Title: The Best 5 Star Hotels in Clarksville, IN from $135 | Expedia.com [Clarksville Travel Guide](https://expedia.com/Clarksville.dx9727)[Hotels in Clarksville](https://expedia.com/Clarksville-Hotels.d9727.Travel-Guide-Hotels)[Vacation Rentals in Clarksville](https://expedia.com/Clarksville-Vacation-Rentals.d9727.Travel-Guide-VacationRentals)[Flights to Clarksville](https://expedia.com/Cheap-Flights-To-Clarksville.d9727.Travel-Guide-Flights)[Things to do in Clarksville](https://expedia.com/Things-To-Do-In-Clarksville.d9727.Travel-Guide-Activities)[Car Rentals in Clarksville](https://expedia.com/Car-Rentals-In-Clarksville.d9727.Car-Rental-Guide)[Clarksville Vacation Packages](https://expedia.com/Clarksville.d9727.Destination-Travel-Guides) ![View of Louisville from the Falls of the Ohio at Golden Hour. #BVSblue](https://images.trvl-media.com/place/3108/df34b2a2-a0fe-4fea-b211-931e06d4c702.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Eric O ![](https://images.trvl-media.com/place/3108/df34b2a2-a0fe-4fea-b211-931e06d4c702.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Clarksville 5 Star Hotels Tonight [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=9727&startDate=2026-02-07&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 8 - Feb 9](https://www.expedia.com/Hotel-Search?regionId=9727&startDate=2026-02-08&endDate=2026-02-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=9727&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=9727&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Clarksville 5-star hotels ![Interior entrance](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/56e486f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/81948b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/00819013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite | Terrace/patio](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/2ccf1a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Louisville Bourbon Inn [](https://www.expedia.com/Louisville-Hotels-Louisville-Bourbon-Inn.h101176472.Hotel-Information) Old Louisville 10/10 Exceptional (21 reviews) "Absolutely the best B&B we have ever stayed with." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roy $265 nightly $308 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Louisville-Hotels-Louisville-Bourbon-Inn.h101176472.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Clarksville-Hotels.s50-0-d9727.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Clarksville-Hotels.s50-0-d9727.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Clarksville. ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galt House Hotel Trademark Collection by Wyndham 140 North Fourth Street Louisville KY $151 nightly $178 total Mar 1 - Mar 2 Total with taxes and fees 8.8/10 Excellent! (4,040 reviews) [](https://expedia.com/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Omni Louisville Hotel](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Omni Louisville Hotel 400 S. 2nd Street Louisville KY $207 nightly $244 total Feb 8 - Feb 9 Total with taxes and fees 9.2/10 Wonderful! (1,769 reviews) [](https://expedia.com/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Embassy Suites Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Embassy Suites Louisville Downtown 501 South Fourth Street Louisville KY $115 nightly $135 total Feb 15 - Feb 16 Total with taxes and fees 8.8/10 Excellent! (1,149 reviews) [](https://expedia.com/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) Still don't see what you're looking for? [See all properties in Clarksville.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9727&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9727&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9727&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9727&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9727&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F8%2F2026&endDate=2%2F9%2F2026®ionId=9727&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Clarksville Stroll along the Ohio River at the Falls of the Ohio State Park, where fossil beds and hiking trails await. Catch a show at the historic Clarksville Little Theatre or browse unique shops in the charming downtown area. [See all hotels in Clarksville](https://www.expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22&adults=2®ionId=9727) ![View of Louisville from the Falls of the Ohio at Golden Hour. #BVSblue](https://images.trvl-media.com/place/3108/df34b2a2-a0fe-4fea-b211-931e06d4c702.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high) Photo by Eric O ## Top Clarksville Hotel Reviews ## Find out more about Clarksville Ready for an incredible adventure? Add even more luxury on your next trip to Clarksville by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Clarksville so popular in the last year. There's no reason to delay a getaway to Clarksville any longer. Besides, the accommodations in Clarksville offer great customer service, averaging 3.5 in our ranking system, so you know you're in good hands. Reserve one of our 5-star hotels in Clarksville and indulge in the finer things in life for a while. What are you waiting for? ### 5-Star Hotels in Clarksville You can expect superior customer service from your hotel. Spa treatments, delicious meals, and attentive guest service are all at your fingertips. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Clarksville offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. What creature comforts do you want in your lodging? A reflexology treatment that will leave you feeling like a million bucks? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A deep-tissue massage to help your cares fall away? Don't want to take our word for it? Then explore the 219 reviews various guests have left on Expedia and get to know these places. But you aren't going to spend your entire vacation in your room, of course. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Clarksville are waiting for you to rest up after a busy day. ### Your Getaway Starts Today The results are in, and Clarksville 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Decide on one of our Clarksville 5-star hotels today and settle down in total tranquility tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Clarksville? > - Search for the lowest price per night from $135 ### What makes a hotel 5 stars in Clarksville? ### Are there any 5-star all-inclusive resorts in Clarksville? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [4 Star Hotels in Jeffersonville - Clarksville ](https://www.expedia.com/4Star-Jeffersonville-Clarksville-Hotels.s40-0-d6059638.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Jeffersonville - Clarksville ](https://www.expedia.com/5Star-Jeffersonville-Clarksville-Hotels.s50-0-d6059638.Travel-Guide-Filter-Hotels) - [Hotels near Atlantis Waterpark ](https://www.expedia.com/Atlantis-Waterpark-Hotels.0-l553248621532656248-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Jeffersonville - Clarksville ](https://www.expedia.com/Jeffersonville-Clarksville-Hotels-Cheap-Hotels.0-0-d6059638-tCheapHotels.Travel-Guide-Filter-Hotels) - 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