Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Feb 20 - Feb 22
In two months
Apr 3 - Apr 5
In three months
May 1 - May 3
In four months
May 29 - May 31

Our top choices for Santa Cruz vacation rentals

Exterior

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
$56 nightly
The price is $62
Feb 8 - Feb 9
Total with taxes and fees
Linda Vista Cabins
Family House, 2 Bedrooms, Garden View | 3 bedrooms, minibar, desk, free WiFi

Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
$75 nightly
The price is $83
Feb 6 - Feb 7
Total with taxes and fees
Casa Little Italy
Interior

Copeyhousechiriquí

Copeyhousechiriquí
Volcán
$75 nightly
The price is $78
Mar 7 - Mar 8
Total with taxes and fees
Copeyhousechiriquí
Property grounds

Cabañas Mountain View

Cabañas Mountain View
Volcán
$120 nightly
The price is $130
Feb 7 - Feb 8
Total with taxes and fees
Cabañas Mountain View
Exterior

Cabin inside cloudforest “PILA” floor 1

Cabin inside cloudforest “PILA” floor 1
Cerro Punta
$190 nightly
The price is $190
Feb 6 - Feb 7
Total with taxes and fees
Cabin inside cloudforest “PILA” floor 1
Outdoor pool

ADVENTURE House in Ibiza Beach Residences – Beach House in Coclé

ADVENTURE House in Ibiza Beach Residences – Beach House in Coclé
Río Hato
$193 nightly
The price is $193
Feb 8 - Feb 9
Total with taxes and fees
ADVENTURE House in Ibiza Beach Residences – Beach House in Coclé
Exterior

Cabañas Mountain View, near to the national park Volcan Baru

Cabañas Mountain View, near to the national park Volcan Baru
Volcán
8.0 out of 10, Very Good, (1 review)
"Basic but nice small cottage which was perfect for relaxing near Volcan."
United States
Paquita B.
$95 nightly
The price is $102
Mar 1 - Mar 2
Total with taxes and fees
Cabañas Mountain View, near to the national park Volcan Baru
Living area

Cabin in Cerro Punta 6BR, Fireplace, Hiking

Cabin in Cerro Punta 6BR, Fireplace, Hiking
Cerro Punta
$532 nightly
The price is $532
Feb 8 - Feb 9
Total with taxes and fees
Cabin in Cerro Punta 6BR, Fireplace, Hiking
Exterior

Eco-Cabin apartment inside Cloudforest

Eco-Cabin apartment inside Cloudforest
Cerro Punta
$201 nightly
The price is $201
Feb 6 - Feb 7
Total with taxes and fees
Eco-Cabin apartment inside Cloudforest
Property grounds

Unique eco-cabin inside cloudforest “PILA”

Unique eco-cabin inside cloudforest “PILA”
Cerro Punta
$267 nightly
The price is $267
Feb 6 - Feb 7
Total with taxes and fees
Unique eco-cabin inside cloudforest “PILA”
Interior

Cabin inside International Park “PILA”

Cabin inside International Park “PILA”
Cerro Punta
$190 nightly
The price is $190
Feb 6 - Feb 7
Total with taxes and fees
Cabin inside International Park “PILA”
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa

10/10 Excellent
"Staff was amazing, local foods excellent. Perfect location for hiking the vertical farms and bird watching!"
David 2-night trip
Posted 4 days ago
Los Quetzales Ecolodge & Spa

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $62 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we give you a choice of vacation rentals near top local attractions in Santa Cruz, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Santa Cruz has to offer?

Casa Little Italy: This vacation home rental outside of Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

What’s there to see and do in Santa Cruz?

While you're exploring the area, Las Cavernas de Corredores and Área Silvestre Protegida Lagunas de Volcán are a couple of picturesque spots to get outside and enjoy nature. Barriles and Arte Cruz Volcán are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

A vacation rental is a private property you can book for a couple of days or more in Santa Cruz. Vacation rentals provide amenities like kitchens and laundry facilities so you'll have everything you want. If you're concerned about a clean environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a family trip.