
San Marco Vacations from $801
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Your San Marco Vacation
Avoid the hassle of travel planning with a San Marco vacation package. With all the details locked in before you take off, all you have to do is enjoy this leafy neighborhood's bars and pubs, cafes and culture. Your trip to San Marco wouldn't be complete without stopping by popular attractions nearby such as Orange Park Place Shopping Center, Theatre Jacksonville and Fort Caroline Shopping Center. Stop daydreaming and start doing. When it's time to lock in your ideal vacation to San Marco, Expedia will help get you there.
The Latest San Marco Vacation Packages

Hampton Inn Jacksonville Beach/Oceanfront
Reviewed on Jan 11, 2026



DoubleTree by Hilton Hotel Jacksonville Riverfront
Reviewed on Jan 15, 2026
Where to stay in San Marco

Downtown Jacksonville
Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.
San Marco Hotel Deals

Hilton Garden Inn Jacksonville Downtown Southbank
The room was clean.
Reviewed on Jan 5, 2026

Scottish Inn Jacksonville Downtown
Ac unit was working. Loved the heat and yeah it was a skyway near by made it easy to get around to the places near by
Reviewed on Jan 14, 2026

Homewood Suites by Hilton Jacksonville Downtown-Southbank
Everything was wonderful!
Reviewed on Jan 10, 2026
Discover the most popular places to visit in San Marco

Mayo Clinic Florida
Though Mayo Clinic Florida might be what brings you to town, perhaps you'll have a chance to explore more of Jacksonville while you are here.

Jacksonville Naval Air Station
After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the great live music or attend a sporting event in this family-friendly area.

EverBank Stadium
Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.
Things to do

1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports
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