Mesopotamia Vacations from $247

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • Better together

    Save up to $1,045 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Your Mesopotamia Vacation

Excellent adventures await when you reserve a Mesopotamia vacation package. Whether you're a foodie, history buff or just a traveler who appreciates new places, there's something for everyone in this vibrant city. Fill your trip to Mesopotamia with tours of some of its leading attractions. First stop? Make a beeline for Windsor Mills Covered Bridge. Expedia can help you escape your routine. Tailor your vacation to Mesopotamia to match your travel style, whatever that may be!

The Latest Mesopotamia vacation packages

Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites Cleveland/Independence

Hampton Inn & Suites Cleveland/Independence

2.5 out of 5
Save 100% on your flight
Price was $357, price is now $247 per person
$247
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Cleveland (CLE)
8.8/10 Excellent! (1,010 reviews)
There was women underwear left in the bathroom drawer

Reviewed on Oct 27, 2025

Hotel Indigo Cleveland Downtown by IHG

Hotel Indigo Cleveland Downtown by IHG

3.5 out of 5
Downtown Cleveland
Save 100% on your flight
Price was $449, price is now $306 per person
$306
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Cleveland (CLE)
8.4/10 Very Good! (1,409 reviews)
Perfect location for everything downtown. Clean room and friendly staff

Reviewed on Oct 25, 2025

Kimpton Schofield Hotel by IHG

Kimpton Schofield Hotel by IHG

4.5 out of 5
Downtown Cleveland
Save 100% on your flight
Price was $414, price is now $285 per person
$285
per person
Dec 12 - Dec 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Cleveland (CLE)
8.6/10 Excellent! (1,014 reviews)
Room was very clean. I did not like the policy of pre-charging $200 for 2 nights for incidentals and having to wait for my refund.

Reviewed on Oct 26, 2025

Holiday Inn Cleveland Clinic by IHG

Holiday Inn Cleveland Clinic by IHG

3 out of 5
Fairfax
Price was $611, price is now $454 per person
$454
per person
Jan 13 - Jan 17
found 1 day ago
Roundtrip flight included
New York (NYC) to Cleveland (CLE)
8.8/10 Excellent! (1,223 reviews)
The room carpet had dirty spots. The room had dust in the corners, food crumbs on the carpeted flooring; clearly it had not been vacuumed thoroughly if at all.

Reviewed on Oct 30, 2025

InterContinental Cleveland by IHG

InterContinental Cleveland by IHG

4.5 out of 5
Fairfax
Price was $755, price is now $562 per person
$562
per person
Jan 13 - Jan 17
found 1 day ago
Roundtrip flight included
New York (NYC) to Cleveland (CLE)
9/10 Wonderful! (833 reviews)
Staff and amenities were great. The skywalk to the Cleveland Clinic made it easy to get where I needed to go.

Reviewed on Oct 29, 2025

Don't see what you're looking for?
See all available trips from Columbus to Mesopotamia
View all trips

Mesopotamia Hotel Deals

Best Western Park Hotel

Best Western Park Hotel

2.5 out of 5
136 N Park Ave, Warren, OH
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Nov 16 to Nov 17
$105 total
Nov 16 - Nov 17
Total with taxes and fees
8.4/10 Very Good! (962 reviews)
Quick walk to Park, restaurants and Robins Theater.

Reviewed on Oct 27, 2025

Best Western Park Hotel
Holiday Inn Express Newton Falls by IHG

Holiday Inn Express Newton Falls by IHG

2.5 out of 5
4185 State Route 5, Newton Falls, OH
Fully refundable
$92 nightly
The price is $106 total per night from Nov 9 to Nov 10
$106 total
Nov 9 - Nov 10
Total with taxes and fees
8.6/10 Excellent! (667 reviews)
Good enough.

Reviewed on Oct 17, 2025

Holiday Inn Express Newton Falls by IHG
Falls Inn

Falls Inn

2.5 out of 5
4248 State Rte 5, Newton Falls, OH
$67 nightly
The price is $77 total per night from Oct 31 to Nov 1
$77 total
Oct 31 - Nov 1
Total with taxes and fees
7.6/10 Good! (162 reviews)
This is a great little motel. Rooms are clean and updated. You are able to park directly in front of your room.

Reviewed on Aug 31, 2025

Falls Inn
See all 110 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mesopotamia Vacation Packages

Mesopotamia Essential Information

Language
English
Currency
U.S dollars
Top Sights
Nelson-Kennedy Ledges State Park, Pioneer Waterland & Dry Fun Park and Century Village Museum

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Mesopotamia vacation package cost?
You can grab a vacation package to this top destination from $247 on Expedia. But how much your vacation to Mesopotamia costs will depend on the length of stay, season and hotel choice.
What are the cheapest months to go to Mesopotamia?
You can usually find lower prices and greater availability in November, December and January. Check out our cheap Mesopotamia vacation packages and you could land some excellent off-season deals.
How many days is enough for Mesopotamia?
The ideal length of your Mesopotamia vacation depends on what you'd like to do. Typically, a few days to a week will give you plenty of time to go to all the major attractions and discover some hidden gems along the way.
How to find the best Mesopotamia package deals?
Use Expedia's filter tool to help you find some of the best Mesopotamia package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Mesopotamia package deals in the off-peak season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a Mesopotamia vacation as a package?
You can enjoy significant savings on your next Mesopotamia retreat by booking a tailored vacation package. Click on the "Package" heading, then enter your destination and travel dates to see some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Mesopotamia?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Mesopotamia break.
Does Expedia offer Book Now, Pay Later Mesopotamia vacation packages?
Your Mesopotamia break is meant to be an escape from your daily routine, not a reason for money-related stress. So to allow you a little more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.