Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.
Things to do
Panama City: Poin Full Package Experience
Panama City: POIN Swing Experience
From Panama City: San Blas Island Hopping Day Tour
Boat tour in the Panama Canal to Monkeys and sloths islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Santa Ana Hotel Deals
Casco View Apartments
The building is great, the apartment was perfect, the staff superbe, and they take care of the building, guests and security. There is a supermarket across the street which makes your life so much easier. The issue, as others have mentioned, is that the building is at the limit of the safe area in ...
Reviewed on Apr 29, 2026
Hotel Riu Plaza Panama
It's always amazing! That's why we keep coming back!
Reviewed on May 1, 2026
Crowne Plaza Panama Airport by IHG
Personal Muy Atento y Excelente Limpieza de Habitaciones.
Reviewed on May 1, 2026
The Executive Hotel
great location, very friendly staff, efficient elevators. Nice room space. But breakfast was average. Selection of food average. Could be improved alot.
Reviewed on May 1, 2026
Dreams Playa Bonita Panama - All Inclusive
Clean room. Very friendly staff.
Reviewed on Apr 29, 2026
Principe Hotel and Suites
I didn’t realize that a standard room does not have a fridge, should have read better but overall good for the price and location was close to everything
Reviewed on May 2, 2026
Other neighborhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Maracana Stadium.
Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.
Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Bridge of the Americas, a few notable attractions nearby.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
Santa Ana
Explore a world of travel with Expedia
- Hotels near Barrio Chino
- Hotels near Avenida Central
- Hotels near Amador Theater
- Hotels near Danilo Perez Foundation
- Hotels near Iglesia de la Merced
- Hotels near Casco Viejo
- Luxury Hotels in Casco Viejo
- 5 Star Hotels in Casco Viejo
- Cheap Hotels in Casco Viejo
- Hotels near San Felipe
- Hotels with Restaurants in Casco Viejo
- Hotel Wedding Venues Hotels in Casco Viejo
- Hotels with a Gym in Casco Viejo
- Hotels with a Pool in Casco Viejo
- Boutique Hotels in Casco Viejo
- Casino Hotels in Casco Viejo
- Hotels with Free Parking in Casco Viejo
- Family Hotels in Casco Viejo
- Business Hotels in Casco Viejo
- Resorts & Hotels with Spas in Casco Viejo
- Oceanfront Hotels in Casco Viejo
- Historic Hotels in Casco Viejo
- Beach Hotels in Casco Viejo
- Gay friendly Hotels in Casco Viejo
- 4 Star Hotels in Casco Viejo
- Hotels with smoking rooms in Casco Viejo
- Hotels with Laundry Facilities in Casco Viejo
- Hotels with Free Breakfast in Casco Viejo
- Marriott Hotels & Resorts in Casco Viejo
- Hotels with Bars in Casco Viejo
- Pet-Friendly Hotels in Casco Viejo
- 3 Star Hotels in Casco Viejo
- Romantic Hotels in Casco Viejo
- Quiet Resorts & in Casco Viejo
- Hilton Hotels in Casco Viejo
- Ace Hotel in Casco Viejo
- Hotels with Balconies in Casco Viejo
- Winery Hotels in Casco Viejo
- Hotels with Suites in Casco Viejo
- Extended Stay Hotels in Casco Viejo
- Hotels with Air Conditioning in Casco Viejo
- Hotels with Childcare in Casco Viejo
- Hotels with Connecting Rooms in Casco Viejo
- Hotels with a View in Casco Viejo
- Hotels with an Outdoor Pool in Casco Viejo
- Hotels near Palacio de las Garzas
- Hotels near Metropolitan Cathedral of Panama
- Hotels near Independence Square
- Hotels near Museum of History Panama
- Hotels near Ancon Hill
- Hotels near El Chorrillo
- Hotels near Bolivar Square
- Hotels near Palacio Bolivar
- Hotels near National Theater
- Hotels near Club de Clases y Tropas
- Hotels near Paseo de Las Bovedas
- Hotels near National Institute of Culture
- Hotels near Plaza de Francia
- Hostels in Estación Lotería
- Hotels near Estación Lotería
- Apartments in Estación Lotería
- Vacation Homes in Estación Lotería
- Condo Rentals in Estación Lotería
- Hotels near Curundu
- Visit Barrio Chino
- Avenida Central
- Amador Theater
- Museum of Contemporary Art Panama
- Visit Casco Viejo
- Mi Pueblito
- Iglesia de la Merced
- Casco Viejo Vacations
- Palacio de las Garzas
- Afro Antillean Museum
- Visit El Chorrillo
- Metropolitan Cathedral of Panama
- Independence Square
- Museum of History Panama
- Interoceanic Canal Museum
- Flag of Cerro Ancón
- Ancon Hill
- Bolivar Square
- Palacio Bolivar
- National Theater
- Club de Clases y Tropas
- Anita Villalaz Theater
- Paseo de Las Bovedas
- National Institute of Culture
- Museum of Natural Science
- Maracana Stadium
- Visit Curundu
- Car rentals near Casco Viejo
- Thrifty Car Rental Rental Cars in Casco Viejo
- Hertz Rental Cars in Casco Viejo
- First Car Rental Rental Cars in Casco Viejo
- Van Car Rentals in Casco Viejo
- Alamo Rent A Car Rental Cars in Casco Viejo
- Midsize Car Rentals in Casco Viejo
- Suv Car Rentals in Casco Viejo
- Europcar Rental Cars in Casco Viejo
