A calm lake surrounded by trees and vegetation.

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Our top choices for Southwest Illinois hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.
A compact kitchenette with a refrigerator and an ice dispenser.

1. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Steven
$120 nightly
$131 total
Oct 26 - Oct 27
Total with taxes and fees
Best Western U. S. Inn
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.
A spacious lobby with a large seating area, a reception desk, and a television.
A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.
An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

2. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
United States
Jeremy
$139 nightly
$156 total
Oct 26 - Oct 27
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites
A hotel room with a bed, a desk with a computer, a TV, and a wardrobe.
A patio area with outdoor seating, including chairs and tables, and a covered area with umbrellas.
A breakfast buffet area with a display of cinnamon sweet rolls, a sign indicating the roll selection, and a patterned wall in the background.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

3. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
Sparta
United States
NADINE
$94 nightly
$104 total
Nov 22 - Nov 23
Total with taxes and fees
Holiday Inn Express Hotel & Suites Sparta by IHG
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.
A bar area with a long counter, multiple chairs, and hanging light fixtures.

4. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Richard
$110 nightly
$124 total
Oct 31 - Nov 1
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.
A bathroom with a sink, toilet, and a stack of towels.
A room with teal walls, a wooden desk, a chair, a television, a lamp, a microwave, and a coat rack.
A motel with a prominent 'MOTEL' sign.

5. Powhatan Motel

Powhatan Motel
Pocahontas
United States
Gene
$97 nightly
$103 total
Oct 26 - Oct 27
Total with taxes and fees
Powhatan Motel
A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.
A wooden wall with the sign "THE PRINCIPAL HOTEL" and a row of books below.
A restaurant with multiple tables and booths, large windows, and a modern interior design.
A hotel named "The Principal Hotel" with a brick facade, multiple windows, and a parking lot in front.

6. The Principal Hotel

The Principal Hotel
Columbia
United States
Jeffrey
$100 nightly
$111 total
Nov 18 - Nov 19
Total with taxes and fees
The Principal Hotel
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.
A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.
A hotel room with a sofa, two lamps, a television, and a desk.

7. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
United States
Jeffrey
$94 nightly
$104 total
Oct 26 - Oct 27
Total with taxes and fees
Seasons Inn & Suites Highland
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.
A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.
A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.
A hotel with a covered entrance, multiple rooms, and a parking lot.

8. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
Mount Vernon
United States
Ryan
$72 nightly
$82 total
Nov 1 - Nov 2
Total with taxes and fees
Quality Inn Mount Vernon, IL
A hotel room with a large bed, two bedside tables with lamps, a window with curtains, a painting on the wall, and a radiator.
A furnished living room with a sofa, a wooden table, a TV, and a desk with a computer.
A building with a sign reading "Lake Tree Inn & Suites" and a picnic table in front.
A small kitchen area with a coffee machine, a trash bin, and a potted plant.

9. Laketree Inn And Suites Marion

Laketree Inn And Suites Marion
Marion
United States
Karen
$72 nightly
$80 total
Oct 26 - Oct 27
Total with taxes and fees
Laketree Inn And Suites Marion
A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.
A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.
A hotel reception area with a long wooden counter, coffee machines, and a wall with framed pictures.
A reception desk with a wooden panel design, a large 'C' logo, and a glass partition.

10. Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
Greenville
United States
Debbie
$98 nightly
$109 total
Nov 18 - Nov 19
Total with taxes and fees
Comfort Inn & Suites Greenville I-70
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

11. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
Tad
$81 nightly
$90 total
Nov 1 - Nov 2
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.
A modern hotel room with a living area, a kitchenette, and a door leading to another room.
A spacious lobby with a modern design, featuring a large seating area with leather chairs, a kitchen area with a counter and appliances, and a flat-screen TV mounted on the wall.
A hotel room with a large bed, a desk with a chair, a sofa, and a TV.

12. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
Mascoutah
United States
Alice
$101 nightly
$115 total
Nov 1 - Nov 2
Total with taxes and fees
Best Western Plus MidAmerica Hotel
A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.
An outdoor patio area with tables and chairs, large windows, and a stone wall.
A hotel room with two beds, a large window, and a wall-mounted lamp.
A vending machine area with various drinks and snacks.

13. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
Doug
$114 nightly
$129 total
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express & Suites Mount Vernon by IHG
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.
A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.
A lobby with patterned sofas, a fireplace, and framed pictures on the wall.
An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

14. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
O'Fallon
United States
Karissa
$101 nightly
$117 total
Nov 9 - Nov 10
Total with taxes and fees
Drury Inn & Suites St. Louis O'Fallon, IL
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.
A hotel room with two beds, a television, a desk, and a window with curtains.
A hotel room with a bed, a desk, a chair, a TV, a lamp, and a flower arrangement.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

15. Red Bud Country Inn

Red Bud Country Inn
Red Bud
United States
James
$98 nightly
$108 total
Oct 26 - Oct 27
Total with taxes and fees
Red Bud Country Inn
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.
A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.
A hotel room with a large bathtub, a desk with a chair, and a bed.
A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

16. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
United States
Susan
$100 nightly
$113 total
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A small, clean room with a microwave, a vending machine, and a table with chairs.
A hotel room with two beds, a small kitchenette, and a dining area.
A self-service laundry station with multiple washing machines, a price tag of $1.50, and a sign indicating guest services at the lobby.
A reception area with a wooden counter, a tiled floor, and a wall with framed pictures.

