holly have done a wonderful job. Holly was great at getting back to me. Loved everything about our stay and the trip. Thank you so much"
United States
Kim K.
$223 nightly
The price is $234
Jul 1 - Jul 2
Total with taxes and fees
Vibrant Lofted Tiny Home

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (9 reviews)
"It was a beautiful building and just what my sister in law needed to stay at after a local event. "
United States
Heather C.
$244 nightly
The price is $259
Jul 1 - Jul 2
Total with taxes and fees
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"It’s very nice and comfortable "
United States
John S.
$133 nightly
The price is $140
Jul 1 - Jul 2
Total with taxes and fees
The Rested Duck Mallard Room

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (22 reviews)
"Nice little Cabin in a beautiful area. Blair and her family were wonderful!"
United States
Keegan C.
$292 nightly
The price is $307
Jul 5 - Jul 6
Total with taxes and fees
Charming Secluded Getaway Cabin within minutes of amenities

A-Frame Cottage with Deck in Charming Inspiration Village

A-Frame Cottage with Deck in Charming Inspiration Village
Cape Girardeau
$231 nightly
The price is $242
Jul 1 - Jul 2
Total with taxes and fees
A-Frame Cottage with Deck in Charming Inspiration Village

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (34 reviews)
"Nice, quiet, close to shopping & restaurants"
United States
Jaime M.
$300 nightly
The price is $315
Jul 7 - Jul 8
Total with taxes and fees
The Twisted Sassafras Treehouse

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
$198 nightly
The price is $198
Jul 5 - Jul 6
Total with taxes and fees
The Cottage, Rusted Route Farms

Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck

Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck
Cape Girardeau
$218 nightly
The price is $229
Jul 5 - Jul 6
Total with taxes and fees
Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (33 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
$199 nightly
The price is $214
Jul 1 - Jul 2
Total with taxes and fees
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (36 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
$172 nightly
The price is $181
Jul 6 - Jul 7
Total with taxes and fees
Relax in the country at Countryside Villas! - Villa A

Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
10.0 out of 10, Exceptional, (12 reviews)
"It was great. "
United States
Benjamin Q.
$170 nightly
The price is $179
Jul 22 - Jul 23
Total with taxes and fees
Villa B offers peace and quiet with beautiful views of the countryside.

European Inspired Lofted Cottage in Tiny Home Village

European Inspired Lofted Cottage in Tiny Home Village
Cape Girardeau
$216 nightly
The price is $227
Jul 1 - Jul 2
Total with taxes and fees
European Inspired Lofted Cottage in Tiny Home Village

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
10.0 out of 10, Exceptional, (1 review)
"Nice quiet peaceful property with a large pond in the woods"
United States
Brad M.
$225 nightly
The price is $238
Jul 1 - Jul 2
Total with taxes and fees
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (159 reviews)
"Nice location to river front and downtown. Very lovely place."
United States
Marcie R.
$228 nightly
The price is $247
Jul 24 - Jul 25
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
$160 nightly
The price is $167
Jul 5 - Jul 6
Total with taxes and fees
Studio Apt | King Bed, Full Kitchen · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays
Cape Girardeau
Modern Boho Getaway · 1BR Apartment · By KeenStays
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Scott County Hotel Reviews

Find out more about Scott County

Discover your perfect Scott County vacation rental with Expedia

How many vacation rentals are available in Scott County?


Expedia has plenty of vacation rentals to choose from in and around  Scott County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Scott County?


The selection of Scott County vacation rentals we have selected for you start as low as $108 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Scott County?


Vacation rentals in Scott County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Scott County vacation rentals to suit everyone. 


Why should I choose a vacation rental in Scott County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Scott County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Scott County?


Find vacation rentals in Scott County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Scott County.  


What amenities are available in a vacation rental in Scott County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Scott County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Scott County?   


Everytime is a great time to head to Scott County! Staying in a Scott County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Scott County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Scott County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Scott County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Scott County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.