A calm lake surrounded by trees and vegetation.

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Our top choices for Southwest Illinois hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.
A hotel room with two beds, a desk, and a window with a view.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

1. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Steven
$120 nightly
$131 total
Oct 27 - Oct 28
Total with taxes and fees
Best Western U. S. Inn
A hotel reception desk with a digital display, a desk phone, and a computer. There is a sign indicating the hotel's name and services.
A hotel room with a bed, a desk with a computer, a TV, and a wardrobe.
A buffet with various food items, including omelets and other dishes, arranged on a counter with a patterned tile backsplash.
A hot tub area with a view of the parking lot through a glass door.

2. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
Sparta
United States
NADINE
$100 nightly
$111 total
Nov 1 - Nov 2
Total with taxes and fees
Holiday Inn Express Hotel & Suites Sparta by IHG
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.
A hotel room with a large bed, a desk with a chair, a sofa, and a TV.
A modern hotel room with a living area, a kitchenette, and a door leading to another room.
A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

3. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
Mascoutah
United States
Alice
$101 nightly
$115 total
Nov 1 - Nov 2
Total with taxes and fees
Best Western Plus MidAmerica Hotel
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

4. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Richard
$110 nightly
$124 total
Nov 1 - Nov 2
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.
A motel with a prominent 'MOTEL' sign.
A bathroom with a sink, toilet, and a stack of towels.
A room with teal walls, a wooden desk, a chair, a television, a lamp, a microwave, and a coat rack.

5. Powhatan Motel

Powhatan Motel
Pocahontas
United States
Gene
$97 nightly
$103 total
Oct 27 - Oct 28
Total with taxes and fees
Powhatan Motel
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.
A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.
A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.

6. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
United States
Jeffrey
$124 nightly
$137 total
Oct 27 - Oct 28
Total with taxes and fees
Seasons Inn & Suites Highland
A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.
A hotel reception area with a long wooden counter, coffee machines, and a wall with framed pictures.
A hotel room with a blue armchair, a sofa, a bed, a desk, a television, and a window.
A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.

7. Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
Greenville
United States
Debbie
$100 nightly
$111 total
Nov 22 - Nov 23
Total with taxes and fees
Comfort Inn & Suites Greenville I-70
A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.
A modern kitchen with a central island, bar stools, and a dining area.
A hotel named "The Principal Hotel" with a brick facade, multiple windows, and a parking lot in front.
A wooden wall with the sign "THE PRINCIPAL HOTEL" and a row of books below.

8. The Principal Hotel

The Principal Hotel
Columbia
United States
Jeffrey
$98 nightly
$109 total
Nov 3 - Nov 4
Total with taxes and fees
The Principal Hotel
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.
A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.
A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.
A reception area with a desk, chairs, a red carpet, and a television mounted on the wall.

9. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
Mount Vernon
United States
Ryan
$72 nightly
$82 total
Nov 1 - Nov 2
Total with taxes and fees
Quality Inn Mount Vernon, IL
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A hallway with vending machines and a carpeted floor.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

10. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
Tad
$81 nightly
$90 total
Nov 1 - Nov 2
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake
A hotel room with a large bed, two bedside tables with lamps, a window with curtains, a painting on the wall, and a radiator.
A furnished living room with a sofa, a wooden table, a TV, and a desk with a computer.
A sign for Lake Tree Inn & Suites with a welcome message for fishermen and internet access.
A hotel room with a television on a wooden cabinet, a floor lamp, a green sofa, and a small table.

11. Laketree Inn And Suites Marion

Laketree Inn And Suites Marion
Marion
United States
Karen
$73 nightly
$81 total
Oct 28 - Oct 29
Total with taxes and fees
Laketree Inn And Suites Marion
A hotel with a covered entrance, stone pillars, and a modern design.
A multi-story hotel with a brick facade, large windows, and a gated entrance.
A spacious lobby with a wooden floor, a reception desk, and a seating area with chairs.
A hotel room with two beds, a large window, and a wall-mounted lamp.

12. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
Doug
$114 nightly
$129 total
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express & Suites Mount Vernon by IHG
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.
A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.
A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.
A spacious lobby with a large seating area, a reception desk, and a television.

13. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
United States
Jeremy
$139 nightly
$156 total
Oct 27 - Oct 28
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.
A modern hotel lobby with seating areas, including sofas and chairs, and a large window with blinds.
A lobby with patterned sofas, a fireplace, and framed pictures on the wall.
A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.

14. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
O'Fallon
United States
Karissa
$101 nightly
$117 total
Nov 9 - Nov 10
Total with taxes and fees
Drury Inn & Suites St. Louis O'Fallon, IL
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.
A hotel room with two beds, a television, a desk, and a window with curtains.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A Country Inn Motel sign, a parking lot, and a building with an American flag.

15. Red Bud Country Inn

Red Bud Country Inn
Red Bud
United States
James
$98 nightly
$108 total
Oct 27 - Oct 28
Total with taxes and fees
Red Bud Country Inn
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.
A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.
A hotel room with a large bathtub, a desk with a chair, and a bed.
A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

16. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
United States
Susan
$100 nightly
$113 total
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A modern bar area with a large screen, seating, and gaming machines.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.

17. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Ron
$118 nightly
$131 total
Oct 28 - Oct 29
Total with taxes and fees
Walker's Bluff Casino Resort
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.
An outdoor patio area with tables and chairs, large windows, and red umbrellas.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

18. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Kenneth
$119 nightly
$134 total
Oct 30 - Oct 31
Total with taxes and fees
DoubleTree by Hilton Mt. Vernon
A small, clean room with a microwave, a vending machine, and a table with chairs.
A reception area with a wooden counter, a tiled floor, and a wall with framed pictures.
A bathroom with a shower, a bathtub, and a toilet.
A hotel room with two beds, a small kitchenette, and a dining area.

19. Rodeway Inn Mount Vernon, IL

Rodeway Inn Mount Vernon, IL
Mount Vernon
United States
Zach
$65 nightly
$75 total
Oct 27 - Oct 28
Total with taxes and fees
Rodeway Inn Mount Vernon, IL
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A reception area with a counter, a clock, and a chandelier.
A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.
A breakfast buffet with various pastries, a bowl of oranges, and a waffle batter dispenser.

20. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
Mount Vernon
United States
Leslie
$66 nightly
$75 total
Nov 1 - Nov 2
Total with taxes and fees
Super 8 by Wyndham Mt. Vernon IL
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Hotels recommended for families in Southwest Illinois

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.
A hotel room with two beds, a desk, and a window with a view.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

Best Western U. S. Inn

Best Western U. S. Inn
Nashville
$120 nightly
$131 total
Oct 27 - Oct 28
Total with taxes and fees
Best Western U. S. Inn
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.
A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.
A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.
A spacious lobby with a large seating area, a reception desk, and a television.

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
$139 nightly
$156 total
Oct 27 - Oct 28
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
$110 nightly
$124 total
Nov 1 - Nov 2
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
A hotel with a covered entrance, stone pillars, and a modern design.
A multi-story hotel with a brick facade, large windows, and a gated entrance.
A spacious lobby with a wooden floor, a reception desk, and a seating area with chairs.
A hotel room with two beds, a large window, and a wall-mounted lamp.