17. Rodeway Inn Mount Vernon, IL

Rodeway Inn Mount Vernon, IL
Mount Vernon
United States
Zach
$65 nightly
$75 total
Oct 26 - Oct 27
Total with taxes and fees
Rodeway Inn Mount Vernon, IL
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A modern bar area with a large screen, seating, and gaming machines.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

18. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Ron
$115 nightly
$128 total
Oct 26 - Oct 27
Total with taxes and fees
Walker's Bluff Casino Resort
A Best Western hotel with a parking lot and a covered entrance.
A gym with treadmills, ellipticals, and weight machines.
A spacious lobby with a sofa, chairs, a coffee table, and a dining area with tables and chairs.
A hotel room with a bed, a television, a desk, a coffee machine, and a bathroom visible through an open door.

19. Best Western Marion Hotel

Best Western Marion Hotel
Marion
United States
Cornell
$77 nightly
$92 total
Oct 26 - Oct 27
Total with taxes and fees
Best Western Marion Hotel
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

20. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Kenneth
$119 nightly
$134 total
Oct 30 - Oct 31
Total with taxes and fees
DoubleTree by Hilton Mt. Vernon
View all properties

Hotels recommended for families in Southwest Illinois

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.
A compact kitchenette with a refrigerator and an ice dispenser.

Best Western U. S. Inn

Best Western U. S. Inn
Nashville
$120 nightly
$131 total
Oct 26 - Oct 27
Total with taxes and fees
Best Western U. S. Inn
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.
A spacious lobby with a large seating area, a reception desk, and a television.
A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.
An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
$139 nightly
$156 total
Oct 26 - Oct 27
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.
A bar area with a long counter, multiple chairs, and hanging light fixtures.

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
$110 nightly
$124 total
Oct 31 - Nov 1
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.
An outdoor patio area with tables and chairs, large windows, and a stone wall.
A hotel room with two beds, a large window, and a wall-mounted lamp.
A vending machine area with various drinks and snacks.

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
$114 nightly
$129 total
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express & Suites Mount Vernon by IHG
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
$81 nightly
$90 total
Nov 1 - Nov 2
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
$119 nightly
$134 total
Oct 30 - Oct 31
Total with taxes and fees
DoubleTree by Hilton Mt. Vernon
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.
A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.
A hotel room with a large bathtub, a desk with a chair, and a bed.
A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
$100 nightly
$113 total
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A modern bar area with a large screen, seating, and gaming machines.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
$115 nightly
$128 total
Oct 26 - Oct 27
Total with taxes and fees
Walker's Bluff Casino Resort
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Stay near popular Southwest Illinois attractions

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

DuQuoin State Fairgrounds

8.2/10 (95 reviews)
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."
Photo by throwingsofas

Top Southwest Illinois Hotel Reviews

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

10/10 Excellent
"Clean and nice. Comfortable beds. Would definitely stay here again."
Doug 1-night trip
Posted 1 hour ago
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Drury Inn & Suites Marion

Drury Inn & Suites Marion

8/10 Good
"Everything was great. The mattress isn’t very comfortable but that’s the only thing. I’d still stay again."
Christina 1-night trip
Posted 5 hours ago
Drury Inn & Suites Marion
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Clean room, nice pool, good breakfast"
Midhat 3-night trip
Posted 6 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

8/10 Good
"It was an okay stay. Staff was helpful, room was clean and decent."
Jasmine 1-night trip
Posted 6 hours ago
Quality Inn & Suites near St. Louis and I-255
Best Western Marion Hotel

Best Western Marion Hotel

10/10 Excellent
"Overall stay and room conditions were acceptable. Only feedback to give was that the sink had low water pressure."
Niko 3-night trip
Posted 14 hours ago
Best Western Marion Hotel
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent
"Clean and quiet with nice staff and a great breakfast and coffee."
Sam 1-night trip
Posted 2 days ago
Drury Inn & Suites St. Louis Collinsville
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

10/10 Excellent
"The only downfall was the indoor pool. I thought it would be heated. It wasn't. The kids still went in but we're shivering."
Michele 3-night trip
Posted 5 days ago
Quality Inn O'Fallon - St. Louis - Shiloh

More cheap stays in Southwest Illinois

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
$51 nightly
$59 total
Nov 1 - Nov 2
Total with taxes and fees
6.6/10 (1,149 reviews)
Super 8 by Wyndham O'Fallon
Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2431 Old Country Inn Dr Caseyville IL
$59 nightly
$67 total
Oct 26 - Oct 27
Total with taxes and fees
Motel 6 Caseyville, IL - Caseyville Il
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

1607 Pontiac Dr East St. Louis IL
$73 nightly
$83 total
Nov 11 - Nov 12
Total with taxes and fees
7.4/10 Good! (1,001 reviews)
Quality Inn & Suites near St. Louis and I-255
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL
$88 nightly
$100 total
Oct 28 - Oct 29
Total with taxes and fees
7.4/10 Good! (141 reviews)
Best Western St. Louis Fairview Heights
Seasons Inn & Suites Highland

Seasons Inn & Suites Highland

20 Central Blvd Highland IL
$94 nightly
$104 total
Oct 26 - Oct 27
Total with taxes and fees
8/10 Very Good! (697 reviews)
Seasons Inn & Suites Highland
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL
$88 nightly
$106 total
Nov 8 - Nov 9
Total with taxes and fees
Country Inn & Suites by Radisson, Marion, IL

Hotels in Southwest Illinois with star-rating

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