San Diego Vacations from $537
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Your San Diego Vacation
From its highlights to its hidden delights, this city is best experienced with a San Diego vacation package. Book a hotel in La Candelaria, which is great for dining, history and shopping. Want to explore your surroundings? Atanasio Giradot Stadium, Botero Plaza and Lights Park are among the top places to visit during your trip to San Diego. Expedia will help you escape your routine. Tailor your vacation to San Diego to suit your travel style, whatever that may look like.
The Latest San Diego Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Charlee Hotel
El Poblado
Price was $834, price is now $537 per person
$537
per person
Mar 24 - Mar 27
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
8.8/10 Excellent! (1,002 reviews)
spent extra money on a hot tub suite that didn't work
Reviewed on Jan 11, 2026
MYLOS Hotel Boutique
Save 100% on your flight
Price was $1,090, price is now $680 per person
$680
per person
Feb 27 - Mar 3
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Medellín (MDE)
7.2/10 Good! (5 reviews)
Mylos hotel was a hidden gem in Guatape. Such a cute luxury boutique hotel and near everything. From the moment we stepped in we were greeted by the wonderful staff. Hotel look just like the pictures. Will definitely stay here again in the future.
Reviewed on Nov 20, 2025
Where to stay in San Diego
Find the best San Diego areas and neighborhoods for the activities you enjoy most. Learn more about San Diego
El Poblado
6 out of top 10 points of interest in this area
4.5/5(1,487 area reviews)
Golden Blocks brimming with commercial activity, El Poblado offers vibrant nightlife at Lleras Park, cultural attractions like El Castillo Museum, and ample shopping options with multiple malls. Accessible via Medellín Metro and bus lines.
San Diego Hotel Deals
La Quinta by Wyndham Medellin
Carrera 38 # 26-13, Avenida las Palmas Medellín Antioquia
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $76 total per night from Jan 15 to Jan 16
$76 total
Jan 15 - Jan 16
8.8/10 Excellent! (1,004 reviews)
We wanted more restaurant options for lunch or dinner
Reviewed on Dec 31, 2025
Metropolitan Living by HOUSY
Carrera 43A # 32 - 128 Medellin Antioquia
$75 nightly
The price is $75 total per night from Jan 14 to Jan 15
$75 total
Jan 14 - Jan 15
9.4/10 Exceptional! (30 reviews)
Good room, only issue was wifi a bit slow. Hotel is close to supermarket, restaurants, shopping and nightlife.
Reviewed on Dec 27, 2025
Calle Flora Hotel by Jalo
# 37-40 Calle 9A Medellín
$84 nightly
The price is $84 total per night from Jan 14 to Jan 15
$84 total
Jan 14 - Jan 15
9/10 Wonderful! (365 reviews)
This is a new hotel. The room was clean. The beds were comfortable. Great location. My only complaint is that the wifi barely worked to the point that I would say if you need it then you should stay elsewhere.
Reviewed on Jan 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in San Diego
Santafé Mall
During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Check out the lively bars or top-notch restaurants in this walkable area.
Botero Plaza
Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants.
Pueblito Paisa
Take a trip back in time to a replica of a typical old town from the region with a stunning view of the new city.
Things to do
Pablo Escobar Tour : Museum, History and Beer
$40
per adult
94% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
$27
per adult
98% of travellers recommend
Explore a world of travel with Expedia
- Hotels near Medellin General Hospital
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- Hotels near Exposiciones Station
- Hotels near Medellin's Museum of Modern Art
- Hotels near Carlos Vieco Theatre
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- Medellin General Hospital
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- Carlos Vieco Theatre
- Cerro Nutibara
- Medellin Vacations
- Santa Fe Zoological Park
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- Monumento a la Raza
- Medellin Town Hall
- Jose Gutierrez Gomez Medellin Metropolitan Theatre
- Plaza de La Libertad de Medellin
- Medellín Vacations
- Urban Gate
- Parques del Río Medellín
- Visit Antioquia
- La Gorda Sculpture
- Monterrey Comercial Mall
- Cerro El Volador
- Berrio Park
- Coltejer Building
- Botero Plaza
- Medellin Boston's Park
- Poblado Park
- Palacio de la Cultura
- Lokkus Contemporary Art
- Antioquia Museum
- The Dancer's Park
- Lleras Park
- Mercado de San Alejo
- Bolivar's Park
- Car rentals near Buenos Aires
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.