Eastern Massachusetts Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Eastern Massachusetts Vacation

Choose one of our vacation packages to Eastern Massachusetts and wander wherever your inner adventurer desires. Dining and culture are just a couple of the things you can look forward to in this exciting destination. Your trip to Eastern Massachusetts wouldn't be complete without experiencing some of its most well-known cities, starting with Boston. Two of the top attractions here include Fenway Park and TD Garden. Hyannis is another favorite city with Eastern Massachusetts travelers. Visitors to this exciting destination enjoy Cape Codder Water Park and Cape Cod Inflatable Park. From the instant you book your Eastern Massachusetts vacation to when you get back home, Expedia will be with you each step of the way.

Where to stay in Eastern Massachusetts

Find the best Eastern Massachusetts areas and neighborhoods for the activities you enjoy most. Learn more about Eastern Massachusetts

Discover the most popular places to visit in Eastern Massachusetts

What to do in Eastern Massachusetts

Eastern Massachusetts Hotel Deals

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

4 out of 5
450 Summer Street, Boston, MA
$274 nightly
The price is $319 total per night from Oct 30 to Oct 31
$319 total
Oct 30 - Oct 31
Total with taxes and fees
9/10 Wonderful! (4,082 reviews)
"For our trip to Boston, this location worked out well! The hotel was comfortable, well appointed and had ample onsite parking. We were able to park the car and leave it for the 4 days-walked or took “the T” everywhere. Lots of restaurants nearby but the hotel also had really good options too!"

Reviewed on Sep 28, 2025

Omni Boston Hotel at the Seaport
citizenM Boston North Station

citizenM Boston North Station

4 out of 5
70 Causeway Street, Boston, MA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $267 total per night from Oct 5 to Oct 6
$267 total
Oct 5 - Oct 6
Total with taxes and fees
9.2/10 Wonderful! (3,858 reviews)
"Hotel was amazing"

Reviewed on Oct 2, 2025

citizenM Boston North Station
The Dagny Boston

The Dagny Boston

4 out of 5
89 Broad Street, Boston, MA
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $325 total per night from Oct 31 to Nov 1
$325 total
Oct 31 - Nov 1
Total with taxes and fees
9.4/10 Exceptional! (6,529 reviews)
"Hip and happening hotel. Financial district is a nice place. Coffee bar and restaurant in the lobby are great."

Reviewed on Oct 2, 2025

The Dagny Boston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Eastern Massachusetts Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Logan Intl. Airport (BOS)

More vacations you might like

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.