Beginning of main content

Santorini Luxury Hotels

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Santorini Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Santorini Neighborhoods for Luxury Hotels

Fira
36 hotels
from

$401

Imerovigli
30 hotels

Dreams Luxury Suites

5.0 out of 5.0
from

$597

Oia
34 hotels
from

$878

Featured Santorini Luxury Hotels

See all 885 Hotels in Santorini
The Majestic Hotel

The Majestic Hotel

Fira, Santorini
5.0 out of 5.0
4.5 out of 5 (168 reviews)
Love Love this hotel !!!! The staff is very nice and friendly highly recommended
  Jul 15, 2017

$320

$320
Andronis Boutique Hotel

Andronis Boutique Hotel

Oia, Santorini
5.0 out of 5.0
4.9 out of 5 (48 reviews)
Little piece of heavenExperience of a lifetime! Andronis provides indescribably beautiful views of the caldera. Everything was perfect. The staff are available 24-7 to assist you with anything you may possibly need. If you ask for something, it comes right away. Need a reservation or a recommendation? They will take care ...
  Jun 13, 2017

$795

$795
Andronis Luxury Suites

Andronis Luxury Suites

Oia, Santorini
5.0 out of 5.0
4.8 out of 5 (53 reviews)
Amazing with great hospitality Lovely reception, amazing service and great food. We did not have any question unanswered and all suggestions would ere just matching our expectations...
  Jul 10, 2017

$878

$878
Aressana Spa Hotel and Suites

Aressana Spa Hotel and Suites

Fira, Santorini
4.0 out of 5.0
4.8 out of 5 (100 reviews)
RockStar quality!Amazing hotel in the heart of Fira. The staff and the rooms are amazing, an oasis in the middle of crowded chaos!
  Jul 20, 2017

$401

$401
Volcano View Hotel & Villas

Volcano View Hotel & Villas

Fira, Santorini
5.0 out of 5.0
4.5 out of 5 (139 reviews)
Celestia Grand Villas were amazing!We stayed in the Celestia Grand Villas, which is part of the hotel complex. We found everything we needed to be in our villa or it would be provided if we asked. Breakfast on our private terrace overlooking the caldera was an amazing experience, the food choice was amazing with a great variety and ...
  Jul 12, 2017

$285

$285
Dreams Luxury Suites

Dreams Luxury Suites

Imerovigli, Santorini
5.0 out of 5.0
4.9 out of 5 (16 reviews)
Very nice Enjoy the facility and the good location. Staffs are all very helpful and friendly
  Jul 22, 2017

$597

$597
Santorini Princess Luxury Spa Hotel

Santorini Princess Luxury Spa Hotel

Imerovigli, Santorini
5.0 out of 5.0
4.9 out of 5 (236 reviews)
Lovely hotel, lovely people!We had an amazing time at this lovely piece of heaven! From the moment we arrived, we were treated like family. Georgia welcomed us and took more than a moment to first make sure I was comfortable as I had sustained an injury at the airport after our arrival. She and Rafaela were delightfully warm ...
  Jul 13, 2017

$246

$246
Ambassador Aegean Luxury Hotel and Suites

Ambassador Aegean Luxury Hotel and Suites

Akrotiri, Santorini
5.0 out of 5.0
4.6 out of 5 (48 reviews)
Beautiful hotel and private locatoinOur family of 4 spent 5 days at this hotel. The staff were excellent and special shout out to Pepi (concierge) and Effi (dining room) for excellent service. We would definitely recommend this hotel as it is well appointed, has beautiful views, and is in a more private part of the island.
  Jun 27, 2017

$651

$651
San Antonio

San Antonio

Imerovigli, Santorini
4.0 out of 5.0
4.8 out of 5 (28 reviews)
What an amazing hotelBooked this for my girlfriend and myself for end of May / Start of June 2017 and what a place to say. Room was lovely, always cleaned from top to bottom. Staff friendly, approachable and willing to help and show their personality and have a chat. Pool is gorgeous, but beware, it's not heated at all ...
  Jun 11, 2017

$604

$604
Astro Palace

Astro Palace

Eikostis Pemptis Martiou, Santorini
5.0 out of 5.0
4.6 out of 5 (187 reviews)
Beautiful hotel, perfect locationIt was like being at home but with the hotel luxury !
  Jul 8, 2017

$306

$306
Map

Recently booked Santorini hotels

Honeymoon Petra Villas
4.0 out of 5.0
Last booking: 6 hours ago
Blue Dolphins Apartments & Suites
3.0 out of 5.0
Last booking: 6 hours ago
Panorama Boutique Hotel
4.0 out of 5.0
Last booking: 7 hours ago
San Antonio
4.0 out of 5.0
Last booking: 8 hours ago
Santo Maris Oia, Luxury Suites & Spa
5.0 out of 5.0
Last booking: 9 hours ago
Anemomilos Suites
2.0 out of 5.0
Last booking: 10 hours ago
Aegean Plaza Hotel
4.0 out of 5.0
Last booking: 10 hours ago
Dream Island Hotel
3.0 out of 5.0
Last booking: 13 hours ago
Villa Iliovasilema Santorini
3.0 out of 5.0
Last booking: 13 hours ago

A weekend away keeps your stress at bay, so pack your luggage for Santorini and get ready to relax. Brilliant activities, divine eats, and some of the world’s most stunning photo opportunities: these are just some of the things you'll love about in Santorini. You'll treat yourself to the city's best food, get in line to see the coolest sites, and enjoy the most popular performances. Where else would you stay but a luxury hotel? Extravagant experiences are right up your alley, so get your luxury hotel in Santorini on Expedia.com today and start your trip off on the right (well-dressed) foot.

5-Star Vacations in Santorini

If you need any proof that Santorini is full of an intoxicating assortment of activities, keep in mind that plenty of folks love it enough to call it home. No matter what brings you to Santorini, the destination always delivers. Santorini is full of dreamy hotels on top of appealing attractions, so you can count on a spectacular stay. Book early to get the best room!

Your luxury vacation is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your travel on Expedia.com, you never have to limit yourself. Thanks to our unbeatable prices on hotels, your bucket list budget will always be intact. After many hours of exploration, your luxury suite awaits. Take advantage of amenities like an oversized bathtub or hot tub before the day is over. The luxury hotels in Santorini will lull you into a state of bliss in no time.

Find Luxury Santorini Hotels Now

It's that time; you're prepared to get swept away in Santorini, and Expedia.com is here to make the process painless. Browse the wealth of ratings and reviews on dozens of hotels until you spot the perfect place to stay. Luxury accommodations offer amenities like stately suites and VIP services. Many luxe accommodations in Santorini even feature impeccable suites, and it's likely you'll discover incredible in-house dining in your hotel. Use our easy booking widget to find and book a fabulous 5-star hotel in Santorini, and soon you'll be soaking up luxury in style!