Santa Ana
Panama City
Visit Santa Ana
Stay near popular Santa Ana attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
$48
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
$99
per adult
94% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
$145
per adult
98% of travellers recommend
All-inclusive catamaran 7.5h Isla Taboga from Panama City
$99
per adult
94% of travellers recommend
Panama: Monkey and Sloth Jungle Habitat Panama Tour
$60
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
$32
per adult
100% of travellers recommend
Santa Ana Hotel Deals
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
$44 nightly
The price is $49 total per night from Nov 3 to Nov 4
$49 total
Nov 3 - Nov 4
Total with taxes and fees
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
8/10 Very Good! (21 reviews)
"Room was clean and very basic. No frills! The bed and pillows were comfortable and the AC worked well. Good location."
Reviewed on Oct 19, 2026
Casco View Life Residences
C. 16 Oeste Panama City Provincia de Panamá
$111 nightly
The price is $122 total per night from Oct 25 to Oct 26
$122 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
$124 nightly
The price is $137 total per night from Oct 25 to Oct 26
$137 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (6,108 reviews)
"My experience was wonderful. The staff was pleasant, breakfast had a lot of options. I have already recommended people to stay at rui plaza"
Reviewed on Oct 20, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
$99 nightly
The price is $109 total per night from Nov 9 to Nov 10
$109 total
Nov 9 - Nov 10
Total with taxes and fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
$128 nightly
The price is $141 total per night from Nov 19 to Nov 20
$141 total
Nov 19 - Nov 20
Total with taxes and fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,778 reviews)
"It was clean and the bed was comfortable. The restaurant for both supper and breakfast was very overpriced for food that was very average. Two of my family members had breakfast included in the price of the room but they had to take the 6am shuttle and that’s what time breakfast starts. It would ..."
Reviewed on Oct 20, 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
$132 nightly
The price is $145 total per night from Nov 3 to Nov 4
$145 total
Nov 3 - Nov 4
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Santa Ana
Learn more about Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
Santa Ana
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