Downtown Syracuse Vacations from $319

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Your Downtown Syracuse Vacation

A sought-after riverside neighborhood, Downtown Syracuse tempts travelers with its bars and pubs, nightlife and shopping. Lock in a vacation package to Downtown Syracuse and experience all the highlights for yourself. Some nearby attractions to visit during your trip to Downtown Syracuse include Museum of Science and Technology, Erie Canal Museum and Syracuse University. Stop dreaming and start doing. When you're ready to lock in your next vacation to Downtown Syracuse, Expedia will help you get there.

The Latest Downtown Syracuse Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Randolph House Hotel, Trademark Collection by Wyndham

Randolph House Hotel, Trademark Collection by Wyndham

3 out of 5
Price was $427, price is now $319 per person
$319
per person
Nov 10 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Syracuse (SYR)
7/10 Good! (879 reviews)
This was a very reasonably priced option in the Syracuse University area. The staff was very friendly and responsive. It looks like they are renovating and starting to update rooms to improve the experience.

Reviewed on Aug 25, 2025

The Craftsman Inn & Suites

The Craftsman Inn & Suites

3.5 out of 5
Price was $608, price is now $437 per person
$437
per person
Nov 10 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Syracuse (SYR)
9.4/10 Exceptional! (1,183 reviews)
The decor is nice, beds are comfortable. The room is mostly clean. however what holds me back to give 10 out of 10 is the shower stall has a bit of mold at the bottom and they could use a better more function and adjustable shower head. Overall I highly recommend this Hotel and will come back again.

Reviewed on Aug 25, 2025

Comfort Inn & Suites Liverpool - Syracuse

Comfort Inn & Suites Liverpool - Syracuse

2.5 out of 5
Price was $504, price is now $388 per person
$388
per person
Nov 10 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Syracuse (SYR)
8.8/10 Excellent! (446 reviews)
Looked and smelled clean upon entry, efficient check in, plenty of parking. Super close to stores and restaurants. Pool times were a plus.

Reviewed on Aug 26, 2025

Cicero Grand - Syracuse North

Cicero Grand - Syracuse North

2.5 out of 5
Price was $449, price is now $349 per person
$349
per person
Nov 10 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Syracuse (SYR)
7.6/10 Good! (1,000 reviews)
The sofa in the room was stained, old and dirty. The tv is very small AND all of the channels kept going in and out (I'm assuming they have a dish). Front desk Woman was very pleasant.

Reviewed on Aug 26, 2025

Cresthill Suites Syracuse

Cresthill Suites Syracuse

3 out of 5
Price was $493, price is now $392 per person
$392
per person
Nov 10 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Syracuse (SYR)
7.8/10 Good! (1,122 reviews)
Pro: Showers were high pressure and volume, beds comfortable, Cons: smelled like pets, sheets didnt fit bed, shabby workmanship (caulking, painting, etc.), kitchen not equiped for use.

Reviewed on Aug 22, 2025

Where to stay in Downtown Syracuse

Find the best Downtown Syracuse areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Syracuse
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Lakefront

1 out of top 10 points of interest in this area
4/5(60 area reviews)

Bordering Downtown Syracuse, Lakefront features the charming areas of Franklin Square and Inner Harbor. Explore the historic O.M. Edwards Building, listed on the National Register of Historic Places.

Find hotels in Lakefront

Downtown Syracuse Hotel Deals

Marriott Syracuse Downtown

Marriott Syracuse Downtown

4 out of 5
100 East Onondaga Street, Syracuse, NY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Aug 31 to Sep 1
$148 total
Aug 31 - Sep 1
Total with taxes and fees
8.4/10 Very Good! (1,005 reviews)
"We moved our daughter into Syracuse University and stayed at this hotel. The staff and accommodations were great! We never had to wait for anything we needed. It’s a beautiful hotel and will be our first choice place to stay near the university!"

Reviewed on Aug 25, 2025

Marriott Syracuse Downtown
Best Western Syracuse Downtown Hotel and Suites

Best Western Syracuse Downtown Hotel and Suites

3 out of 5
416 S Clinton St, Syracuse, NY
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Aug 31 to Sep 1
$164 total
Aug 31 - Sep 1
Total with taxes and fees
8.2/10 Very Good! (531 reviews)
"Great location and room was large and comfortable."

Reviewed on Aug 25, 2025

Best Western Syracuse Downtown Hotel and Suites
Courtyard Syracuse Downtown At Armory Square

Courtyard Syracuse Downtown At Armory Square

3 out of 5
300 West Fayette Street, Syracuse, NY
$144 nightly
The price is $168 total per night from Sep 14 to Sep 15
$168 total
Sep 14 - Sep 15
Total with taxes and fees
8.4/10 Very Good! (624 reviews)
"Customer horrible"

Reviewed on Aug 23, 2025

Courtyard Syracuse Downtown At Armory Square
See all 557 properties in Downtown Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Downtown Syracuse

Armory Square featuring a city

Armory Square

Home to Syracuse’s highest concentration of bars and restaurants, this lively city square is the perfect place for a night out in Central New York.

Armory Square
Landmark Theatre showing interior views and heritage elements

Landmark Theatre

See Broadway musicals, comedy or rock shows at this beautiful and supposedly haunted 1920s venue just off Syracuse’s Armory Square.

Landmark Theatre
Clinton Square which includes heritage architecture, a garden and a city

Clinton Square

Nestled in the heart of Syracuse’s downtown, this historic plaza is known for its civic mindedness, hosting countless festivals and a community ice skating rink.

Clinton Square

Things to do

1 Hour Walk-In Axe Throwing Experience Syracuse

30-minute Walk-In Axe Throwing Experience Syracuse

$22
per adult
100% of travellers recommend
30-minute Walk-In Axe Throwing Experience Syracuse
See all activities in Syracuse
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.