Isla Grande Vacation Rentals

Check prices for these dates

Tonight
Aug 6 - Aug 7
Tomorrow
Aug 7 - Aug 8
This weekend
Aug 8 - Aug 10
Next weekend
Aug 15 - Aug 17

Vacation Rentals in Isla Grande

Brother Sun Villas
Villa, Private Pool | Outdoor pool | Indoor pool, outdoor pool

Brother Sun Villas

3.0 star property
3.0 out of 10, (2)
"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"
Brother Sun Villas
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Enjoy a serene beach experience with palm trees and a sandy shore.

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10.0 out of 10, Exceptional, (30)
"The property was stunning and the staff was amazing. Every meal prepared by the staff was better than the next. "
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Spacious Beach House on the ocean front with huge pool and patio.
Enjoy a refreshing swim in the pool surrounded by lush greenery and access to the beach.

Spacious Beach House on the ocean front with huge pool and patio.

8.0 out of 10, Very Good, (6)
"Very spacious and comfortable home…the best part was the pool and the view! Very safe complex, super attentive and responsive staff (Maria was great!). Everything in the home worked properly and the entire process from booking to checking out was very smooth. Definitely recommend!."
Spacious Beach House on the ocean front with huge pool and patio.
Cabaña La Punta op het Strand!!
La Casa de la Playa offers a two-story retreat on a tranquil waterway, surrounded by palm trees and a sandy beach.

Cabaña La Punta op het Strand!!

$171 nightly
The price is $171
Aug 7 - Aug 8
Total includes taxes and fees
Cabaña La Punta op het Strand!!
Piscina Mar en el Paraíso Caribe
Relax in this stylish room with a large sliding door to the pool area, a comfortable bed, and a seating area with a cushioned bench.

Piscina Mar en el Paraíso Caribe

10.0 out of 10, Exceptional, (2)
"Muy tranquilo durante la semana. Muy amable en personal"
Piscina Mar en el Paraíso Caribe
Casa Dinis - Casa Grande - Centro DE Portobelo
Enjoy a balcony with views of the surrounding area from this two-story building.

Casa Dinis - Casa Grande - Centro DE Portobelo

$596 nightly
The price is $596
Aug 7 - Aug 8
Total includes taxes and fees
Casa Dinis - Casa Grande - Centro DE Portobelo
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Enjoy a serene beachside setting with palm trees and a grassy area.

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

8.0 out of 10, Very Good, (1)
"It was good but check in was late due to cleaning crew and 1 of the AC was not working and the road into the property needs to be paved."
$155 nightly
The price is $155
Aug 9 - Aug 10
Total includes taxes and fees
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Caribbean Beach House with Pool
Stunning residential building with a symmetrical facade and beautifully manicured garden.

Caribbean Beach House with Pool

10.0 out of 10, Exceptional, (1)
"This property was well kept and managed, even with a few glitches the property owners were very responsive. It’s a peaceful environment we wouldn’t hesitate to visit again."
Caribbean Beach House with Pool
Casa Dinis - Loft - CON Vistas Bahia DE Portobelo
Relax in a spacious room with a high ceiling, comfortable seating areas, and a balcony offering views of the surrounding landscape.

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

$443 nightly
The price is $443
Aug 7 - Aug 8
Total includes taxes and fees
Casa Dinis - Loft - CON Vistas Bahia DE Portobelo
Cara al mar Cacique
Enjoy serene waterfront views and easy access to sailboats in this tranquil marina setting.

Cara al mar Cacique

10.0 out of 10, Exceptional, (1)
"Rachel (the property owner) is the BEST! The car I rented couldn’t get up the steep driveway and she was there immediately to offer help. The views from the house are spectacular. We spent most of our time outside because there is a nice breeze off the ocean. I can hear howler monkeys. "
Cara al mar Cacique
Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual
Relax by the pool surrounded by palm trees and comfortable lounge chairs, with the ocean visible in the background.

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

$432 nightly
The price is $432
Aug 13 - Aug 14
Total includes taxes and fees
Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual
Nice house in Portobelo, Skybluebyguanche
Relax under the gazebo with ocean views, a hammock, and comfortable seating for two.

Nice house in Portobelo, Skybluebyguanche

10.0 out of 10, Exceptional, (1)
"Very authentic experience. Right on beach, close to restaurants and Porto Belo. Host is easy to communicate with, very responsive. Place is very basic, safe, and cannot beat the location."
Nice house in Portobelo, Skybluebyguanche
A fantastic place between the sea and the jungle
Relax in a serene outdoor space with a sofa and chairs, surrounded by trees and a wooden fence.

