Main Street Fort Pierce, FL

Fort Pierce

A marina with boats, a bridge, and buildings along a waterfront.
A multi-story building with balconies and a palm tree in front.
A stone archway with the inscription "Melody Lane Fishing Pier" against a clear blue sky.
A person fishing by a waterfront with a railing and a view of buildings in the distance.
The entrance to the Naval Undersea Warfare Museum with a pathway leading to the building, a helicopter, and a boat.

Stay near popular Main Street Fort Pierce attractions

Sunrise Theater

8.4/10 (120 reviews)
You can enjoy a show at Sunrise Theater during your trip to Fort Pierce. Wander the waterfront and beautiful beaches in this culturally rich area.
See properties

Things to do

Clear Kayak Tours in Fort Pierce

Clear Kayak Tours in Fort Pierce

$90
per adult
Clear Kayak Tours in Fort Pierce
Yacht Charters & Custom Events in Stuart, Florida

Yacht Charters & Custom Events in Stuart, Florida

$130
per adult
Yacht Charters & Custom Events in Stuart, Florida
See all activities in Fort Pierce

Main Street Fort Pierce Hotel Deals

voco Sandpiper All-Inclusive Resort by IHG

voco Sandpiper All-Inclusive Resort by IHG

3.5 out of 5
4500 SE Pine Valley Street Port Saint Lucie FL
$335 nightly
The price is $375 total per night from Nov 11 to Nov 12
$375 total
Nov 11 - Nov 12
Total with taxes and fees
Stay at this resort in Port Saint Lucie. Enjoy free WiFi, 2 outdoor pools, and 3 restaurants. Popular attractions The Saints at Port St. Lucie Golf Course and ...
8.8/10 Excellent! (823 reviews)
"una atencion espectacular buena comida h una limpieza de primera"

Reviewed on Nov 10, 2026

voco Sandpiper All-Inclusive Resort by IHG
The Lucie

The Lucie

3 out of 5
10978 S Ocean Dr Jensen Beach FL
$210 nightly
The price is $235 total per night from Nov 15 to Nov 16
$235 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this beach hotel in Jensen Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,080 reviews)
"Great stay"

Reviewed on Nov 10, 2026

The Lucie
Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

4 out of 5
555 NE Ocean Boulevard Stuart FL
$206 nightly
The price is $230 total per night from Nov 23 to Nov 24
$230 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this beach hotel in Stuart. Enjoy free parking, 3 outdoor pools, and 3 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina
At Home Inn

At Home Inn

2.5 out of 5
7025 Okeechobee Road Fort Pierce FL
$56 nightly
The price is $63 total per night from Nov 11 to Nov 12
$63 total
Nov 11 - Nov 12
Total with taxes and fees
Stay at this motel in Fort Pierce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
At Home Inn
Hutchinson Island Hotel

Hutchinson Island Hotel

2.5 out of 5
1230 Seaway Drive Fort Pierce FL
$143 nightly
The price is $160 total per night from Nov 11 to Nov 12
$160 total
Nov 11 - Nov 12
Total with taxes and fees
Book a stay at this beach hotel in Fort Pierce. Enjoy free breakfast, free WiFi, and a private beach. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,374 reviews)
"Great place to stay"

Reviewed on Nov 9, 2026

Hutchinson Island Hotel
Vero Beach Inn & Suites I-95

Vero Beach Inn & Suites I-95

3 out of 5
8797 20th St Vero Beach FL
$58 nightly
The price is $65 total per night from Nov 28 to Nov 29
$65 total
Nov 28 - Nov 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Vero Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,756 reviews)
"I felt that the room wasn’t that clean. The walls were kind of dirty around the doors and it was the worst bathtub I’ve ever seen missing ceramic and coating! We also had some small bugs crawling around the room. I did not go to the breakfast, but my husband did and he said it was absolutely terrible! ..."

Reviewed on Nov 9, 2026

Vero Beach Inn & Suites I-95
See all 3,003 properties in Main Street Fort Pierce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.
A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, McKee Botanical Garden and Avalon State Park are some notable places to visit nearby.

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Harbor Branch Ocean Discovery Center and McKee Botanical Garden.

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

Main Street Fort Pierce, FL

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