Find hotels in Grand Isle, Port St. Joe

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Our top choices for Grand Isle hotels

Candlewood Suites Panama City Tyndall AFB by IHG

Candlewood Suites Panama City Tyndall AFB by IHG
2.5 star property
17.8 mi from Grand Isle
9.6 out of 10, Exceptional, (33)
"The room was great, the staff was friendly and helpful. "
United States
Robert
$94 nightly
The price is $101
Dec 24 - Dec 25
Total with taxes and fees
Candlewood Suites Panama City Tyndall AFB by IHG

Days Inn by Wyndham Panama City/Callaway

Days Inn by Wyndham Panama City/Callaway
2.0 star property
18.3 mi from Grand Isle
6.8 out of 10, (477)
"Room was clean and the staff was friendly and helpful."
United States
Billie
$56 nightly
The price is $60
Dec 18 - Dec 19
Total with taxes and fees
Days Inn by Wyndham Panama City/Callaway

MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South
2.5 star property
13.7 mi from Grand Isle
8.6 out of 10, Excellent, (694)
"Room was clean, kitchen very clean, hotel staff was very friendly "
United States
Donna
$110 nightly
The price is $123
Dec 28 - Dec 29
Total with taxes and fees
MainStay Suites Port Saint Joe South

Comfort Suites

Comfort Suites
2.5 star property
18 mi from Grand Isle
8.6 out of 10, Excellent, (715)
"The staff I encountered were polite and very helpful."
United States
Gerard
$85 nightly
The price is $91
Jan 1 - Jan 2, 2026
Total with taxes and fees
Comfort Suites

Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway
2.5 star property
18.7 mi from Grand Isle
6.2 out of 10, (494)
"great stay"
United States
Victor
$68 nightly
The price is $73
Dec 28 - Dec 29
Total with taxes and fees
Extended Stay America Select Suites - Panama City - Callaway

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
2.5 star property
18.1 mi from Grand Isle
8.4 out of 10, Very Good, (445)
"We enjoyed our stay."
United States
Lisa
$96 nightly
The price is $103
Dec 18 - Dec 19
Total with taxes and fees
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

The Port Inn and Cottages, an Ascend Collection Hotel

The Port Inn and Cottages, an Ascend Collection Hotel
3.5 star property
Downtown Port St. Joe, 11.1 mi from Grand Isle
9.0 out of 10, Wonderful, (404)
"Great staff, clean and comfortable room "
United States
Karen
$130 nightly
The price is $146
Jan 15 - Jan 16, 2026
Total with taxes and fees
The Port Inn and Cottages, an Ascend Collection Hotel

Cape San Blas Inn

Cape San Blas Inn
3.0 star property
16.8 mi from Grand Isle
9.8 out of 10, Exceptional, (79)
"Great host excellent location we will be back"
United States
Tonianne
$334 nightly
The price is $374
Dec 16 - Dec 17
Total with taxes and fees
Cape San Blas Inn

Cape Cottages by Panhandle Getaways

Cape Cottages by Panhandle Getaways
3.5 star property
14.2 mi from Grand Isle
10.0 out of 10, Exceptional, (4)
"Brand new, quaint spot with really comfortable beds. "
United States
Anonymous traveler
$483 nightly
The price is $542
Dec 17 - Dec 18
Total with taxes and fees
Cape Cottages by Panhandle Getaways
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.

Cape Breezes

While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.

Gulf Aire

While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.

Waterside Village

Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Top Grand Isle Hotel Reviews

Frequently asked questions

What is Grand Isle like?
Travelers to Mexico Beach's Grand Isle neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels will I find in Grand Isle?
Expedia has 7 Grand Isle hotels and other accommodations, and one might make a good home base for venturing out into the greater Mexico Beach area.
If I need to cancel my hotel reservation in Grand Isle, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Isle.
Where can I learn more about changing or cancelling my trip to Grand Isle?
For more details about rescheduling or cancelling your trip to Grand Isle, go to https://www.expedia.com/service/.
What is there to do around this Mexico Beach neighborhood?
Mexico Beach Business Center, Mexico Beach, and Mexico Beach Marina are just a few of the places to visit in and around Grand Isle. When you're sightseeing around the area, Saint Joe Beach and Round Timber Island are a couple of other sights to visit.

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