Greenville Vacations from $621

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Your Greenville Vacation

When a getaway to the city is calling, answer it with a Greenville vacation package. The neighborhood of SoBro, which is good for cafes, bars and pubs and nightlife, makes an awesome base for your adventures. Hoping to do a little sightseeing? Spend some time exploring major attractions like Marrowbone Lake during your trip to Greenville. A few quick clicks is all it takes to build your dream Greenville vacation on Expedia.

The Latest Greenville Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Margaritaville Hotel Nashville
Bobby Hotel
The Carter by AvantStay – Spacious Stay Near Downtown 
1 Hotel Nashville
121 Hotel Floor 3 Buyout by Avantstay Entire Third Floor Buyout of 121 Hotel! Sleeps 18

Where to stay in Greenville

Find the best Greenville areas and neighborhoods for the activities you enjoy most. Learn more about Greenville

Greenville Hotel Deals

Knights Inn Nashville

Knights Inn Nashville

1.5 out of 5
99 Spring St, Nashville, TN
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $79 total per night from Jul 16 to Jul 17
$79 total
Jul 16 - Jul 17
Total includes taxes and fees
7.6/10 Good! (349 reviews)
"The facility and bedroom was very clean. John is very cordial with the customers. It was very comfortable. The towels was changed daily. It was wll equipped. I recommend it!!!!"

Reviewed on Jul 14, 2025

Knights Inn Nashville
Comfort Inn Downtown Nashville - Music City Center

Comfort Inn Downtown Nashville - Music City Center

3 out of 5
1501 Demonbreun St, Nashville, TN
$98 nightly
The price is $117 total per night from Jul 28 to Jul 29
$117 total
Jul 28 - Jul 29
Total includes taxes and fees
7.8/10 Good! (2,444 reviews)
"I’m happy"

Reviewed on Jul 15, 2025

Comfort Inn Downtown Nashville - Music City Center
Gaylord Opryland Resort & Convention Center

Gaylord Opryland Resort & Convention Center

4 out of 5
2800 Opryland Drive, Nashville, TN
Fully refundableReserve now, pay when you stay
$377 nightly
The price is $443 total per night from Jul 31 to Aug 1
$443 total
Jul 31 - Aug 1
Total includes taxes and fees
8.6/10 Excellent! (1,677 reviews)
"Just a great time and once you parked your car you didn’t have to leave till it was time"

Reviewed on Jul 14, 2025

Gaylord Opryland Resort & Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Greenville

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.