Main Street Fort Pierce Vacations from $238

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Your Main Street Fort Pierce Vacation

Say farewell to the hassle of planning and hello to a Main Street Fort Pierce vacation package. With everything organized before you take off, you can focus on discovering the best of this city, starting with Seagrove, which is good for cafes, coastal beaches and nature. If taking in sights is part of the program during your trip to Main Street Fort Pierce, check out top attractions like Sunrise Theater, Jetty Park and Fort Pierce Inlet State Park. Browse Expedia's extensive range of travel options and start organizing your dream vacation to Main Street Fort Pierce today.

The Latest Main Street Fort Pierce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Roland Martin Marina and Resort
Oak Tree Hotel
La Quinta Inn & Suites by Wyndham Sebring
Sebastian Saltwater Lodge
Palm Breeze Lux Stay - Port St. Lucie

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most. Learn more about Main Street Fort Pierce

Main Street Fort Pierce Hotel Deals

Marriott Hutchinson Island Beach Resort, Golf & Marina

Marriott Hutchinson Island Beach Resort, Golf & Marina

3.5 out of 5
555 NE Ocean Boulevard, Stuart, FL
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $202 total per night from Sep 1 to Sep 2
$202 total
Sep 1 - Sep 2
Total with taxes and fees
8/10 Very Good! (290 reviews)
"Loved our time here. It was clean and comfortable."

Reviewed on Aug 21, 2025

Marriott Hutchinson Island Beach Resort, Golf & Marina
At Home Inn

At Home Inn

2.5 out of 5
7025 Okeechobee Road, Fort Pierce, FL
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $66 total per night from Aug 25 to Aug 26
$66 total
Aug 25 - Aug 26
Total with taxes and fees
7.6/10 Good! (1,000 reviews)
"the staff are super nice, all clean....AAAA ++++"

Reviewed on Aug 19, 2025

At Home Inn
Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach

3.5 out of 5
3384 Ocean Dr, Vero Beach, FL
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $133 total per night from Aug 27 to Aug 28
$133 total
Aug 27 - Aug 28
Total with taxes and fees
8.6/10 Excellent! (1,015 reviews)
"Friendly staff right on beach"

Reviewed on Aug 19, 2025

Ocean Breeze Inn Vero Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Main Street Fort Pierce

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.