Southwestern Virginia Vacations from $433
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Your Southwestern Virginia Vacation
Embark on your next thrilling adventure with a Southwestern Virginia vacation package, and leave knowing the finer details are already organized. Plus with the ability to customize your getaway, it'll be one you won't forget. Your trip to Southwestern Virginia wouldn't be complete without getting to some of its most renowned cities, starting with Roanoke. A couple of the top attractions here include Berglund Center and Valley View Mall. Wytheville is another favorite with Southwestern Virginia travelers. Visitors to this destination enjoy Fort Chiswell Animal Park and Galewinds Amusement Park. From the instant you book your Southwestern Virginia vacation to the second you come back home, Expedia has you covered each step of the way.
The Latest Southwestern Virginia vacation packages
Price found within the past 48 hours. Click for updated prices.
Julian Price House
Fisher Park
Price was $1,832, price is now $527 per person
$527
per person
Nov 6 - Nov 9
found 5 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
10/10 Exceptional! (102 reviews)
The staff was very detailed and organized with my arrival being that I flew in from KY at midnight. The interior and exterior design is EXQUISITE! My communication with the staff was always very pleasant and professional via text. I will be booking another stay the next time I’m in NC.
Reviewed on Aug 15, 2025
O.Henry Hotel
Price was $878, price is now $640 per person
$640
per person
Nov 6 - Nov 9
found 5 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Greensboro (GSO)
9.8/10 Exceptional! (685 reviews)
The design of the hotel and the special events like Jazz night and Tea in the afternoon were a delight.
Reviewed on Jul 21, 2025
Don't see what you're looking for?
See all available trips from Columbus to Southwestern Virginia
View all tripsWhere to stay in Southwestern Virginia
Find the best Southwestern Virginia areas and neighborhoods for the activities you enjoy most. Learn more about Southwestern Virginia
Downtown Roanoke
While visiting Downtown Roanoke, you might make a stop by sights like Center in the Square and Taubman Museum of Art.
Discover the most popular places to visit in Southwestern Virginia
Virginia Tech University
4.5/5(580 reviews)
Enjoy the collegiate vibe around Virginia Tech University, a top college in Blacksburg. You can attend a sporting event while in the area.
Lane Stadium
5/5(153 reviews)
Catch an event at Lane Stadium during your trip to Blacksburg. You can attend a sporting event while in the area.
Grayson Highlands State Park
4.5/5(38 reviews)
You can take time to visit Grayson Highlands State Park during your travels to Mouth of Wilson. Wander the parks or discover the area's mountain views.
Southwestern Virginia Hotel Deals
The Inn at Virginia Tech and Skelton Conference Center
901 Prices Fork Road, Blacksburg, VA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $120 total per night from Aug 28 to Aug 29
$120 total
Aug 28 - Aug 29
Total includes taxes and fees
9.4/10 Exceptional! (1,006 reviews)
"Nice hotel on campus."
Reviewed on Aug 17, 2025
Extended Stay America Suites - Bristol
134 Salem Drive, Bristol, VA
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $70 total per night from Aug 28 to Aug 29
$70 total
Aug 28 - Aug 29
Total includes taxes and fees
7.2/10 Good! (1,005 reviews)
"Billy, our check in host was great, but the bathroom needed a little love. It was clean but had a leaky faucet in the tub. It was good for just an overnight stay"
Reviewed on Aug 17, 2025
Country Inn & Suites by Radisson, Roanoke, VA
7860 Plantation Rd, Roanoke, VA
Fully refundable
$100 nightly
The price is $113 total per night from Sep 4 to Sep 5
$113 total
Sep 4 - Sep 5
Total includes taxes and fees
9/10 Wonderful! (1,871 reviews)
Fam trip
"This is my fav hotel in Roanoke. It is always clean and quiet and they have sausage gravy and biscuits for breakfast."
Reviewed on Aug 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.