Greenville Vacations from $299

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Greenville Vacation

When a getaway to the city is calling, answer it with a Greenville vacation package. The neighborhood of SoBro, which is good for cafes, bars and pubs and nightlife, makes an awesome base for your adventures. Hoping to do a little sightseeing? Spend some time exploring major attractions like Marrowbone Lake during your trip to Greenville. A few quick clicks is all it takes to build your dream Greenville vacation on Expedia.

The Latest Greenville Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Nashville Airport Marriott
The Gilmore, an AvantStay Hotel
Bode Nashville
1 Hotel Nashville
Margaritaville Vacation Club Nashville

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.

Where to stay in Greenville

Find the best Greenville areas and neighborhoods for the activities you enjoy most. Learn more about Greenville

Greenville Hotel Deals

Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

4 out of 5
2800 Opryland Drive Nashville TN
Fully refundableReserve now, pay when you stay
$352 nightly
The price is $414 total per night from Dec 14 to Dec 15
$414 total
Dec 14 - Dec 15
Total with taxes and fees
8.6/10 Excellent! (1,739 reviews)
Beautiful

Reviewed on Nov 25, 2025

Gaylord Opryland Resort & Convention Center
Comfort Inn Downtown Nashville - Music City Center

Comfort Inn Downtown Nashville - Music City Center

3 out of 5
1501 Demonbreun St Nashville TN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $95 total per night from Nov 30 to Dec 1
$95 total
Nov 30 - Dec 1
Total with taxes and fees
8/10 Very Good! (3,196 reviews)
Clean room, great breakfast, staff extremely nice and helpful. Easy parking ( but charged a fee) but guess that the thing in Nashville every where you go are parking fees. It’s just the norm. We truly enjoy our stay. A nice little place amongst tge skyscrapers! Would highly recommend it!

Reviewed on Nov 25, 2025

Comfort Inn Downtown Nashville - Music City Center
Hyatt House Nashville Downtown/Convention Center

Hyatt House Nashville Downtown/Convention Center

3 out of 5
535 Rep. John Lewis Way S Nashville TN
$121 nightly
The price is $144 total per night from Dec 17 to Dec 18
$144 total
Dec 17 - Dec 18
Total with taxes and fees
8.8/10 Excellent! (2,489 reviews)
Room was clean. Staffs were friendly. Walking distance to Honky Tonk Highway and most of the museums. A good stay.

Reviewed on Nov 27, 2025

Hyatt House Nashville Downtown/Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Greenville

Things to do

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.