Guadalupe Vacations from $401

Book a Hotel + Flight or Car together to unlock savings

Photo by robb image

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Guadalupe Vacation

With one of our vacation packages to Guadalupe, you'll have infinite opportunities for adventure and relaxation. There's loads to experience, including its rich history and cultural experiences. When the time comes to get out and see the sights, be sure to put Guadalupe-Nipomo Dunes and Point Sal State Beach on the itinerary for your trip to Guadalupe. Don't delay visiting this destination any longer. The perfect Guadalupe vacation is a few clicks away with Expedia.

The Latest Guadalupe vacation packages

Price found within the past 48 hours. Click for updated prices.
Blufftop Inn & Suites - Wharf/Restaurant District

Blufftop Inn & Suites - Wharf/Restaurant District

2 out of 5
Price was $604, price is now $401 per person
$401
per person
Nov 14 - Nov 18
found 8 hours ago
Roundtrip non-stop flight included
Denver (DEN) to San Luis Obispo (SBP)
9.2/10 Wonderful! (929 reviews)
The room was super cute and updated. The staff was really nice. The only downside was the super thin walls. It sounded like a grizzly bear in cement shoes was in the room above us. Not only loud clomping feer back and forth but the snoring sounded like he was in the same room with us.

Reviewed on Sep 19, 2025

Spyglass Inn

Spyglass Inn

3 out of 5
Save 100% on your flight
Price was $733, price is now $511 per person
$511
per person
Nov 14 - Nov 18
found 6 hours ago
Roundtrip non-stop flight included
Denver (DEN) to San Luis Obispo (SBP)
9/10 Wonderful! (1,233 reviews)
I loved the view from our room. It was very calming. The bed was so comfortable and room was clean.

Reviewed on Sep 27, 2025

Wine Country Estate w/ Pool, Hot Tub The Residence at Truss Wines by Avantstay

Wine Country Estate w/ Pool, Hot Tub The Residence at Truss Wines by Avantstay

3 out of 5
Save 100% on your flight
Price was $5,144, price is now $3,602 per person
$3,602
per person
Dec 12 - Dec 15
found 1 hour ago
Roundtrip flight included
Denver (DEN) to San Luis Obispo (SBP)
No reviews
Rancho Robles by Avantstay Vineyard Villa w/ Views, Pool & Privacy

Rancho Robles by Avantstay Vineyard Villa w/ Views, Pool & Privacy

3.5 out of 5
Save 100% on your flight
Price was $4,647, price is now $3,270 per person
$3,270
per person
Dec 12 - Dec 15
found 1 hour ago
Roundtrip flight included
Denver (DEN) to San Luis Obispo (SBP)
No reviews
Victorian Manor In Paso Robles Wine Country + Pool, Hot Tub, Firepit, Tennis Court Sleeps 28

Victorian Manor In Paso Robles Wine Country + Pool, Hot Tub, Firepit, Tennis Court Sleeps 28

3 out of 5
Save 100% on your flight
Price was $5,338, price is now $3,771 per person
$3,771
per person
Dec 12 - Dec 15
found 1 hour ago
Roundtrip flight included
Denver (DEN) to San Luis Obispo (SBP)
No reviews
Don't see what you're looking for?
See all available trips from Columbus to Guadalupe
View all trips

Discover the most popular places to visit in Guadalupe

Guadalupe-Nipomo Dunes

Explore the great outdoors at Guadalupe-Nipomo Dunes, a lovely green space in Guadalupe. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.

Guadalupe-Nipomo Dunes

Guadalupe Hotel Deals

SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

3.5 out of 5
2241 Price Street, Pismo Beach, CA
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $217 total per night from Oct 13 to Oct 14
$217 total
Oct 13 - Oct 14
Total with taxes and fees
9/10 Wonderful! (1,578 reviews)
"Clean, quiet, and relaxing accommodations. Staff friendly and helpful. Spa jets need maintenance and proper towel restocking would be helpful. Enjoyed beach front property and ability to walk to pier. Overall very relaxing."

Reviewed on Sep 24, 2025

SeaCrest OceanFront Hotel
Sandcastle Hotel on the Beach

Sandcastle Hotel on the Beach

3.5 out of 5
100 Stimson Ave, Pismo Beach, CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $187 total per night from Oct 15 to Oct 16
$187 total
Oct 15 - Oct 16
Total with taxes and fees
8.8/10 Excellent! (1,484 reviews)
"It was such a peaceful few days staying here and there coffee was amazing!"

Reviewed on Sep 24, 2025

Sandcastle Hotel on the Beach
Cottage Inn By The Sea

Cottage Inn By The Sea

3 out of 5
2351 Price St, Pismo Beach, CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $149 total per night from Oct 8 to Oct 9
$149 total
Oct 8 - Oct 9
Total with taxes and fees
8.8/10 Excellent! (1,114 reviews)
"The floor LOOKS clean because of the laminate, but it is dirty. I wiped a small area with a tissue to pick up something, and the tissue was black. Also, my husband is sensitive to particulates in the air (dust, etc.). His nose continually ran except when he was in the hot tub and when we went to ..."

Reviewed on Sep 23, 2025

Cottage Inn By The Sea
See all 1,027 properties in Guadalupe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Guadalupe vacation package cost?
You'll find cheap prices from $401 on Expedia for your Guadalupe escape. However, factors like the season, length of stay and your choice of hotel will determine how much your vacation to Guadalupe costs.
What are the cheapest months to go to Guadalupe?
You're likely to find lower rates and better availability in September, October and December. Take a look at our cheap Guadalupe vacation packages and you could land some great off-season deals.
How many days is enough for Guadalupe?
Generally, a handful of days is enough to see the major attractions during your Guadalupe vacation. But if you prefer to have more time to rest or go on day tours, think about extending your itinerary.
How to find the best Guadalupe package deals?
Use Expedia's filter tool to find some unbeatable Guadalupe package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Guadalupe package deals in the off-peak season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as soon as possible.
Is it cheaper to book a Guadalupe vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll typically score a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Guadalupe vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Guadalupe?
If you have your Guadalupe travel dates locked in, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for traveling on a whim.
Does Expedia offer Book Now, Pay Later Guadalupe vacation packages?
Your Guadalupe getaway should be an escape from your daily routine, not a source of money worries. So to allow you a bit more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.