San Marco Vacations from $337

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Your San Marco Vacation

Avoid the hassle of travel planning with a San Marco vacation package. With all the details locked in before you take off, all you have to do is enjoy this leafy neighborhood's bars and pubs, cafes and culture. Your trip to San Marco wouldn't be complete without stopping by popular attractions nearby such as Orange Park Place Shopping Center, Theatre Jacksonville and Fort Caroline Shopping Center. Stop daydreaming and start doing. When it's time to lock in your ideal vacation to San Marco, Expedia will help get you there.

The Latest San Marco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express Jacksonville South Bartram Prk by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG

2.5 out of 5
Price was $432, price is now $337 per person
$337
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
9.4/10 Exceptional! (1,584 reviews)

Marriott Jacksonville Downtown

Marriott Jacksonville Downtown

4 out of 5
Downtown Jacksonville
Price was $734, price is now $558 per person
$558
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
8.4/10 Very Good! (1,006 reviews)
Very friendly staff. Rooms and lobby have been updated.

Reviewed on Nov 6, 2026

The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
Price was $521, price is now $399 per person
$399
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
8.4/10 Very Good! (1,280 reviews)
We had a wonderful stay at The Omni. They offer so much on the property. I highly recommend staying there. Definitely would go back!

Reviewed on Nov 1, 2026

Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
Price was $522, price is now $411 per person
$411
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
8.4/10 Very Good! (1,547 reviews)
This was a beautiful place to stay. We will be returning again soon.

Reviewed on Nov 6, 2026

Seaside Amelia Inn

Seaside Amelia Inn

3 out of 5
Price was $475, price is now $375 per person
$375
per person
Jan 17 - Jan 20
found 1 day ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
8.6/10 Excellent! (1,163 reviews)
Everything from location, staff and room was exceptional!

Reviewed on Oct 30, 2026

Where to stay in San Marco

Find the best San Marco areas and neighborhoods for the activities you enjoy most. Learn more about San Marco
A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.

Downtown Jacksonville

2 out of top 10 points of interest in this area

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Find hotels in Downtown Jacksonville

San Marco Hotel Deals

Scottish Inn Jacksonville Downtown

Scottish Inn Jacksonville Downtown

2.5 out of 5
2300 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$40 nightly
The price is $45 total per night from Nov 8 to Nov 9
$45 total
Nov 8 - Nov 9
Total with taxes and fees
6.2/10 (1,013 reviews)
"For staffing parking was okay but the air conditioning did not turn off had to unplug it shower did not work in the room smelled like cat urine in the carpet would not recommend it"

Reviewed on Nov 6, 2026

Scottish Inn Jacksonville Downtown
Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank

3 out of 5
1201 Kings Avenue Jacksonville FL
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $148 total per night from Nov 14 to Nov 15
$148 total
Nov 14 - Nov 15
Total with taxes and fees
Homewood Suites by Hilton Jacksonville Downtown-Southbank
Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank

3 out of 5
1201 Kings Avenue Jacksonville FL
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $144 total per night from Dec 3 to Dec 4
$144 total
Dec 3 - Dec 4
Total with taxes and fees
8.4/10 Very Good! (1,002 reviews)
"Very well located & nice customer service."

Reviewed on Nov 7, 2026

Hilton Garden Inn Jacksonville Downtown Southbank
See all 3,073 properties in San Marco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Stay near popular San Marco attractions

Theatre Jacksonville

You can make plans for a show at Theatre Jacksonville during your trip to Jacksonville. Amble around this vibrant area's riverfront or attend a sporting event.
See properties

Things to do

Half-Day City Tour in Downtown Jacksonville

Half-Day City Tour in Downtown Jacksonville

$114
per adult
100% of travellers recommend
Half-Day City Tour in Downtown Jacksonville
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

1 Hour Jet Ski Rental in Jacksonville, FL Jax Jet Skis

$145
per traveler
90% of travellers recommend
1 Hour Jet Ski Rental in Jacksonville, FL Jax Jet Skis
The Escape Game at St. John's Town Center in Jacksonville

The Escape Game at St. John's Town Center in Jacksonville

$42
per adult
100% of travellers recommend
The Escape Game at St. John's Town Center in Jacksonville
See all activities in Jacksonville

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.