Title: Midsize Car Rentals in Casco Viejo - Expedia.com ![](https://images.trvl-media.com/place/6285189/5de33a79-734e-444d-a7f7-18272ceb73c2.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Rental Companies in Casco Viejo - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. 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[Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6285189) ## Frequently asked questions ### How can I get a cheap midsize car rental in Casco Viejo with Expedia? ### How much does it cost to rent a midsize car in Casco Viejo? ### How old do you have to be to rent a midsize car in Casco Viejo? ### Why should I rent a midsize car in Casco Viejo? ### How can I rent a midsize car in Casco Viejo? ### Why should I rent a midsize car through Expedia? ### What happens if I need to cancel my Casco Viejo midsize car rental reservation? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near San Felipe ](https://www.expedia.com/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels) - [Hotels near Iglesia de la Merced ](https://www.expedia.com/Iglesia-De-La-Merced-Hotels.0-l553248621562725896-0.Travel-Guide-Filter-Hotels) - [Hotels near Metropolitan Cathedral of Panama ](https://www.expedia.com/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels) - 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[Palacio de las Garzas ](https://www.expedia.com/Palacio-De-Las-Garzas-Casco-Viejo.d6078483.Vacation-Attraction) - [Amador Theater ](https://www.expedia.com/Amador-Theater-Casco-Viejo.d553248621562725887.Vacation-Attraction) - [Bolivar Square ](https://www.expedia.com/Bolivar-Square-Casco-Viejo.d553248621532965265.Vacation-Attraction) - [Palacio Bolivar ](https://www.expedia.com/Palacio-Bolivar-Casco-Viejo.d553248621562725897.Vacation-Attraction) - [National Theater ](https://www.expedia.com/National-Theater-Casco-Viejo.d6078479.Vacation-Attraction) - [Club de Clases y Tropas ](https://www.expedia.com/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [Visit Barrio Chino ](https://www.expedia.com/Panama-City-Barrio-Chino.dx714749931894550528) - [Anita Villalaz Theater ](https://www.expedia.com/Anita-Villalaz-Theater-Casco-Viejo.d553248621532964221.Vacation-Attraction) - [Paseo de Las Bovedas ](https://www.expedia.com/Paseo-De-Las-Bovedas-Casco-Viejo.d553248621562725898.Vacation-Attraction) - 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[Panamá Province Vacation Rentals ](https://www.expedia.com/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations) - [Things to do in Panamá Province ](https://www.expedia.com/Things-To-Do-In-Panama-Province.d6246281.Travel-Guide-Activities)