Santa Cruz Vacations from $571

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Your Santa Cruz Vacation

Your next big journey is just around the corner with a vacation package to Santa Cruz. Entertainment, food and nothing but great times — you're sure to find it in this neighborhood. Start your trip to Santa Cruz by heading to nearby attractions such as Caparra Ruins, Ruben Rodriguez Coliseum and Puerto Rico National Cemetery. Expedia will help you turn your ideal Santa Cruz vacation into reality, whatever your travel plans or budget.

The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Hacienda Bello Sitio

Mameyes I

Save 100% on your flight

$571

per person

Sep 28 - Oct 5

found 1 day ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

10/10 Exceptional! (4 reviews)

Such a nice and relaxing place to stay. Off the beaten path but not too far from Luquillo

Reviewed on Mar 6, 2026

Isla Verde Beachfront Retreat With Parking

Isla Verde

Save 100% on your flight

$680

per person

Oct 9 - Oct 12

found 2 days ago

Roundtrip non-stop flight included

Boston (BOS) to San Juan (SJU)

10/10 Exceptional! (2 reviews)

Hotel Puerto Valdes

Puerta de Tierra

Save 100% on your flight

$749

per person

Oct 14 - Oct 18

found 2 days ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

8.8/10 Excellent! (710 reviews)

I really enjoyed my stay, and the staff made us feel welcomed.

Reviewed on Aug 7, 2026

VILLA JOYUDA

Save 100% on your flight

$3,627

per person

Sep 27 - Oct 3

found 1 day ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

10/10 Exceptional! (1 review)

It has everything you may need and more

Reviewed on Nov 5, 2025

Signature Collection at Rio Mar

Mameyes II

Save 100% on your flight

$2,967

per person

Oct 19 - Oct 24

found 1 day ago

Roundtrip flight included

Boston (BOS) to San Juan (SJU)

No reviews

Everything is 10 times more expensive compare to any other place I visites

Reviewed on Aug 8, 2026

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz

A beach with a boat, palm trees, and a city skyline in the background.

Isla Verde

1 out of top 10 points of interest in this area

White-sands, beautifully clear water and excellent water sports make this beach one of the most popular in Puerto Rico.

A densely packed urban area with colorful buildings and a clear sky.

Old San Juan

The fascinating museums and captivating waterfront views are top of the list for many visitors to Old San Juan. A stop by Port of San Juan or Castillo de San Cristobal might round out your trip.

A sandy beach with palm trees, a rocky breakwater, and calm ocean waves.

Condado

1 out of top 10 points of interest in this area

Oceanfront and upscale, Condado boasts picturesque beaches alongside hotels, nightclubs, casinos, and shops. Stroll through La Ventana al Mar park, and enjoy easy access to public transport via T21 and D53 bus routes.

The Museo de Arte de Puerto Rico with a red-tiled roof, white columns, and palm trees.

Santurce

3 out of top 10 points of interest in this area

Bask in the sun on Atlantic Ocean beaches and experience vibrant nightlife at La Placita de Santurce, while exploring museums like the Museum of Art of Puerto Rico. Enjoy easy access to public transportation via bus lines and the Tren Urbano.

A beach with palm trees and high-rise buildings in the background.

Ocean Park

Upscale beachfront community with trendy beachgoers, Ocean Park offers kitesurfing and windsurfing opportunities. Stroll along Calle Loíza for bars, restaurants, and boutiques or unwind at nearby Parque Barbosa.

Santa Cruz Hotel Deals

Fairmont El San Juan Hotel

6063 Isla Verde Avenue Carolina

Fully refundableReserve now, pay when you stay

$429 nightly

$476 total

Sep 1 - Sep 2

Total with taxes and fees

8.6/10 Excellent! (2,177 reviews)

"The distribution of the room was odd. The cleaning crew had to be reminded to brig towels and bathroom mat. These issues were corrected, overall a good stay."

Reviewed on Aug 8, 2026

The Condado Plaza Hotel

999 Ashford Avenue San Juan

Fully refundableReserve now, pay when you stay

$198 nightly

$216 total

Sep 1 - Sep 2

Total with taxes and fees

8/10 Very Good! (2,700 reviews)

"Hotel is a little outdated. Only one elevator worked."

Reviewed on Aug 9, 2026

Hyatt Vacation Club at Hacienda del Mar, Dorado

301 Hwy 693 Vega Alta

Fully refundableReserve now, pay when you stay

$172 nightly

$188 total

Sep 1 - Sep 2

Total with taxes and fees

9.4/10 Exceptional! (3,885 reviews)

"This hotel was good"

Reviewed on Aug 9, 2026

See all 3,997 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.