Downtown Syracuse Vacations from $360
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Your Downtown Syracuse Vacation
A sought-after riverside neighborhood, Downtown Syracuse tempts travelers with its bars and pubs, nightlife and shopping. Lock in a vacation package to Downtown Syracuse and experience all the highlights for yourself. Some nearby attractions to visit during your trip to Downtown Syracuse include Museum of Science and Technology, Erie Canal Museum and Syracuse University. Stop dreaming and start doing. When you're ready to lock in your next vacation to Downtown Syracuse, Expedia will help you get there.
The Latest Downtown Syracuse Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Randolph Hotel Liverpool/Syracuse/Airport West, Trademark
Price was $439, price is now $360 per person
$360
per person
Oct 1 - Oct 6
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Syracuse (SYR)
6.4/10 (1,012 reviews)
I've stayed here before and always had connecting rooms. This time I did not get connecting rooms even though I had asked for them. On the day of check-in, 2hrs before arrival I was assured of connecting rooms. At check-in, they told me they did not have connecting rooms. It was to late to cancel and find another hotel.
Reviewed on Jul 16, 2026
Marriott Syracuse Downtown
Downtown Syracuse
Save 100% on your flight
Price was $1,210, price is now $940 per person
$940
per person
Oct 1 - Oct 6
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Syracuse (SYR)
8.6/10 Excellent! (1,002 reviews)
The room was very nice and the wait staff at breakfast was exceptional!
Reviewed on Jul 11, 2026
Comfort Inn - NYS Fairgrounds
Price was $603, price is now $506 per person
$506
per person
Oct 1 - Oct 6
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Syracuse (SYR)
7.8/10 Good! (786 reviews)
This comfort inn is terrible. Dirty, old, broken. My door would not close because someone kicked it out before and broke a lock.
Reviewed on Jul 16, 2026
Embassy Suites by Hilton Syracuse Destiny USA
Lakefront
Price was $1,042, price is now $879 per person
$879
per person
Oct 1 - Oct 6
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Syracuse (SYR)
8.4/10 Very Good! (1,106 reviews)
Had a shower that you just step in but the rab bar was not attached to the wall by the toilet..felt totally unsafe
Reviewed on Jul 16, 2026
Where to stay in Downtown Syracuse
Find the best Downtown Syracuse areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Syracuse
Eastside
2 out of top 10 points of interest in this area
Bordering Downtown Syracuse and University Hill, Near Eastside boasts historic gems like the Gustav Stickley House and Collins House. Explore the rich history while staying close to downtown attractions.
Downtown Syracuse Hotel Deals
Marriott Syracuse Downtown
100 East Onondaga Street Syracuse NY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Aug 2 to Aug 3
$158 total
Aug 2 - Aug 3
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
"The room was very nice and the wait staff at breakfast was exceptional!"
Reviewed on Jul 11, 2026
Courtyard Syracuse Downtown At Armory Square
300 West Fayette Street Syracuse NY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Aug 2 to Aug 3
$158 total
Aug 2 - Aug 3
Total with taxes and fees
8.6/10 Excellent! (735 reviews)
"Everything was great from the check-in with Nikkita to the convenient location to food. The room was clean and bedding was comfortable. We enjoyed our stay."
Reviewed on Jul 16, 2026
Best Western Syracuse Downtown Hotel and Suites
416 S Clinton St Syracuse NY
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $145 total per night from Jul 19 to Jul 20
$145 total
Jul 19 - Jul 20
Total with taxes and fees
8.4/10 Very Good! (701 reviews)
"Great location and good price."
Reviewed on Jul 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Downtown Syracuse attractions
Things to do
1-Hour Walk-In Axe Throwing Experience Syracuse
$37
per adult
100% of travellers recommend
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- Le Moyne College
- Onondaga County War Memorial
- Destiny USA
- Suny Upstate Medical University
- Nbt Bank Stadium
- Visit Downtown Syracuse
- Where to stay in Syracuse
- New York Vacations
- Solvay Vacations
- Erie Canal Museum
- Lake Onondaga
- Everson Museum of Art
- Dewitt Vacations
- Clinton Square
- Syracuse VA Medical Center
- East Syracuse Vacations
- Syracuse University
- St. Joseph's Hospital Health Center
- Sainte Marie among the Iroquois
- Green Lakes State Park
- Visit Syracuse
- Onondaga Lake Visitors Center
- Onondaga Lake Park
- Visit New York
- Armory Square
- Museum of International Masks and Puppets
- Rosamond Gifford Zoo
- E.m. Mills Rose Garden
- Wonderworks
- Salt Museum
- Landmark Theatre
- Museum of Science and Technology
- Crouse Hospital
- New York State Fairgrounds
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.