A fantastic place between the sea and the jungle

10.0 out of 10, Exceptional, (4)
"What a magical place. The grounds and the bungalows were immaculate. There were fresh tropical flower arrangements everywhere. The caretakers where helpful, friendly but never intrusive. The natural beauty and the isolation were wonderful."
A fantastic place between the sea and the jungle
Casa Frente al Mar - Isla Grande
Overlooking turquoise waters and coral reefs, this coastal area offers stunning views of the ocean and surrounding boats.

Casa Frente al Mar - Isla Grande

10.0 out of 10, Exceptional, (1)
"All perfect "
Casa Frente al Mar - Isla Grande
BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Relax on the beach with a clear view of the ocean, surrounded by lush greenery and a distant island.

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

4.0 out of 10, (1)
"The furnishings are worn. The second bedroom is only suitable for small children. The house is only a few metres from a busy main road with noisy traffic. The beach is unattractive. The water is too shallow for swimming. And the house is NOT in the “historic centre” of Portobelo, which is several kilometres away and consists of the ruins of a fort and a church. We were so disappointed we left after one night."
BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Caribbean Paradise - Beachfront Getaway
Relax by the ocean with a serene view from the poolside lounge chairs.

Caribbean Paradise - Beachfront Getaway

$485 nightly
The price is $485
Aug 7 - Aug 8
Total includes taxes and fees
Caribbean Paradise - Beachfront Getaway
Pebos Reef with amazing terrace over the sea - apartment #1
Relax in a serene lakeside setting surrounded by lush tropical plants and take in the breathtaking views of distant hills.

Pebos Reef with amazing terrace over the sea - apartment #1

Pebos Reef with amazing terrace over the sea - apartment #1
Despierta sobre el mar
Moored alongside a tranquil waterfront, this boat offers a serene retreat with a spacious cabin and large windows.

Despierta sobre el mar

2.0 star property
6.0 out of 10, (1)
$100 nightly
The price is $108
Aug 8 - Aug 9
Total includes taxes and fees
Despierta sobre el mar
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Stroll through lush gardens to a tranquil gated community with uniform homes.

Casa Anzuelo is an oceanfront home that is all about the water and nature.

10.0 out of 10, Exceptional, (16)
"We loved our stay at casa Anzuelo. Jim makes you feel very welcome. The house is simple but completely sufficient. Jim answers willingly all your questions and provides any help needed. We would definitly vome back."
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Paraiso de Ensueño Caribeño
Relax in a serene outdoor space surrounded by lush greenery and a thatched roof.

Paraiso de Ensueño Caribeño

10.0 out of 10, Exceptional, (2)
"If enjoy and appreciate nature this is a wonderful place. You have all the basics necessary for unforgettable stay. The local people are very nice and welcoming. The see is magnificent.! "
Paraiso de Ensueño Caribeño
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Grande Hotel Reviews

Ordovician Beach Resort

Ordovician Beach Resort

10/10 Excellent
"The Ordovician Hotel is a hidden gem on the peaceful west side of Isla Grande. From the moment we booked, the service was personal and seamless—thank you, Yohan! We were welcomed by name, greeted with a delicious tropical drink, and felt like cherished guests from start to finish. We stayed in the Peacock Room, which had stunning views of the pool, restaurant, and beach. The room was beautifully curated, with luxurious bedding, high-end amenities, and thoughtful touches like a handwritten welcome card. The food was phenomenal, fusing Panamanian flavors with Asian influences—fresh, flavorful, and unforgettable. Special thanks to Sebastián, Chef Stiven, and the entire team for making every meal a delight. The outdoor massage on the yoga deck overlooking the ocean was magical, and we loved relaxing in the sauna, cold plunge, and hammocks under shaded palapas. We even extended our stay an extra day! A heartfelt thank-you to Rick and Loan for their vision, presence, and commitment to uplifting Panamanian talent. This place is more than a hotel—it’s an experience of luxury, soul, and connection. "
Tanya 2-night trip
Posted 12 days ago
Ordovician Beach Resort

Frequently asked questions

Can I find vacation rentals in Isla Grande?

Yes, we have vacation rentals near top sights in Isla Grande, or you can select a more secluded option if you'd like a relaxing place to stay. Isla Grande is known for its parks.

What are some of the best vacation home rentals in Isla Grande?

Spacious Beach House on the ocean front with huge pool and patio.: You might want to consider this vacation home rental near Isla Grande, which is located on the beach and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

How many vacation rentals will I find in Isla Grande?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Playa La Angosta and Portobelo National Park.

What are vacation rentals like in Isla Grande?

Vacation rentals are private properties you can stay in for several days or more in Isla Grande. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family gatherings.