South Central Houston Vacations from $268
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Your South Central Houston Vacation
Leave the stress of travel planning behind with a South Central Houston vacation package. With all the details locked in before you go, all you have to do is enjoy this university neighborhood's nightlife, history and dining. Some nearby attractions to visit during your trip to South Central Houston include Toyota Center, Minute Maid Park and Houston Zoo. Stop dreaming and start doing. When you're ready to book your next vacation to South Central Houston, Expedia will help get you there.
The Latest South Central Houston Vacation Packages
Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Houston East at Normandy
Northeast Houston
Save 100% on your flight
per person
Oct 9 - Oct 15
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8/10 Very Good! (634 reviews)
All staff very friendly except for the Night Shift front office guy who was not friendly at all i would ask questions and he get bother because he was always in the phone
Reviewed on Jul 19, 2025
Moody Gardens Hotel, Spa and Convention Center
Near West End
Save 100% on your flight
per person
Sep 5 - Sep 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,811 reviews)
We enjoyed our stay! Pool was a little chilly but it didn’t stop us. Beautiful location.
Reviewed on Jul 29, 2025
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
South Central Houston Hotel Deals
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from Aug 3 to Aug 4
$116 total
Aug 3 - Aug 4
Total includes taxes and fees
8.2/10 Very Good! (1,487 reviews)
"Nice place to stay for work and pleasant"
Reviewed on Jul 29, 2025
Hotel Zaza Houston Museum District
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
$223 nightly
The price is $261 total per night from Aug 14 to Aug 15
$261 total
Aug 14 - Aug 15
Total includes taxes and fees
8.8/10 Excellent! (1,729 reviews)
"The welcome snack and wine were nice! Dinner was delicious."
Reviewed on Jul 30, 2025
InterContinental Houston by IHG
6750 Main St, Houston, TX
Fully refundable
$167 nightly
The price is $192 total per night from Aug 24 to Aug 25
$192 total
Aug 24 - Aug 25
Total includes taxes and fees
9.2/10 Wonderful! (1,017 reviews)
"The property is very well maintained and the staff is very attentive. Great housekeeping staff and front of house staff. Close to public transportation and activities. Great place to stay!"
Reviewed on Jul 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in South Central Houston
Rice University
4.5/5(356 reviews)
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's fascinating museums and acclaimed art scene.
University of Houston
4/5(392 reviews)
Enjoy the collegiate vibe around University of Houston, a top university in Houston. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Houston Zoo
4.5/5(998 reviews)
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.
Things to do
Houston Museum of Natural Science General Admission Ticket
$25
per adult
98% of travellers recommend
Houston: Brunch & Beats - Hip-Hop Party Bike Brunch Tour
$65
per adult
100% of travellers recommend
Houston: Lovers & Friends 90s R&B Party Tour
$47
per adult
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- Houston Vacations
- Texas Southern University
- Buffalo Soldiers National Museum
- Houston Zoo
- Children's Museum of Houston
- Hermann Park
- Holocaust Museum Houston
- Houston Museum of Fine Arts
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- Carl Lewis International Track and Field Complex
- Houston Natural Science Museum
- Ensemble Theatre
- University of Houston
- Miller Outdoor Theater
- Cullen Sculpture Garden
- Midtown Vacations
- Visit Houston Museum District
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.