A city skyline with a prominent arch landmark, several high-rise buildings, and boats on a river.

Search Guest Houses in O'Fallon

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15
In one month
Nov 27 - Nov 29
In two months
Dec 25 - Dec 27

Our top choices for O'Fallon guest houses

A modern living room with a brick wall, a sofa, a coffee table, and a TV.

1. Cozy, Fun, and One-Of-A-Kind!

Cozy, Fun, and One-Of-A-Kind!
Shaw
9.2 out of 10, Wonderful, (149 reviews)
"Great place to stay super cozy"
United States
Riley C.
$128 nightly
The price is $138
Oct 29 - Oct 30
Total with taxes and fees
Cozy, Fun, and One-Of-A-Kind!
A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

2. Grand Center Inn

Grand Center Inn
3.0 star property
Grand Center
9.4 out of 10, Exceptional, (105 reviews)
"Lovely room, easy check in, close to Fox, comfy bed"
United States
Leon and Janis
$154 nightly
The price is $182
Oct 28 - Oct 29
Total with taxes and fees
Grand Center Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top O'Fallon Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"This is by far my favorite hotel to stay in when im in town."
Scott 2-night trip
Posted 5 hours ago
Drury Plaza Hotel St. Louis Union Station

Find out more about O'Fallon

O'Fallon Guest Houses information

Number of reviews
254
Accommodation
4 Guest Houses
Lowest Price
$138
Highest Price
$182

Explore a world of travel with Expedia