Isla Grande Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Nov 21 - Nov 23
In two months
Jan 2 - Jan 4
In three months
Jan 30 - Feb 1
In four months
Feb 27 - Mar 1

Vacation Rentals in Isla Grande

Beach
Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province

Colón Province
$300 nightly
The price is $300
Nov 11 - Nov 12
Total with taxes and fees
Deluxe Beachfront 4-bedroom house in Colón Province
Villa, Private Pool | Outdoor pool | Indoor pool, outdoor pool
Brother Sun Villas

Brother Sun Villas

3.0 star property
Isla Grande
3.0 out of 10, (2)
"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"
United States
David
Brother Sun Villas
Beach
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

Maria Chiquita
5.0 out of 10, (2)
"Beach is the only activity. Beach was lovely, it is not the ocean’s fault the host-owners were so “don’t care”"
United States
Paul G
$155 nightly
The price is $155
Nov 10 - Nov 11
Total with taxes and fees
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Outdoor pool
Spacious Beach House on the ocean front with huge pool and patio.

Spacious Beach House on the ocean front with huge pool and patio.

Republic de Panama - Guanche - Colon - P
8.0 out of 10, Very Good, (7)
"Mr. Robert was extremely attentive "
United States
noris a.
Spacious Beach House on the ocean front with huge pool and patio.
Exterior
Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!

Colón Province
$171 nightly
The price is $171
Nov 10 - Nov 11
Total with taxes and fees
Cabaña La Punta op het Strand!!
Property grounds
Caribbean Beach House with Pool

Caribbean Beach House with Pool

Mechi
10.0 out of 10, Exceptional, (1)
"This property was well kept and managed, even with a few glitches the property owners were very responsive. It’s a peaceful environment we wouldn’t hesitate to visit again."
United States
Sulipsa L.
Caribbean Beach House with Pool
Free WiFi, bed sheets
Piscina Mar en el Paraíso Caribe

Piscina Mar en el Paraíso Caribe

Maria Chiquita
8.8 out of 10, Excellent, (3)
"Staff, especially William, was helpful. The elevator did not work for a couple of days and 8th floor was a bit of a walk. The driveway access is in a really poor condition. The room was just fine. "
Canada
Stan
Piscina Mar en el Paraíso Caribe
On the beach, sun loungers, beach towels
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Santa Isabel
10.0 out of 10, Exceptional, (30)
"A beautiful beachfront property with hammocks, snorkeling, kayaks and a lovely staff to prepare meals made this the ideal location for our family Christmas holiday."
United States
Celia P.
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Beach
Casa Frente al Mar - Isla Grande

Casa Frente al Mar - Isla Grande

Provincia de Colón
10.0 out of 10, Exceptional, (1)
"All perfect "
United States
alberto
Casa Frente al Mar - Isla Grande
Pool
Perfect getaway to the sea - Family apartment in exclusive Resort

Perfect getaway to the sea - Family apartment in exclusive Resort

María Chiquita
10.0 out of 10, Exceptional, (1)
"This was the best stay we encounter in a long time. The host was amazing, the apartment was immaculate, and the location was second to none. We had so much fun and the kids had a great time in a long time. Well recommended "
United States
Jorge R.
Perfect getaway to the sea - Family apartment in exclusive Resort
On the beach, sun loungers, beach towels
Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand

Palenque
10.0 out of 10, Exceptional, (1)
"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "
United States
Beth N.
$297 nightly
The price is $297
Nov 11 - Nov 12
Total with taxes and fees
Caribbean getaway: beach cottage just on the sand
Terrace/patio
Pebos Reef with amazing terrace over the sea - apartment #1

Pebos Reef with amazing terrace over the sea - apartment #1

Juan Gallego
Pebos Reef with amazing terrace over the sea - apartment #1
Outdoor pool
Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

María Chiquita
$502 nightly
The price is $502
Nov 14 - Nov 15
Total with taxes and fees
Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual
Outdoor dining
Kasa Leilani, the perfect Caribbean gateway!

