Title: Santo Domingo Vacation Rentals from $78: Search Short-Term Rentals | Expedia.com

[Santo Domingo Travel Guide](https://expedia.com/Santo-Domingo.dx829297286067531776)[Hotels in Santo Domingo](https://expedia.com/Santo-Domingo-Hotels.d829297286067531776.Travel-Guide-Hotels)[Flights to Santo Domingo](https://expedia.com/Cheap-Flights-To-Santo-Domingo.d829297286067531776.Travel-Guide-Flights)[Car Rentals in Santo Domingo](https://expedia.com/Car-Rentals-In-Santo-Domingo.d829297286067531776.Car-Rental-Guide)[Santo Domingo Vacation Packages](https://expedia.com/Santo-Domingo.d829297286067531776.Destination-Travel-Guides)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=829297286067531776&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=829297286067531776&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=829297286067531776&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=829297286067531776&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santo Domingo vacation rentals

![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104240000/104238700/104238611/54243bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104240000/104238700/104238611/07678224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104240000/104238700/104238611/61f80c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104240000/104238700/104238611/a8ef691f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Volcano View Cottage

[](https://www.expedia.com/Nueva-California-Hotels-Volcano-View-Cottage.h104238611.Hotel-Information)

Volcán

9.4/10

Exceptional

(3 reviews)

"I was alone, but this casita would be perfect for a couple. The owner, Antonio, was quick to respond to any issues. I would definitely stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John E.

$83 nightly

$83 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Nueva-California-Hotels-Volcano-View-Cottage.h104238611.Hotel-Information)

![Deluxe Studio Suite, 1 Queen Bed, Ocean View | View from room](https://images.trvl-media.com/lodging/114000000/113880000/113873200/113873181/7f52d0b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/114000000/113880000/113873200/113873181/e9142f0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach nearby, black sand, 2 beach bars](https://images.trvl-media.com/lodging/114000000/113880000/113873200/113873181/3861a0d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Studio Suite, 1 Queen Bed, Ocean View | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/114000000/113880000/113873200/113873181/ae0f2bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Perla Pacifico

[](https://www.expedia.com/Puerto-Armuelles-Hotels-Perla-Pacifico.h113873181.Hotel-Information)

Puerto Armuelles

$89 nightly

$98 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Puerto-Armuelles-Hotels-Perla-Pacifico.h113873181.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/70000000/69820000/69818100/69818042/6f178945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/70000000/69820000/69818100/69818042/df02c8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/70000000/69820000/69818100/69818042/c4b535c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/70000000/69820000/69818100/69818042/3b6ef66c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas Mountain View

[](https://www.expedia.com/Volcan-Hotels-Vrbo-Property.h69818042.Hotel-Information)

Volcán

$120 nightly

$130 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Volcan-Hotels-Vrbo-Property.h69818042.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/70000000/69820000/69818400/69818323/e83f142f_edited_f1b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/70000000/69820000/69818400/69818323/e597967b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/70000000/69820000/69818400/69818323/18de1893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/70000000/69820000/69818400/69818323/d633a108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas Mountain View, near to the national park Volcan Baru

[](https://www.expedia.com/Volcan-Hotels-Cabanas-Mountain-View.h69818323.Hotel-Information)

Volcán

8.0/10

Very Good

(1 review)

"Basic but nice small cottage which was perfect for relaxing near Volcan."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paquita B.

$95 nightly

$102 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Volcan-Hotels-Cabanas-Mountain-View.h69818323.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/116000000/115360000/115355000/115354980/b45826af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115360000/115355000/115354980/e74f4daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/116000000/115360000/115355000/115354980/d99a7db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/116000000/115360000/115355000/115354980/53ec40db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Copeyhousechiriquí

[](https://www.expedia.com/La-Concepcion-Hotels-Copey-House-Chiriqui.h115354980.Hotel-Information)

Volcán

$75 nightly

$78 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/La-Concepcion-Hotels-Copey-House-Chiriqui.h115354980.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/101000000/100330000/100329700/100329697/cc879186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/101000000/100330000/100329700/100329697/4b4a4bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/101000000/100330000/100329700/100329697/0ed766f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/101000000/100330000/100329700/100329697/500085a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spectacular beachfront apartment, Spacious terrace with an unparalleled view.

