
Main Street Fort Pierce Vacations from $378
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Main Street Fort Pierce Vacation
Say farewell to the hassle of planning and hello to a Main Street Fort Pierce vacation package. With everything organized before you take off, you can focus on discovering the best of this city, starting with Seagrove, which is good for cafes, coastal beaches and nature. If taking in sights is part of the program during your trip to Main Street Fort Pierce, check out top attractions like Sunrise Theater, Jetty Park and Fort Pierce Inlet State Park. Browse Expedia's extensive range of travel options and start organizing your dream vacation to Main Street Fort Pierce today.
The Latest Main Street Fort Pierce Vacation Packages

The Royal Inn Beach Hotel Hutchinson Island
Reviewed on Jul 6, 2026

Oaak Tree Hotel
Reviewed on Jun 20, 2026

Turtle Reef Club
Reviewed on Jun 26, 2026

SEVEN Sebring Raceway Hotel
Reviewed on Jul 8, 2026
Where to stay in Main Street Fort Pierce

Lakewood Park
While Lakewood Park isn't home to many top sights, Lakewood Park Regional Park / Pool and McKee Botanical Garden are some notable places to visit nearby.
Main Street Fort Pierce Hotel Deals

The Lucie
"great location and amenities"
Reviewed on Jul 11, 2026

voco Sandpiper All-Inclusive Resort by IHG
"Muy buena atención por parte del personal"
Reviewed on Jul 11, 2026

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina
"The room and overall property was amazing. The staff went above and beyond to ensure our stay was incredible. The room location and all the amenities were spot on. I couldnt have asked for a better vacation property. I will definitely be booking additional stays in the future."
Reviewed on Jul 10, 2026
Stay near popular Main Street Fort Pierce attractions
Things to do

6-Hr Tropical Mangroves, Coastal River and Ocean Wildlife Watch

Fort Pierce: 8-hr Jungle and Lagoon passage to Ocean in FL
Explore a world of travel with Expedia
- Hotels with Restaurants in Fort Pierce
- Cheap Hotels in Port Saint Lucie
- Cabin Rentals in Fort Pierce
- Casino Hotels in Fort Pierce
- Hotels near Jetty Park Beach
- Hotels with Hot Tubs in Fort Pierce
- Motels in Fort Pierce
- Oceanfront Hotels in Palm Beach
- Resorts & Hotels with Spas in Fort Pierce
- Luxury Hotels in Fort Pierce
- West Palm Beach Hotels
- Jupiter Hotels
- Hotels near Sunrise Theater
- Cheap Hotels in Fort Pierce
- Oceanfront Hotels in Hutchinson Island
- Port Saint Lucie Hotels
- Beach Hotels in Fort Pierce
- Marriott Hotels & Resorts in Fort Pierce
- Apartments in Fort Pierce
- Stuart Hotels
- Vero Beach Hotels
- Oceanfront Hotels in Vero Beach
- Melbourne Hotels
- Hotels with Kitchenettes in Fort Pierce
- Pet-Friendly Hotels in Fort Pierce
- Oceanfront Hotels in Fort Pierce
- Fort Pierce Hotels
- Jensen Beach Hotels
- Flights from Fort Pierce
- Flights to Jensen Beach
- Flights from Orlando (MCO) to Fort Pierce (FPR)
- Flights from Stuart
- Flights to Port Saint Lucie
- Flights from New York (NYC) to West Palm Beach (PBI)
- Flights to Stuart
- Flights from Palm Beach Intl.
- Flights from Vero Beach
- Flights to Melbourne
- Flights from Newark Liberty Intl. Airport (EWR) to West Palm Beach (PBI)
- Flights from Port Saint Lucie
- Flights to Hutchinson Island
- Flights from Boston (BOS) to West Palm Beach (PBI)
- Flights to Vero Beach
- Flights from Vero Beach Municipal
- Flights to Treasure Coast
- Flights to Fort Pierce
- Flights to West Palm Beach
- Flights from New York (NYC) to Vero Beach (VRB)
- Flights from Saint Lucie County Intl.
- Flights to Palm Beach
- Flights from Boston (BOS) to Vero Beach (VRB)
- Federal Mall
- Little Jim Bridge Park
- John B. Park Sports Complex
- Fort Pierce Vacations
- Visit Fort Pierce
- Bear Point Sanctuary
- Fort Pierce City Marina
- Harbour Pointe Park
- Pepper Park Beachside
- Heathcote Botanical Gardens
- House of Seven Gables
- St. Lucie County Regional History Center
- Manatee Education and Observation Center
- Downtown Fort Pierce
- Visit Port Saint Lucie
- Havert L. Fenn Center
- Jetty Park Beach
- Mar-A-Lago
- Fort Pierce Inlet State Park
- The National Navy UDT-SEAL Museum
- Causeway Cove
- Official Highwaymen Art Gallery
- John Brooks Park Riverside
- Riverside Marina
- St. Lucie County Aquarium
- Jetty Park
- Mckee Botanical Garden
- Museum Pointe Park
- Ilous Ellis Park / Pool
- Horatio Grisby Park
- North Causeway Island Park
- Jensen Beach to Jupiter Inlet Aquatic Preserve
- Car rental Fort Pierce
- Budget Rental Cars in Fort Pierce
- Car rental Vero Beach
- Avis Rental Cars in Fort Pierce
- Rental cars Palm Beach Intl. airport
- Car rental West Palm Beach
- Car rental Port Saint Lucie
- Enterprise Rental Cars in Fort Pierce
- Car rental Melbourne
- Hertz Rental Cars in Fort Pierce
- Car rental Stuart
























