Mesopotamia Vacations from $295

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mesopotamia Vacation

Excellent adventures await when you reserve a Mesopotamia vacation package. Whether you're a foodie, history buff or just a traveler who appreciates new places, there's something for everyone in this vibrant city. Fill your trip to Mesopotamia with tours of some of its leading attractions. First stop? Make a beeline for Windsor Mills Covered Bridge. Expedia can help you escape your routine. Tailor your vacation to Mesopotamia to match your travel style, whatever that may be!

The Latest Mesopotamia vacation packages

Price found within the past 48 hours. Click for updated prices.
Highlander Inn Cleveland Beachwood Near I-480

Highlander Inn Cleveland Beachwood Near I-480

2.5 out of 5
Save 100% on your flight
Price was $393, price is now $295 per person
$295
per person
Sep 25 - Sep 30
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cleveland (CLE)
4.6/10 (11 reviews)

Comfort Suites Hartville - North Canton

Comfort Suites Hartville - North Canton

2.5 out of 5
Save 100% on your flight
Price was $834, price is now $579 per person
$579
per person
Oct 8 - Oct 15
found 1 day ago
Roundtrip flight included
New York (NYC) to Cleveland (CLE)
9.6/10 Exceptional! (1,000 reviews)
Great location. Room clean and friendly staff

Reviewed on Aug 4, 2026

Fidelity Hotel

Fidelity Hotel

4.5 out of 5
Downtown Cleveland
Save 100% on your flight
Price was $435, price is now $323 per person
$323
per person
Oct 10 - Oct 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cleveland (CLE)
9.6/10 Exceptional! (858 reviews)
Bed is 100% cleaning, just ok, other things are good

Reviewed on Aug 5, 2026

Cedar Stables Inn and Suites

Cedar Stables Inn and Suites

2.5 out of 5
Save 100% on your flight
Price was $401, price is now $298 per person
$298
per person
Sep 18 - Sep 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cleveland (CLE)
8.8/10 Excellent! (547 reviews)

InterContinental Suites Hotel Cleveland by IHG

InterContinental Suites Hotel Cleveland by IHG

4 out of 5
Fairfax
Save 100% on your flight
Price was $564, price is now $428 per person
$428
per person
Sep 4 - Sep 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cleveland (CLE)
8.8/10 Excellent! (1,005 reviews)
The people at the front desk was super helpful with public transport information, the housekeeping was nice, and even the security in the lobby was friendly. First time in Cleveland and I loved the experience!

Reviewed on Aug 5, 2026

Don't see what you're looking for?
See all available trips from Columbus to Mesopotamia
View all trips

Mesopotamia Hotel Deals

Holiday Inn Express Newton Falls by IHG

Holiday Inn Express Newton Falls by IHG

2.5 out of 5
4185 State Route 5 Newton Falls OH
Fully refundable
$97 nightly
The price is $111 total per night from Aug 16 to Aug 17
$111 total
Aug 16 - Aug 17
Total with taxes and fees
8.6/10 Excellent! (733 reviews)
"Room wasn’t very clean. No bath mat no Kleenex dusty. AC was fine as was fridge."

Reviewed on Aug 4, 2026

Holiday Inn Express Newton Falls by IHG
Best Western Park Hotel

Best Western Park Hotel

2.5 out of 5
136 N Park Ave Warren OH
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Aug 31 to Sep 1
$107 total
Aug 31 - Sep 1
Total with taxes and fees
Best Western Park Hotel
Falls Inn

Falls Inn

2.5 out of 5
4248 State Rte 5 Newton Falls OH
$68 nightly
The price is $78 total per night from Aug 19 to Aug 20
$78 total
Aug 19 - Aug 20
Total with taxes and fees
7.6/10 Good! (195 reviews)
"Room was fairly clean, beds were somewhat comfortable, pillows could use replaced. There was no breakfast, no pool. It was pretty bland and basic for the price, but we needed somewhere to stay at the last minute."

Reviewed on Aug 3, 2026

Falls Inn
See all 118 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mesopotamia Vacation Packages

Mesopotamia Essential Information

Language
English
Currency
U.S dollars
Top Sights
Nelson-Kennedy Ledges State Park, Pioneer Waterland & Dry Fun Park and Century Village Museum

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Mesopotamia vacation package cost?
You can grab a vacation package to this top destination from $295 on Expedia. But how much your vacation to Mesopotamia costs will depend on the length of stay, season and hotel choice.
What are the cheapest months to go to Mesopotamia?
You can usually find lower prices and greater availability in November, December and January. Check out our cheap Mesopotamia vacation packages and you could land some excellent off-season deals.
How many days is enough for Mesopotamia?
The ideal length of your Mesopotamia vacation depends on what you'd like to do. Typically, a few days to a week will give you plenty of time to go to all the major attractions and discover some hidden gems along the way.
How to find the best Mesopotamia package deals?
Use Expedia's filter tool to help you find some of the best Mesopotamia package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Mesopotamia package deals in the off-peak season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a Mesopotamia vacation as a package?
You can enjoy significant savings on your next Mesopotamia retreat by booking a tailored vacation package. Click on the "Package" heading, then enter your destination and travel dates to see some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Mesopotamia?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Mesopotamia break.
Does Expedia offer Book Now, Pay Later Mesopotamia vacation packages?
Your Mesopotamia break is meant to be an escape from your daily routine, not a reason for money-related stress. So to allow you a little more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.