Santa Ana
Panama City
Visit Santa Ana
Stay near popular Santa Ana attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
$48
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
$99
per adult
94% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
$145
per adult
98% of travellers recommend
Panama: Monkey and Sloth Jungle Habitat Panama Tour
$60
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
$32
per adult
100% of travellers recommend
Panama City: Poin Full Package Experience
$155
per adult
98% of travellers recommend
Santa Ana Hotel Deals
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
$31 nightly
The price is $35 total per night from Oct 18 to Oct 19
$35 total
Oct 18 - Oct 19
Total with taxes and fees
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
8/10 Very Good! (19 reviews)
"Good location but basic otherwise. Staff not overly helpful on the whole."
Reviewed on Sep 27, 2026
Casco View Life Residences
C. 16 Oeste Panama City Provincia de Panamá
$106 nightly
The price is $117 total per night from Oct 16 to Oct 17
$117 total
Oct 16 - Oct 17
Total with taxes and fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
$132 nightly
The price is $145 total per night from Oct 21 to Oct 22
$145 total
Oct 21 - Oct 22
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
$102 nightly
The price is $112 total per night from Nov 9 to Nov 10
$112 total
Nov 9 - Nov 10
Total with taxes and fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,001 reviews)
"We just didn’t have a microwave. Staff was amazing, breakfast variety was good everyday. Will be back!"
Reviewed on Oct 9, 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
$145 nightly
The price is $160 total per night from Nov 9 to Nov 10
$160 total
Nov 9 - Nov 10
Total with taxes and fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
$133 nightly
The price is $133 total per night from Oct 24 to Oct 25
$133 total
Oct 24 - Oct 25
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (1,778 reviews)
"Hgghhggghhvhchughugg. Hughhggg"
Reviewed on Oct 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Santa Ana
Learn more about Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
Santa Ana
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