Downtown Syracuse Vacations from $308

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Your Downtown Syracuse Vacation

A sought-after riverside neighborhood, Downtown Syracuse tempts travelers with its bars and pubs, nightlife and shopping. Lock in a vacation package to Downtown Syracuse and experience all the highlights for yourself. Some nearby attractions to visit during your trip to Downtown Syracuse include Museum of Science and Technology, Erie Canal Museum and Syracuse University. Stop dreaming and start doing. When you're ready to lock in your next vacation to Downtown Syracuse, Expedia will help you get there.

The Latest Downtown Syracuse Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Comfort Inn & Suites Liverpool - Syracuse

Comfort Inn & Suites Liverpool - Syracuse

2.5 out of 5
Price was $370, price is now $308 per person
$308
per person
Jun 21 - Jun 23
found 8 hours ago
Roundtrip flight included
New York (NYC) to Syracuse (SYR)
8.8/10 Excellent! (686 reviews)
Great hotel everything was as expected clean room good breakfast close to many shops and restaurants only thing I wish the pool was heated was a little cold the kids still swam and had a blast

Reviewed on Apr 13, 2026

DoubleTree by Hilton Hotel Syracuse

DoubleTree by Hilton Hotel Syracuse

4 out of 5
Price was $1,196, price is now $997 per person
$997
per person
May 21 - May 25
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Syracuse (SYR)
8.4/10 Very Good! (1,004 reviews)
Nice clean rooms for a good price and close to the airport!

Reviewed on Apr 12, 2026

The Craftsman Inn & Suites

The Craftsman Inn & Suites

3.5 out of 5
Price was $636, price is now $533 per person
$533
per person
Jul 5 - Jul 8
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Syracuse (SYR)
9.4/10 Exceptional! (1,386 reviews)
Clean room, updated. Hallways are old school. All staff we encountered were great and friendly!

Reviewed on Apr 11, 2026

Syracuse Grand

Syracuse Grand

2.5 out of 5
Price was $513, price is now $433 per person
$433
per person
Jul 5 - Jul 8
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Syracuse (SYR)
6.6/10 (1,004 reviews)
Room was dirty. No bedding for pull out. Staff was nice. Pool and hot tub were excellent. Breakfast was horrible.

Reviewed on Apr 11, 2026

Staybridge Suites Liverpool Syracuse by IHG

Staybridge Suites Liverpool Syracuse by IHG

3 out of 5
Price was $643, price is now $550 per person
$550
per person
Jul 5 - Jul 8
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Syracuse (SYR)
8.8/10 Excellent! (694 reviews)
Clean room the staff were very nice & helpful i definitely would recommend

Reviewed on Feb 20, 2026

Where to stay in Downtown Syracuse

Find the best Downtown Syracuse areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Syracuse
Eastside

Eastside

2 out of top 10 points of interest in this area
3.5/5(31 area reviews)

Bordering Downtown Syracuse and University Hill, Near Eastside boasts historic gems like the Gustav Stickley House and Collins House. Explore the rich history while staying close to downtown attractions.

Find hotels in Eastside

Downtown Syracuse Hotel Deals

Marriott Syracuse Downtown

Marriott Syracuse Downtown

4 out of 5
100 East Onondaga Street Syracuse NY
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $177 total per night from Apr 26 to Apr 27
$177 total
Apr 26 - Apr 27
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
My room was large and comfortable. The tv was not working and they sent a person up to my room to fix it very quickly. But I found some seeds on the floor and tags in the bathroom that were not from my clothes. Overall I had a great time and would stay again though

Reviewed on Apr 12, 2026

Marriott Syracuse Downtown
Best Western Syracuse Downtown Hotel and Suites

Best Western Syracuse Downtown Hotel and Suites

3 out of 5
416 S Clinton St Syracuse NY
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $140 total per night from Apr 19 to Apr 20
$140 total
Apr 19 - Apr 20
Total with taxes and fees
8.4/10 Very Good! (646 reviews)
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Reviewed on Apr 16, 2026

Best Western Syracuse Downtown Hotel and Suites
Courtyard Syracuse Downtown At Armory Square

Courtyard Syracuse Downtown At Armory Square

3 out of 5
300 West Fayette Street Syracuse NY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Apr 26 to Apr 27
$149 total
Apr 26 - Apr 27
Total with taxes and fees
8.6/10 Excellent! (709 reviews)
Hotel was clean, parking you pay 19.00 per day but made it easy to park so worth it,

Reviewed on Apr 15, 2026

Courtyard Syracuse Downtown At Armory Square
See all 585 properties in Downtown Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Downtown Syracuse

Armory Square

Armory Square

Home to Syracuse’s highest concentration of bars and restaurants, this lively city square is the perfect place for a night out in Central New York.

Armory Square
Landmark Theatre

Landmark Theatre

See Broadway musicals, comedy or rock shows at this beautiful and supposedly haunted 1920s venue just off Syracuse’s Armory Square.

Landmark Theatre
Museum of Science and Technology

Museum of Science and Technology

Kids and adults will love this Syracuse museum, featuring an IMAX theater, interactive exhibits and possibly the world’s largest collection of toothpick sculptures.

Museum of Science and Technology

Things to do

1 Hour Walk-In Axe Throwing Experience Syracuse

1-Hour Walk-In Axe Throwing Experience Syracuse

$37
per adult
100% of travellers recommend
1-Hour Walk-In Axe Throwing Experience Syracuse
See all activities in Syracuse

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