Title: Visit Santa Cruz: 2026 Travel Guide for Santa Cruz, Medellin | Expedia.com [Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d553248635976386952.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d553248635976386952.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d553248635976386952.Travel-Guide-Flights)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d553248635976386952.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d553248635976386952.Destination-Travel-Guides) # Santa Cruz ## Travel Guide ## Visit Santa Cruz Things to do ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_553248635976386952) - Santa Cruz Hotel Deals - Vacation Rentals in Santa Cruz ![Calle Flora Hotel by Jalo](https://images.trvl-media.com/lodging/118000000/117580000/117576800/117576751/f44f7b72_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Calle Flora Hotel by Jalo \# 37-40 Calle 9A Medellín $64 nightly $64 total Feb 22 - Feb 23 Stay at this hotel in Medellín. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Popular attractions Lleras Park and Poblado Park are located ... 9/10 Wonderful! (460 reviews) great Reviewed on Feb 13, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F22%2F2026&endDate=2%2F23%2F2026&selected=117576751&PinnedHotelID=117576751&HadPinnedHotel=true®ionId=553248635976386952) ![Heiss Hotel By Jalo](https://images.trvl-media.com/lodging/106000000/105650000/105647300/105647272/4877276a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Heiss Hotel By Jalo 1460 Cra. 43F Medellín Antioquia $60 nightly $60 total Mar 9 - Mar 10 Stay at this hotel in Medellín. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Popular attractions Poblado Park and Lleras Park are located ... 9/10 Wonderful! (1,183 reviews) All of the above then some, will definitely be staying again Reviewed on Feb 11, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F9%2F2026&endDate=3%2F10%2F2026&selected=105647272&PinnedHotelID=105647272&HadPinnedHotel=true®ionId=553248635976386952) ![Hotel Dorado La 70](https://images.trvl-media.com/lodging/12000000/11580000/11575400/11575368/f4b76736_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Dorado La 70 Carrera 70 No 44 B-66 Medellín $68 nightly $68 total Feb 17 - Feb 18 Book a stay at this business-friendly hotel in Medellín. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 8.8/10 Excellent! (1,839 reviews) Clean, great area Reviewed on Feb 7, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F17%2F2026&endDate=2%2F18%2F2026&selected=11575368&PinnedHotelID=11575368&HadPinnedHotel=true®ionId=553248635976386952) [See all 4,250 properties in Santa Cruz](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026®ionId=553248635976386952) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![York Luxury Suites Medellín](https://images.trvl-media.com/lodging/50000000/49090000/49084200/49084142/5840e468_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### York Luxury Suites Medellín Carrera 43a 17sur 63 Medellín Antioquia Book a stay at this luxury aparthotel in Medellín. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in our reviews. ... 9.4/10 Exceptional! (1,470 reviews) All excelente Reviewed on Feb 12, 2026 [](https://expedia.com/Medellin-Hotels-York-Luxury-Suites-Medellin.h49084142.Hotel-Information) ![Sites Hotel](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500589/5da61242_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sites Hotel Carrera 45 No. 5 - 15 Medellín Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ... 9.2/10 Wonderful! (1,128 reviews) Great staff. I also liked the location, there are a few restaurants on the street but it’s still quiet. Reviewed on Jan 30, 2026 [](https://expedia.com/Medellin-Hotels-Sites-Hotel.h7500589.Hotel-Information) ![Haven](https://images.trvl-media.com/lodging/43000000/42250000/42249800/42249708/86877b56_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Haven Calle 10A #36-29 Medellín Antioquia Stay at this aparthotel in Medellín. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular attractions ... 8.6/10 Excellent! (658 reviews) Outstanding Reviewed on Feb 9, 2026 [](https://expedia.com/Medellin-Hotels-Haven.h42249708.Hotel-Information) [See all properties in Santa Cruz](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635976386952&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Cruz hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2026-02-16&endDate=2026-02-17)[Feb 16 - Feb 17](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2026-02-16&endDate=2026-02-17) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2026-02-17&endDate=2026-02-18)[Feb 17 - Feb 18](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2026-02-17&endDate=2026-02-18) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2%2F20%2F2026&endDate=2%2F22%2F2026)[Feb 20 - Feb 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2%2F20%2F2026&endDate=2%2F22%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976386952&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) ### Popular places to visit ![Foto aérea del Parque de El Poblado, en la ciudad de Medellín, aparece la Iglesia de San José, Católica.](https://images.trvl-media.com/place/6160683/5f402e16-50ab-4b5c-b867-40f6698cda26.