Book a Hotel + Flight or Car together to unlock savings
Plan, book, travel with confidence
Better together
Save up to $2,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Your Upstate South Carolina Vacation
With a Upstate South Carolina vacation package, you can forget about the stress of planning and simply focus on experiencing what this thrilling destination has on offer. With so much to do and see on a trip to Upstate South Carolina, it can be hard to know where to begin. Kick off your travels in Greenville at Falls Park on the Reedy and Bon Secours Wellness Arena — two popular attractions here. Another top city worthy of a spot on your itinerary is Spartanburg. Don't miss WestGate Mall and Tyger River Park. Expedia is your one-stop shop for planning your Upstate South Carolina vacation. From hotels and flights, to car rentals and more, we're here to help you create a travel experience like no other.
The Latest Upstate South Carolina Vacation Packages
Price found within the past 48 hours. Click for updated prices.
"The Restoration has ruined us for staying anywhere else in Asheville! Location is perfect; close enough to walk to our favorite bars, restaurants, and shopping. We also love the fact that if we don’t want to leave the hotel for food or nightlife, we don’t have to! The Observatory is perfect for intimate, cozy drinks, and bowling and live music at The Draftsman is a great end to the night!"
Discover the most popular places to visit in Upstate South Carolina
Clemson University
Rating: 9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
You can make plans for a show at The Peace Center during your stay in Greenville. Amble around this family-friendly area's riverfront or attend a sporting event.
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.
Address: 895 Spartan Blvd, Spartanburg, SC, 29301-1372, US
Location: 22.8 mi from Upstate South Carolina
Star rating: 2.5/5
Guest rating: 9/10 (Wonderful, 819 reviews)
Price: $102 nightly, $113 total, Dec 13 - Dec 14, Total with taxes and fees
Review: IHG is doing a wonderful job with staff quality and friendliness everyone was very nice, and said hello at every opportunity. Clean rooms, good beds, and nice breakfast. Thanks we will be back
Address: 801 Spartan Blvd, Spartanburg, SC, 29301-1372, US
Location: 22.5 mi from Upstate South Carolina
Star rating: 2.5/5
Guest rating: 8.6/10 (Excellent, 1004 reviews)
Price: $101 nightly, $112 total, Dec 11 - Dec 12, Total with taxes and fees
Review: My only complaint was getting text messages about checking in through the app and receiving a digital key, “bypassing the front desk.” However, when I followed the steps, I received a message to see a staff member at the front desk. Very disappointing and frustrating.
Address: 670 Verdae Blvd, Greenville, SC, 29607-4022, US
Location: 8.4 mi from Upstate South Carolina
Star rating: 3.5/5
Guest rating: 9/10 (Wonderful, 1483 reviews)
Price: $108 nightly, $120 total, Nov 23 - Nov 24, Total with taxes and fees
Review: Indoor pool was cold - the rooms/bathrooms look straight out of the 90’s. Breakfast was great though! Not worth the money in my opinion. Better options available
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