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
$114 nightly
$129 total
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express & Suites Mount Vernon by IHG
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A hallway with vending machines and a carpeted floor.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
$81 nightly
$90 total
Nov 1 - Nov 2
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.
An outdoor patio area with tables and chairs, large windows, and red umbrellas.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
$119 nightly
$134 total
Oct 30 - Oct 31
Total with taxes and fees
DoubleTree by Hilton Mt. Vernon
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.
A hotel lobby with a reception desk, a red sofa, a potted plant, and a fireplace.
A hotel room with a large bathtub, a desk with a chair, and a bed.
A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Mount Vernon
$100 nightly
$113 total
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A modern bar area with a large screen, seating, and gaming machines.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
$118 nightly
$131 total
Oct 28 - Oct 29
Total with taxes and fees
Walker's Bluff Casino Resort
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Stay near popular Southwest Illinois attractions

Giant City State Park

9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

World Wide Technology Raceway

9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

DuQuoin State Fairgrounds

8.2/10 (95 reviews)
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."
Photo by throwingsofas

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent
"It was a busy weekend, but parking was a breeze. The breakfast area was lively but totally manageable."
Robert 1-night trip
Posted 1 hour ago
Drury Inn & Suites St. Louis Collinsville
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Great room, Happy Hour food, cocktails and employees . We loved the bar, very warm and inviting. Bartender was wonderful, wish I remembered her name. The only negative is that breakfast doesn’t start until 7:00 am on weekends. A little earlier would be nice for those of us that like to hit the trail earlier or maybe a grab and go option. Would defiantly recommend!"
Carol 1-night trip
Posted 3 hours ago
Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"The staff was awesome! The bathroom however had some stains on the shower curtain. It should have been washed . The bed was so very comfortable! We slept great! Thank you… The staff came right to the room when we couldn’t get the tv remote to work. Asked if we needed anything else.."
Michael 2-night trip
Posted 5 hours ago
Quality Inn O'Fallon - St. Louis - Shiloh
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

10/10 Excellent
"Clean and nice. Comfortable beds. Would definitely stay here again."
Doug 1-night trip
Posted 23 hours ago
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Clean room, nice pool, good breakfast"
Midhat 3-night trip
Posted 1 day ago
Drury Inn & Suites St. Louis O'Fallon, IL
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

8/10 Good
"It was an okay stay. Staff was helpful, room was clean and decent."
Jasmine 1-night trip
Posted 1 day ago
Quality Inn & Suites near St. Louis and I-255
Best Western Marion Hotel

Best Western Marion Hotel

10/10 Excellent
"Overall stay and room conditions were acceptable. Only feedback to give was that the sink had low water pressure."
Niko 3-night trip
Posted 2 days ago
Best Western Marion Hotel
Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

10/10 Excellent
"Pleasantly surprised at what a nice place this was. Easy check in/checkout. Indoor pool is nice, decent size. Excellent location for highways, stores, restaurants etc. Walking distance to Golden Corral Breakfast is good because of the waffle machine"
Laura 1-night trip
Posted 5 days ago
Super 8 by Wyndham Troy IL/St. Louis Area

More cheap stays in Southwest Illinois

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
$51 nightly
$59 total
Nov 1 - Nov 2
Total with taxes and fees
6.6/10 (1,150 reviews)
Super 8 by Wyndham O'Fallon
Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2431 Old Country Inn Dr Caseyville IL
$59 nightly
$67 total
Oct 27 - Oct 28
Total with taxes and fees
Motel 6 Caseyville, IL - Caseyville Il
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

1607 Pontiac Dr East St. Louis IL
$71 nightly
$81 total
Oct 28 - Oct 29
Total with taxes and fees
7.4/10 Good! (1,002 reviews)
Quality Inn & Suites near St. Louis and I-255
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL
$88 nightly
$100 total
Oct 28 - Oct 29
Total with taxes and fees
Best Western St. Louis Fairview Heights
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL
$92 nightly
$111 total
Nov 8 - Nov 9
Total with taxes and fees
Country Inn & Suites by Radisson, Marion, IL
Seasons Inn & Suites Highland

Seasons Inn & Suites Highland

20 Central Blvd Highland IL
$124 nightly
$137 total
Oct 27 - Oct 28
Total with taxes and fees
8/10 Very Good! (698 reviews)
Seasons Inn & Suites Highland

Hotels in Southwest Illinois with star-rating

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