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Poblado Park After visiting Poblado Park, make a plan to see the other sights and activities in Medellín. Check out the shops and top-notch restaurants in this walkable area. [](https://expedia.com/Poblado-Park-El-Poblado.d6160683.Vacation-Attraction) ![Such an impressive mall. With the heat that we struggled to adapt to in Medellin, we often found ourselves seeking out the comfort of air conditioned malls. Although, malls are not are favorite thing, this was definitely our favorite mall in Medellin. A must see, if you're in the area. #colombia #shopping #travel](https://images.trvl-media.com/place/6140804/47431e73-3823-4fea-9bdb-59c0219fe9e6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santafé Mall During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Check out the top-notch restaurants or lively bars in this walkable area. [](https://expedia.com/Santafe-Mall-El-Poblado.d6160635.Vacation-Attraction) ![Medellín, Antioquia, Colombia. August 3, 2009: Plaza Mayor Convention Center](https://images.trvl-media.com/place/6165872/90cb41f7-e4d8-461b-950a-26741fdf8e2d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Plaza Mayor Convention Center Learn about the events happening at Plaza Mayor Convention Center during your trip to Medellín. Make time to visit the area's shops, or simply enjoy its lively bars. [](https://expedia.com/Plaza-Mayor-Convention-Center-La-Candelaria.d6165872.Vacation-Attraction) ![Botero Square Sculpture Park featuring a church or cathedral, a square or plaza and a city](https://images.trvl-media.com/place/6100414/19e02f13-b4cb-496a-97bd-2b19a64a936b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Botero Plaza Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants. [](https://expedia.com/Botero-Plaza-La-Candelaria.d6100414.Vacation-Attraction) ![Pueblito Paisa which includes religious elements and a church or cathedral](https://images.trvl-media.com/place/6272340/ddcc22b9-ea0f-4058-b453-2f97aeb38651.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pueblito Paisa Take a trip back in time to a replica of a typical old town from the region with a stunning view of the new city. [](https://expedia.com/Pueblito-Paisa-Medellin.d6272340.Vacation-Attraction) ![Parque Arví! So after you take the first metro-cable up, there is a second more touristy one](https://images.trvl-media.com/place/6292534/b1177ee1-f537-4fdd-947f-bd03e39e6a0b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Arvi Park You can take time to visit Arvi Park during your travels to Medellín. Check out the shops and lively bars in this trendy area. [](https://expedia.com/Arvi-Park-Medellin.d6292534.Vacation-Attraction) ### Things to do ![Pablo Escobar Tour Medellin](https://mediaim.expedia.com/localexpert/3884335/c54bbb59-92e1-4805-ba84-a08920f757a8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pablo Escobar Tour : Museum, History and Beer $32 per adult **94%** of travellers recommend [](https://expedia.com/things-to-do/pablo-escobar-tour-museum.a3884335.activity-details) ![Medellin: Coffee Tour with Hotel Transfers and Meals](https://mediaim.expedia.com/localexpert/48310953/1da14ff4-59ce-4a01-b742-3346f5f6b100.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Medellin: Coffee Tour with Hotel Transfers and Meals $69 per adult **98%** of travellers recommend [](https://expedia.com/things-to-do/medellin-coffee-tour-with-hotel-transfers-and-meals.a48310953.activity-details) ![Medellín: Comuna 13 District Tour with Cable Car Ride](https://mediaim.expedia.com/localexpert/4534339/806550ed-927d-43ad-8053-620e72efcb79.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Medellín: Comuna 13 District Tour with Cable Car Ride $27 per adult **98%** of travellers recommend [](https://expedia.com/things-to-do/medellin-comuna-13-district-tour-with-cable-car-ride.a4534339.activity-details) ![Rumbero Gastrotour through Medellín and Street Food](https://mediaim.expedia.com/localexpert/44887055/b06353e5-8ea4-46ba-8f02-725ae1f0ab0c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rumbero Gastrotour through Medellín and Street Food $33 per adult **92%** of travellers recommend [](https://expedia.com/things-to-do/rumbero-gastrotour-through-medellin-and-street-food.a44887055.activity-details) ![Coffee Tour In Horse Riding and Lunch In Medellin](https://mediaim.expedia.com/localexpert/2260401/a43164c0-0434-4a30-9191-e90bad861d8e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Coffee Tour In Horse Riding and Lunch In Medellin $99 per adult **96%** of travellers recommend [](https://expedia.com/things-to-do/coffee-tour-in-horse-riding-and-lunch-in-medellin.a2260401.activity-details) ![Medellin: Bike City Tour with Local Food and Drink Tastings](https://mediaim.expedia.com/localexpert/4575855/bd451d73-82e9-4500-809f-84ccb3315010.