
Madre de Dios Region Vacations & Trips from $864
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Your Madre de Dios Region Vacation
Choose one of our vacation packages to Madre de Dios Region and wander wherever your adventurous soul takes you. Hiking and nature are just a couple of the things you can look forward to in this wonderful destination. Start your trip to Madre de Dios Region by spending a few nights in Tambopata, one of the top cities here. Expedia has hotels, flights and all your other travel needs to help you curate your very own customized Madre de Dios Region vacation today.
The Latest Madre de Dios Region Vacation Packages

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Reviewed on Sep 9, 2025

Inotawa Lodge
Reviewed on May 19, 2025
1. Escape to Tambopata with a vacation package
Tambopata in the Madre de Dios Region of Peru offers a unique outdoor vacation experience. With its lush jungle and rainforest, it provides the perfect setting for adventure and exploration. Visitors can enjoy activities such as hiking, wildlife spotting, and exploring natural parks. The region is known for its diverse wildlife and stunning natural beauty. Families will find plenty of family-friendly activities to enjoy, and there are also dining options available to satisfy any palate. Whether it's destination activities, tours, or sightseeing, Tambopata offers a memorable outdoor vacation for all.
- The peak season is from July to September
- The off-peak season is from November to January
- Travelers tend to stay 3 days in Tambopata
2. Create memories in Puerto Maldonado with a vacation package
Puerto Maldonado, located in the Madre de Dios Region of Peru, offers a unique outdoor vacation experience. With its lush jungles, majestic rivers, and picturesque lakes, this destination is perfect for nature enthusiasts. Visitors can enjoy boating tours, birdwatching, and exploring the vast rainforests. For those seeking a touch of luxury, there are upscale accommodations available. Puerto Maldonado is a haven for adventure seekers, offering activities such as hunting and sightseeing tours. Immerse yourself in the local atmosphere and experience the beauty of this vibrant city.
- The peak season is from January to March
- The off-peak season is from October to December
- Travelers tend to stay 2 days in Puerto Maldonado
3. Experience Las Piedras with a travel package
Las Piedras in the Madre de Dios Region of Peru offers a stunning atmosphere for outdoor vacations. Immerse yourself in the lush rainforests and explore the vast biodiversity of the Amazon. Go on thrilling adventures like jungle hikes, wildlife spotting, and canoeing along the rivers. Experience the local culture by visiting nearby indigenous communities and learning about their traditions. Stay in eco-lodges and enjoy the tranquility of the surroundings. Whether you're a nature enthusiast or an adventure seeker, Las Piedras offers an unforgettable outdoor vacation experience.
- Travelers tend to stay 3 days in Las Piedras
4. Find your perfect Manu vacation
Manu, located in the Madre de Dios Region of Peru, offers a unique outdoor vacation experience. The region's geographic affinities make it perfect for natural parks and wildlife conservation. Visitors to Manu can immerse themselves in destination activities, such as guided tours and sightseeing, that allow them to explore the stunning natural beauty of the area. Whether it's trekking through the lush rainforests, spotting exotic wildlife, or visiting indigenous communities, Manu provides an authentic and unforgettable outdoor adventure for travelers from the United States and beyond.
6. Book your ideal Alerta with a vacation package
Inca, Tambopata, in the Madre de Dios Region of Peru, offers a unique and inexpensive vacation experience. Immerse yourself in the lush Amazon rainforest, where you can explore the vibrant biodiversity, encounter exotic wildlife, and witness breathtaking landscapes. Engage in thrilling activities like jungle treks, riverboat tours, and birdwatching. Experience the local culture by visiting indigenous communities, learning about their traditions, and trying traditional cuisine. For an affordable vacation, there are budget-friendly accommodations and local markets to explore. Inca provides an authentic and unforgettable adventure in the heart of the Peruvian Amazon.
5. Enjoy Sandoval with a travel package
Sandoval in Tambopata, Madre de Dios Region, Peru offers a unique and immersive outdoor vacation experience. Nestled within the Amazon rainforest, this region is a haven for nature lovers. Explore the pristine Sandoval Lake, surrounded by lush greenery and home to diverse wildlife such as macaws, monkeys, and giant river otters. Embark on guided jungle treks to discover the rich biodiversity of the area, including vibrant bird species, towering trees, and exotic plants. Immerse yourself in the local culture by visiting nearby indigenous communities and learning about their traditional way of life. Sandoval promises an unforgettable adventure in the heart of the Peruvian Amazon.
Find the Best Madre de Dios Region Vacation Packages
Madre de Dios Region Essential Information
Language | Spanish |
|---|---|
Currency | Peruvian sols |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Padre Aldamiz Intl. Airport (PEM) |
Top Sights | Tambopata National Reserve, Sandoval Lake and Manu National Park |
Madre de Dios Region Hotel Deals

Libelula Hotel
Great stay, friendly owners and staff.
Reviewed on Jun 22, 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Half an hour a at from Puerto Maldonado by boat , the place is lovely, with river view and a feel of the jungle without venturing too far. We felt like we got a good insight into the area, with included excursions on the river and into the jungle. Our guide Yuri, who was with us throughout, was very ...
Reviewed on Sep 23, 2025

Inkaterra Reserva Amazonica
World class!
Reviewed on Oct 19, 2025
Frequently asked questions
Discover the most popular places to visit in Madre de Dios Region
Puerto Maldonado Plaza de Armas
You can find out about the history of Puerto Maldonado with a stop at Puerto Maldonado Plaza de Armas. Wander the riverfront and forest while you're in the area.
Puerto Maldonado Obelisk
Find out about the history of Puerto Maldonado when you spend time at Puerto Maldonado Obelisk. Wander the riverfront and forest while you're in the area.
Manu National Park
Explore the great outdoors at Manu National Park, a lovely green space in Manu.
What to do in Madre de Dios Region

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla

Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing
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