Museum District Vacations from $199
Book a Hotel + Flight or Car together to unlock savings
Photo by Hazem Abdul
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Houston Museum District Vacation
Houston Museum District is beckoning! Whatever type of break you have in mind, you can see and experience more of this neighborhood with a Houston Museum District vacation package. Start your trip to Houston Museum District by visiting nearby attractions such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Don't just dream it — turn it into a reality! Reserve your perfect Houston Museum District vacation with Expedia and get to where you're going your way.
The Latest Museum District Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Kompose Residences Houston Cy-Fair
Save 100% on your flight
Price was $357, price is now $199 per person
$199
per person
Feb 18 - Feb 22
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
10/10 Exceptional! (2 reviews)
Hi! My friends and i stayed here for 2 nights and we absolutely loved it! The staff was so kind and polite and even gave us an extra hour for check out time since we got in late! I will definitely be recommending this hotel to everyone! Thank you so much!
Reviewed on Dec 15, 2025
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Save 100% on your flight
Price was $454, price is now $263 per person
$263
per person
Feb 18 - Feb 22
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,889 reviews)
Room was excellent. Staff was great. Only problem was expedia led me to believe I was booking a room with a balcony but when I got to the property I got a room without one. Double check what you’re booking and then check again.
Reviewed on Dec 15, 2025
Reside Houston Dwntwn, Wyndham
Downtown Houston
Save 100% on your flight
Price was $1,076, price is now $632 per person
$632
per person
Mar 9 - Mar 14
found 22 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.6/10 Excellent! (832 reviews)
Clean rooms, very nice front desk staff.
Reviewed on Dec 12, 2025
Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center
Save 100% on your flight
Price was $492, price is now $293 per person
$293
per person
Feb 18 - Feb 22
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (3,554 reviews)
Great hotel I would definitely stay again
Reviewed on Dec 14, 2025
Where to stay in Museum District
Find the best Museum District areas and neighborhoods for the activities you enjoy most. Learn more about Museum District
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Museum District Hotel Deals
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $149 total per night from Dec 22 to Dec 23
$149 total
Dec 22 - Dec 23
Total with taxes and fees
8.2/10 Very Good! (3,067 reviews)
We did not have breakfast at the hotel. The staff was very busy but very pleasant. They even upgraded us, which was very nice..
Reviewed on Dec 12, 2025
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $326 total per night from Dec 24 to Dec 25
$326 total
Dec 24 - Dec 25
Total with taxes and fees
8.8/10 Excellent! (1,839 reviews)
Great service
Reviewed on Dec 4, 2025
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $90 total per night from Dec 20 to Dec 21
$90 total
Dec 20 - Dec 21
Total with taxes and fees
8.4/10 Very Good! (3,944 reviews)
Cute room, great staff at the restaurant, enjoyed a couple of the amenities.
Reviewed on Dec 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Museum District
Houston Natural Science Museum
4.5/5(805 reviews)
You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's lively festivals and entertainment choices.
Children's Museum of Houston
4.5/5(385 reviews)
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's fascinating museums and entertainment choices.
Buffalo Soldiers National Museum
You can spend time browsing the exhibits at Buffalo Soldiers National Museum during your trip to Houston. Experience the fascinating museums and great live music in this vibrant area.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
- Hotels near Downtown Houston
- Cheap Hotels in Houston
- Hotels near MD Anderson Cancer Center
- Hotels near Health Museum
- Hotels near Children's Museum of Houston
- Hotels near Houston Natural Science Museum
- Hotels near Miller Outdoor Theater
- B&B in Museum District Station
- Hotels near Museum District Station
- Hotels near Holocaust Museum Houston
- Hotels near Clayton Library Center for Genealogical Research
- Hotels near Houston Zoo
- Hotels near Houston Museum of Fine Arts
- Hotels near Asia Society Texas Center
- Hotels near Hermann Park
- Hotels near Buffalo Soldiers National Museum
- Hotels near Rice University
- Hotels near Czech Center Museum
- Hotels near Lawndale Art Center
- Hotels near Texas Medical Center
- Apartments in Memorial Hermann Hospital/Houston Zoo Station
- Vacation Homes in Memorial Hermann Hospital/Houston Zoo Station
- Hotels near Memorial Hermann Hospital/Houston Zoo Station
- Resorts in Memorial Hermann Hospital/Houston Zoo Station
- Condo Rentals in Memorial Hermann Hospital/Houston Zoo Station
- Hotels near NRG Stadium
- Apartments in Dryden/TMC Station
- Hotels near Dryden/TMC Station
- Aparthotels in Dryden/TMC Station
- Hotels near South Central Houston
- Gay friendly Hotels in South Central Houston
- Hotels near Riverside Terrace
- Hotels near The Chapel of St. Basil
- Hotels near Continental Club
- Hotels near University of St. Thomas
- Hotels near Reckling Park
- Hotels near Rothko Chapel
- Hotels near Cy Twombly Gallery
- Hotels near James Turrell's Twilight Epiphany Skyscape
- Hotels near Ensemble Theatre
- Hotels near Menil Collection
- Cheap Hotels in Texas Medical Center
- Hyatt Hotels in Texas Medical Center
- Pet-friendly Hotels in Texas Medical Center
- Hotels near Diverse Works
- Hotels with Kitchenettes in Texas Medical Center
- Hotels near Midtown Arts and Theater Center Houston
- Hotels near Rice Stadium
- La Quinta Inn & Suites Hotels in Texas Medical Center
- Luxury Hotels in Texas Medical Center
- 4 Star Hotels in Texas Medical Center
- 5 Star Hotels in Texas Medical Center
- Houston Zoo
- Houston Vacations
- Houston Natural Science Museum
- Children's Museum of Houston
- Houston Museum of Fine Arts
- Hermann Park
- Miller Outdoor Theater
- Holocaust Museum Houston
- Buffalo Soldiers National Museum
- Cullen Sculpture Garden
- Rice University
- MD Anderson Cancer Center
- Byzantine Chapel Fresco Museum
- Menil Collection
- The Chapel of St. Basil
- Reckling Park
- University of St. Thomas
- Cy Twombly Gallery
- James Turrell's Twilight Epiphany Skyscape
- Ensemble Theatre
- Rice Stadium
- Bering Memorial Methodist Church
- Texas Southern University
- Visit Riverside Terrace
- Midtown Vacations
- Visit Texas Medical Center
- Car rentals near Houston
- Car rentals near Children's Museum of Houston
- Car rentals near Houston Museum of Fine Arts
- Car rentals near Hermann Park
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near South Central Houston
- Car rentals near University of St. Thomas
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Thrifty Car Rental Rental Cars in Texas Medical Center
- Car rentals near Texas Medical Center
- Enterprise Rental Cars in Texas Medical Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.