[](https://www.expedia.com/Palo-Grande-Hotels-Spectacular-Beachfront-Apartment.h100329697.Hotel-Information)

Palo Grande

$135 nightly

$135 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Palo-Grande-Hotels-Spectacular-Beachfront-Apartment.h100329697.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19&regionId=829297286067531776&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santo+Domingo%2C+Chiriqu%C3%AD+Province%2C+Panama&regionId=829297286067531776&latLong=8.489657%2C-82.736783&adults=2&startDate=2026-06-02&d1=2026-06-02&endDate=2026-06-05&d2=2026-06-05&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santo+Domingo%2C+Chiriqu%C3%AD+Province%2C+Panama&regionId=829297286067531776&latLong=8.489657%2C-82.736783&adults=2&startDate=2026-06-02&d1=2026-06-02&endDate=2026-06-05&d2=2026-06-05&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santo+Domingo%2C+Chiriqu%C3%AD+Province%2C+Panama&regionId=829297286067531776&latLong=8.489657%2C-82.736783&adults=2&startDate=2026-06-02&d1=2026-06-02&endDate=2026-06-05&d2=2026-06-05&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santo+Domingo%2C+Chiriqu%C3%AD+Province%2C+Panama&regionId=829297286067531776&latLong=8.489657%2C-82.736783&adults=2&startDate=2026-06-02&d1=2026-06-02&endDate=2026-06-05&d2=2026-06-05&lodging=CONDO)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santo+Domingo%2C+Chiriqu%C3%AD+Province%2C+Panama&regionId=829297286067531776&latLong=8.489657%2C-82.736783&adults=2&startDate=2026-06-02&d1=2026-06-02&endDate=2026-06-05&d2=2026-06-05&lodging=COTTAGE)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=Santo+Domingo%2C+Chiriqu%C3%AD+Province%2C+Panama&regionId=829297286067531776&latLong=8.489657%2C-82.736783&adults=2&startDate=2026-06-02&d1=2026-06-02&endDate=2026-06-05&d2=2026-06-05&lodging=CHALET)

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## Top Santo Domingo Hotel Reviews

![Los Brezos Boutique Hotel](https://images.trvl-media.com/lodging/70000000/69410000/69404700/69404636/0830ff2c_y.jpg)

### Los Brezos Boutique Hotel

10/10 Excellent

"Excellent choice for your stay in Volcan. I stayed for 2 nights as solo traveler. Great staff and management. Everyone was helpful and friendly. Volcan is a great base for exploring Cerro Punto region for a day or 2\. I highly recommend this hotel. "

[](https://expedia.com/Volcan-Hotels-Hotel-Los-Brezos.h69404636.Hotel-Information)

![Private room at Las Brisas Del Mar](https://images.trvl-media.com/lodging/34000000/33560000/33552900/33552811/9641acd4_y.jpg)

### Private room at Las Brisas Del Mar

10/10 Excellent

"This is the perfect place to stay if you like early morning walks on the beach to enjoy the sunrise, animals (dogs, cats, toucans), and a peaceful relaxing setting. Don & Sandy were so sweet and welcoming in sharing their beautiful home. We loved that the whole house is solar powered and the entire house including pool had filtered water through ozone which was amazing. The beds are comfortable and bathrooms spacious. The house is very secure with two gates to enter. It can be a little hard to find but Don was very accommodating to help us find our way and once there you can pin the location on Google Maps. This is a great place to stay if you don't mind some shared spaces and enjoy meeting new people! They did give us our own kitchen space in the outside kitchen area, and we had a private room and bathroom."

[](https://expedia.com/Puerto-Armuelles-Hotels-Private-Room-At-Las-Brisas-Del-Mar.h33552811.Hotel-Information)

![Hotel Bambito By Faranda Boutique, a member of Radisson Individuals](https://images.trvl-media.com/lodging/2000000/1700000/1691400/1691326/e018a7d8_y.jpg)

### Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

10/10 Excellent

"Everything very good, Great staff! Beautiful and relaxing place"

[](https://expedia.com/Volcan-Hotels-Hotel-Bambito-Resort-By-Faranda-Boutique.h1691326.Hotel-Information)

![Hotel Dos Rios](https://images.trvl-media.com/lodging/17000000/16220000/16210700/16210674/440fb046_y.jpg)

### Hotel Dos Rios

10/10 Excellent

"Beautiful place, we stayed in The junior room it was nice to have the balcony. Very clean "

[](https://expedia.com/Volcan-Hotels-Hotel-Dos-Rios.h16210674.Hotel-Information)

![Big Daddy's Beach Club and Hotel](https://images.trvl-media.com/lodging/21000000/20160000/20156400/20156333/09c3f5a0_y.jpg)

### Big Daddy's Beach Club and Hotel

10/10 Excellent

"Highly recommended. Only thing is the water flow in the shower in my room was weak and showering is not enjoyable. "

[](https://expedia.com/Puerto-Armuelles-Hotels-Big-Daddys-Beach-Club-And-Hotel.h20156333.Hotel-Information)

![Las Olas Resort](https://images.trvl-media.com/lodging/1000000/970000/967300/967264/d4734dda_y.jpg)