Kasa Leilani, the perfect Caribbean gateway!

Juan Gallego
Kasa Leilani, the perfect Caribbean gateway!
Pool
Caribbean Paradise - Beachfront Getaway

Caribbean Paradise - Beachfront Getaway

Palenque
$492 nightly
The price is $492
Nov 11 - Nov 12
Total with taxes and fees
Caribbean Paradise - Beachfront Getaway
Outdoor dining
Nice house in Portobelo, Skybluebyguanche

Nice house in Portobelo, Skybluebyguanche

Portobelo
10.0 out of 10, Exceptional, (1)
"Very authentic experience. Right on beach, close to restaurants and Porto Belo. Host is easy to communicate with, very responsive. Place is very basic, safe, and cannot beat the location."
United States
Daniel K.
Nice house in Portobelo, Skybluebyguanche
Marina
Cara al mar Cacique

Cara al mar Cacique

Cacique
10.0 out of 10, Exceptional, (1)
"Rachel (the property owner) is the BEST! The car I rented couldn’t get up the steep driveway and she was there immediately to offer help. The views from the house are spectacular. We spent most of our time outside because there is a nice breeze off the ocean. I can hear howler monkeys. "
United States
Marie B.
Cara al mar Cacique
Property grounds
Casa Anzuelo is an oceanfront home that is all about the water and nature.

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Portobelo
10.0 out of 10, Exceptional, (16)
"The house and the property were very well managed, the accommodations also met my needs very well. Casa Anzuelo is a place to escape from the world, so if your goal is a peaceful place to read, think and enjoy the ocean & the warmth of the weather, then this is the place for you. Jim, the owner, was great to speak with regarding everything in the area as well as the background and history of Panama, and was willing to assist or help in anything that you needed. A great host!"
United States
Robert P.
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Terrace/patio
A fantastic place between the sea and the jungle

A fantastic place between the sea and the jungle

Colon
10.0 out of 10, Exceptional, (4)
"La comunicación con los anfitriones siempre fue buena, siempre atentos, recibíamos respuesta inmediata a cualquier consulta. La atencion muy buena, Chente y Laura estaban atentos a todo lo que se necesitara. Lindas vistas y muy cómodas las cabañas. Recomendado!!"
United States
Osvaldo G.
A fantastic place between the sea and the jungle
Marina
Despierta sobre el mar

Despierta sobre el mar

2.0 star property
Garrote
6.0 out of 10, (1)
$100 nightly
The price is $108
Nov 11 - Nov 12
Total with taxes and fees
Despierta sobre el mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Isla Grande Hotel Reviews

Piscina Mar en el Paraíso Caribe

Piscina Mar en el Paraíso Caribe

6/10 Okay
"Staff, especially William, was helpful. The elevator did not work for a couple of days and 8th floor was a bit of a walk. The driveway access is in a really poor condition. The room was just fine. "
Stan 10-night trip
Posted 10 days ago
Piscina Mar en el Paraíso Caribe

Find out more about Isla Grande

Everything you need to know about Isla Grande vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isla Grande vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isla Grande vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isla Grande vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isla Grande. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Isla Grande in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $108 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Isla Grande rentals

At Expedia, we put the best Isla Grande vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isla Grande rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isla Grande vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isla Grande. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Isla Grande?

Yes, we have vacation rentals near top sights in Isla Grande, or you can select a more secluded option if you'd like a relaxing place to stay. Isla Grande is known for its parks.

What are some of the best vacation home rentals in Isla Grande?

Deluxe Beachfront 4-bedroom house in Colón Province: This Isla Grande vacation home rental has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Isla Grande?

With 4 Expedia vacation rentals, you're sure to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Playa La Angosta and Portobelo National Park.

What are vacation rentals like in Isla Grande?

Vacation rentals are private properties you can stay in for several days or more in Isla Grande. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family gatherings.