Isla Grande Vacations from $721

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Your Isla Grande Vacation

With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.

The Latest Isla Grande vacation packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,150, price is now $721 per person
$721
per person
Oct 11 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was $3,815, price is now $2,039 per person
$2,039
per person
Nov 13 - Nov 20
found 3 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
No reviews
Casa Fofo Family House

Casa Fofo Family House

3 out of 5
Price was $1,617, price is now $990 per person
$990
per person
Oct 11 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
No reviews
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Save 100% on your flight
Price was $1,533, price is now $968 per person
$968
per person
Nov 13 - Nov 20
found 3 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
9.4/10 Exceptional! (111 reviews)
The grounds where beautiful and the staff was so friendly.

Reviewed on Jul 19, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
Price was $1,953, price is now $1,288 per person
$1,288
per person
Nov 13 - Nov 20
found 3 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
9.4/10 Exceptional! (84 reviews)
Wow! This resort is absolutely amazing! Bekar went above and beyond for us! He even brought in a TV to the lobby so we could watch the NHL playoff game! Food is 10/10 as well. We will definitely go back!

Reviewed on May 18, 2025

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Isla Grande Hotel Deals

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande, Isla Grande, Colon
10/10 Exceptional! (2 reviews)
"The Ordovician Hotel is a hidden gem on the peaceful west side of Isla Grande. From the moment we booked, the service was personal and seamless—thank you, Yohan! We were welcomed by name, greeted with a delicious tropical drink, and felt like cherished guests from start to finish. We stayed in the ..."

Reviewed on Jul 25, 2025

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Ordovician Beach Resort
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira, Isla Grande, Provincia de Colón
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Sep 4 to Sep 5
$89 total
Sep 4 - Sep 5
Total with taxes and fees
10/10 Exceptional! (1 review)
"Very rustic place but food is delicious and staff is super friendly and willing to help."

Reviewed on Aug 17, 2025

Hotel Cocotal
Brother Sun Villas

Brother Sun Villas

3 out of 5
Camino Al Faro, Isla Grande
Wrong advertisement
"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do ..."

Reviewed on Oct 15, 2017

Get rates
Brother Sun Villas
See all 57 properties in Isla Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does an Isla Grande vacation package cost?
You'll find cheap prices from $721 on Expedia for your Isla Grande getaway. However, factors like the season, choice of hotel and length of stay will influence how much your vacation to Isla Grande costs.
What are the cheapest months to go to Isla Grande?
August, November and December are great times to search for cheap Isla Grande vacation packages. Opting to travel in quieter months means you can generally find lower prices on accommodations and flights.
How many days is enough for Isla Grande?
Generally, a handful of days is enough to check out the major attractions during your Isla Grande vacation. But if you prefer to have time to relax or go on day tours, think about extending your itinerary.
How to find the best Isla Grande package deals?
Bagging a cheap Isla Grande package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and browse what's available. You can customize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly Isla Grande package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book an Isla Grande vacation as a package?
You can enjoy significant savings on your Isla Grande getaway by booking a personalized vacation package. Check the "Package" heading, then select your destination and travel dates to view the best flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Isla Grande?
Secure incredible bargains by booking your flights in advance with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Isla Grande break.
How to plan a trip to Isla Grande?

  1. Pick your dates: What you'd like to do in Isla Grande and your preferred season will help you decide when to get away.
  2. Set a budget: Consider expenses such as transportation, flights and meals when calculating how much to save for your trip to Isla Grande. Then, select a hotel that fits your budget, whether that's a wallet-friendly option or a lavish getaway.
  3. Use Expedia's trip planning tool to discover Isla Grande: Research every part of your trip to Isla Grande with this handy planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Decide how long to go away for: Now that you know more about Isla Grande, you can work out the ideal length of your vacation. Put together a draft itinerary and give yourself enough time to cover everything you want to see.
  5. Bundle your airfare and accommodations: Once you've settled on your dates and duration, book the perfect Isla Grande vacation package for you.
  6. Book any day trips or activities: Now to the fun part — organizing everything you want to do and see. Explore some of the exciting things to do in Isla Grande and reserve your tickets early to save time (and maybe some cash too!).

Does Expedia offer Book Now, Pay Later Isla Grande vacation packages?
Your Isla Grande break should be a relaxing escape from your busy life, not a reason for money-related stress. So to give you more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.