### Las Olas Resort

10/10 Excellent

"The property is well kept, lush gardens, hummingbirds galore! Restaurant La Abigail is 5 star with 3 star prices. We loved Las Olas and will be back! "

[](https://expedia.com/Palo-Grande-Hotels-Las-Olas-Resort.h967264.Hotel-Information)

![Little Italy B&B](https://images.trvl-media.com/lodging/13000000/12340000/12333800/12333732/b28fbef6_y.jpg)

### Little Italy B&B

10/10 Excellent

"Convenient to reach from Concepcion "

[](https://expedia.com/Boqueron-Hotels-Bed-And-Breakfast-Little-Italy.h12333732.Hotel-Information)

## Find out more about Santo Domingo

**Everything you need to know about Santo Domingo vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santo Domingo vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santo Domingo vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santo Domingo vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santo Domingo. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santo Domingo in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $78 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santo Domingo rentals**

At Expedia, we put the best Santo Domingo vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santo Domingo rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santo Domingo vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santo Domingo. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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- [Cottages in Santo Domingo ](https://expedia.com/Santo-Domingo-Cottages.d829297286067531776-aaCottages.Travel-Guide-Accommodation)

## Frequently asked questions

### Are there vacation rentals in Santo Domingo?

### What are some of the best vacation home rentals in Santo Domingo?

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Hotels

- [Hotels in Chiriqui](https://expedia.com/Chiriqui-Hotels.d6051578.Travel-Guide-Hotels)
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- [Hotels in El Bongo](https://expedia.com/El-Bongo-Hotels.d829296855796961280.Travel-Guide-Hotels)

Flights

- [Cheap Flights to Chiriqui](https://expedia.com/Cheap-Flights-To-Chiriqui.d6051578.Travel-Guide-Flights)
- [Cheap Flights to Dominical](https://expedia.com/Cheap-Flights-To-Dominical.d829297245579923456.Travel-Guide-Flights)
- [Cheap Flights to Santa Clara](https://expedia.com/Cheap-Flights-To-Santa-Clara.d828935412002074624.Travel-Guide-Flights)
- [Cheap Flights to Cerro Punta](https://expedia.com/Cheap-Flights-To-Cerro-Punta.d6245726.Travel-Guide-Flights)
- [Cheap Flights to Boca Chica](https://expedia.com/Cheap-Flights-To-Boca-Chica.d6198033.Travel-Guide-Flights)
- [Cheap Flights to David](https://expedia.com/Cheap-Flights-To-David.d500195.Travel-Guide-Flights)
- [Cheap Flights to Boquete](https://expedia.com/Cheap-Flights-To-Boquete.d500194.Travel-Guide-Flights)

Cars

- [Car rentals in Boquete](https://expedia.com/Car-Rentals-In-Boquete.d500194.Car-Rental-Guide)
- [convertible Car Rentals in Chiriqui](https://expedia.com/Convertible-Car-Rentals-In-Chiriqui.d6051578-tConvertible.Car-Rental-Guide-Class)
- [Car rentals in David](https://expedia.com/Car-Rentals-In-David.d500195.Car-Rental-Guide)
- [Car rentals in Santa Marta](https://expedia.com/Car-Rentals-In-Santa-Marta.d829297271869829120.Car-Rental-Guide)
- [pickup Car Rentals in Chiriqui](https://expedia.com/Pickup-Car-Rentals-In-Chiriqui.d6051578-tPickup.Car-Rental-Guide-Class)

Activities

- [Things to do in Boquete](https://expedia.com/Things-To-Do-In-Boquete.d500194.Travel-Guide-Activities)
- [Things to do in David](https://expedia.com/Things-To-Do-In-David.d500195.Travel-Guide-Activities)
- [Things to do in Volcan](https://expedia.com/Things-To-Do-In-Volcan.d6053182.Travel-Guide-Activities)

Packages

- [Volcan Vacation](https://expedia.com/Volcan.d6053182.Destination-Travel-Guides)
- [Boca Chica Vacation](https://expedia.com/Boca-Chica.d6198033.Destination-Travel-Guides)
- [Boquete Vacation](https://expedia.com/Boquete.d500194.Destination-Travel-Guides)

Vacation Rentals

- [Boquete Vacation Rentals](https://expedia.com/Boquete-Vacation-Rentals.d500194.Travel-Guide-VacationRentals)

General

- [Visit Boqueron](https://expedia.com/Boqueron.dx6348570)
- [Visit Boca Chica](https://expedia.com/Boca-Chica.dx6198033)
- [Visit Alanje](https://expedia.com/Alanje.dx829296792219693056)
- [Visit Cerro Punta](https://expedia.com/Cerro-Punta.dx6245726)
- [Visit Río Sereno](https://expedia.com/Rio-Sereno.dx829296881617084416)

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