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Medellin: City Bike Tour with Colombian Drinks and Snacks $30 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/medellin-city-bike-tour-with-colombian-drinks-and-snacks.a4575855.activity-details) [See all activities in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d553248635976386952.Travel-Guide-Activities) ## Cities near Santa Cruz ![Botero Square Sculpture Park featuring a church or cathedral, a square or plaza and a city](https://images.trvl-media.com/place/6100414/19e02f13-b4cb-496a-97bd-2b19a64a936b.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Medellin ![Rock of Guatape featuring landscape views, mist or fog and a river or creek](https://images.trvl-media.com/place/6154953/04799058-a6ce-4962-b237-bd8bcc1ad277.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Medellín ![Amazing paragliding expedition spot. I'd recommend wearing long pants and a windbreaker -- it's cold up in the air.](https://images.trvl-media.com/place/6245393/a2c01bd6-e4e6-4ec4-8440-27a48f9732f0.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Bello - Cities near Santa Cruz - Places of interest [Medellin](https://expedia.com/Medellin.dx2246)[Medellín](https://expedia.com/Medellin.dx6140804)[Bello](https://expedia.com/Bello.dx6245393) - [El Tesoro Shopping Park ](https://expedia.com/El-Tesoro-Shopping-Park-El-Poblado.d6272368.Vacation-Attraction) - [Lleras Park ](https://expedia.com/Lleras-Park-El-Poblado.d6166214.Vacation-Attraction) - [Poblado Park ](https://expedia.com/Poblado-Park-El-Poblado.d6160683.Vacation-Attraction) - [Atanasio Giradot Stadium ](https://expedia.com/Atanasio-Giradot-Stadium-Laureles-Estadio.d6100404.Vacation-Attraction) - [Santafé Mall ](https://expedia.com/Santafe-Mall-El-Poblado.d6160635.Vacation-Attraction) - [Plaza Mayor Convention Center ](https://expedia.com/Plaza-Mayor-Convention-Center-La-Candelaria.d6165872.Vacation-Attraction) - [Botero Plaza ](https://expedia.com/Botero-Plaza-La-Candelaria.d6100414.Vacation-Attraction) - [Pueblito Paisa ](https://expedia.com/Pueblito-Paisa-Medellin.d6272340.Vacation-Attraction) - [Medellín Clinic - El Poblado ](https://expedia.com/Medellin-Clinic-El-Poblado-El-Poblado.d553248635968064292.Vacation-Attraction) - [Oviedo Shopping Center ](https://expedia.com/Oviedo-Shopping-Center-El-Poblado.d6160633.Vacation-Attraction) - [Llanogrande Mall ](https://expedia.com/Llanogrande-Mall-Rionegro.d553248635949084833.Vacation-Attraction) - [Arvi Park ](https://expedia.com/Arvi-Park-Medellin.d6292534.Vacation-Attraction) - [El Retiro Park ](https://expedia.com/El-Retiro-Park-Retiro.d553248635949085035.Vacation-Attraction) - [Golden Mile ](https://expedia.com/Golden-Mile-El-Poblado.d553248635947667693.Vacation-Attraction) - [Centro Comercial Los Molinos ](https://expedia.com/Centro-Comercial-Los-Molinos-Belen.d688666727383367680.Vacation-Attraction) - [Universidad Pontificia Bolivariana ](https://expedia.com/Universidad-Pontificia-Bolivariana-Laureles.d6302256.Vacation-Attraction) - [Medellin Botanical Garden ](https://expedia.com/Medellin-Botanical-Garden-Aranjuez.d6272363.Vacation-Attraction) - [University of Antioquia ](https://expedia.com/University-Of-Antioquia-Aranjuez.d6100424.Vacation-Attraction) - [Second Laureles Park ](https://expedia.com/Second-Laureles-Park-Laureles.d553248621563219923.Vacation-Attraction) - [Parque Rionegro ](https://expedia.com/Parque-Rionegro-San-Antonio-de-Prado.d553248621532467210.Vacation-Attraction) - [Unicentro Shopping Center ](https://expedia.com/Unicentro-Shopping-Center-Laureles.d553248635931205169.Vacation-Attraction) - [Antioquia Museum ](https://expedia.com/Antioquia-Museum-La-Candelaria.d6100418.Vacation-Attraction) - [Hospital Pablo Tobon Uribe ](https://expedia.com/Hospital-Pablo-Tobon-Uribe-Robledo.d6302147.Vacation-Attraction) - [Parques del Río Medellín ](https://expedia.com/Parques-Del-Rio-Medellin-Laureles-Estadio.d553248635976547095.Vacation-Attraction) - [San Nicolás Mall ](https://expedia.com/San-Nicolas-Mall-Rionegro.d553248635188837460.Vacation-Attraction) - [EAFIT University ](https://expedia.com/EAFIT-University-El-Poblado.d6302254.Vacation-Attraction) - [Medellin Cathedral ](https://expedia.com/Medellin-Cathedral-La-Candelaria.d6100412.Vacation-Attraction) - [Las Vegas Clinic ](https://expedia.com/Las-Vegas-Clinic-El-Poblado.d553248635968064527.Vacation-Attraction) - [Somer Clinic ](https://expedia.com/Somer-Clinic-Rionegro.d553248635976333500.Vacation-Attraction) - [Hospital Universitario San Vicente de Paul ](https://expedia.com/Hospital-Universitario-San-Vicente-De-Paul-La-Candelaria.d6302151.Vacation-Attraction) - [Sabaneta Park ](https://expedia.com/Sabaneta-Park-Sabaneta.d735273771463077888.Vacation-Attraction) - [Complex Llanogrande Shopping Center ](https://expedia.com/Complex-Llanogrande-Shopping-Center-Rionegro.d644120205384843264.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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