Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Jun 5 - Jun 7
In two months
Jul 17 - Jul 19
In three months
Aug 14 - Aug 16
In four months
Sep 11 - Sep 13

Our top choices for Santa Cruz vacation rentals

Exterior

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (18 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
$49 nightly
The price is $54
Jun 8 - Jun 9
Total with taxes and fees
Linda Vista Cabins
Family House, 2 Bedrooms, Garden View | 3 bedrooms, minibar, desk, free WiFi

Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
$69 nightly
The price is $76
May 20 - May 21
Total with taxes and fees
Casa Little Italy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel Dos Rios

Hotel Dos Rios

8/10 Good
"Great staff, really enjoyed each and everyone, but one must remember where in the world they are. The hotel is on well tended gardens, nothing spectacular, but remember where you are. Unfortunately they need to upgrade, maybe it’s not possible, who am I to assume? One, two days max is enough, we actually left for other areas for the day. Just a note the food is average but not bad,drinks are amazing. "
Laurie 4-night trip
Posted 2 days ago
Hotel Dos Rios

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $54 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we give you a choice of vacation rentals near top local attractions in Santa Cruz, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Santa Cruz has to offer?

Potrerillos Ranch close to Boquete : This vacation home rental outside of Santa Cruz is located in the mountains and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Santa Cruz?

While you're exploring the area, Las Cavernas de Corredores and Área Silvestre Protegida Lagunas de Volcán are a couple of picturesque spots to get outside and enjoy nature. Barriles and Paradise Tropical Garden are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

A vacation rental is a private property you can book for a couple of days or more in Santa Cruz. Vacation rentals provide amenities like kitchens and laundry facilities so you'll have everything you want. If you're concerned about a clean environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a family trip.