Find hotels in Barrio La Isabelita, Santo Domingo

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Discover Barrio La Isabelita hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Apartment, 2 Bedrooms, Smoking, City View | Balcony
Safe and Economical, for a Long Time

Safe and Economical, for a Long Time

3.0 star property
Barrio La Isabelita
$46 nightly
The price is $52
Dec 7 - Dec 8
Total with taxes and fees
Safe and Economical, for a Long Time
Apartment, 2 Bedrooms, Smoking, Balcony | Interior
Bright and Youth Condo With hot Water

Bright and Youth Condo With hot Water

2.5 star property
Barrio La Isabelita
$44 nightly
The price is $50
Dec 2 - Dec 3
Total with taxes and fees
Bright and Youth Condo With hot Water
Outdoor pool, pool umbrellas, sun loungers
W&P Santo Domingo

W&P Santo Domingo

4.0 star property
6.2 mi from Barrio La Isabelita
9.2 out of 10, Wonderful, (1153)
"Love staying here"
United States
Cecil
$73 nightly
The price is $94
Jan 1 - Jan 2, 2026
Total with taxes and fees
W&P Santo Domingo
Front of property
Catalonia Santo Domingo

Catalonia Santo Domingo

5.0 star property
4.5 mi from Barrio La Isabelita
8.8 out of 10, Excellent, (1721)
" MANAGMENT Front desk staff,Restaurant staff are Amazing!.Breakfast excellent!"
United States
Alejandro
$96 nightly
The price is $123
Jan 1 - Jan 2, 2026
Total with taxes and fees
Catalonia Santo Domingo
Property amenity
El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel

5.0 star property
6.1 mi from Barrio La Isabelita
9.2 out of 10, Wonderful, (1290)
"Great stay "
United States
Nelson
$100 nightly
The price is $128
Dec 31 - Jan 1, 2026
Total with taxes and fees
El Embajador, a Royal Hideaway Hotel
Outdoor pool, open 7:00 AM to 9:00 PM, sun loungers
Embassy Suites by Hilton Santo Domingo

Embassy Suites by Hilton Santo Domingo

4.0 star property
5.5 mi from Barrio La Isabelita
9.4 out of 10, Exceptional, (1020)
"The room layout was perfect"
United States
Alexia Andrea
$128 nightly
The price is $164
Dec 14 - Dec 15
Total with taxes and fees
Embassy Suites by Hilton Santo Domingo
Outdoor pool, pool umbrellas, sun loungers
Sheraton Santo Domingo Hotel

Sheraton Santo Domingo Hotel

4.0 star property
3.7 mi from Barrio La Isabelita
8.8 out of 10, Excellent, (1011)
"Super Nice Hotel"
United States
Augusto
$121 nightly
The price is $155
Dec 5 - Dec 6
Total with taxes and fees
Sheraton Santo Domingo Hotel
Snack bar
Weston Suites & Hotel

Weston Suites & Hotel

3.5 star property
5.8 mi from Barrio La Isabelita
7.6 out of 10, Good, (1009)
"nice hotel "
United States
Robert
$47 nightly
The price is $60
Jan 1 - Jan 2, 2026
Total with taxes and fees
Weston Suites & Hotel
Premium Suite, 1 Bedroom, Non Smoking | Hypo-allergenic bedding, down comforters, pillowtop beds, in-room safe
Radisson Hotel Santo Domingo

Radisson Hotel Santo Domingo

4.5 star property
5.5 mi from Barrio La Isabelita
8.6 out of 10, Excellent, (1022)
"We stayed here because it was close to the concert venue we were attending. Friendly staff very helpful, safe area to walk to and front venue."
United States
Olga
$76 nightly
The price is $97
Dec 5 - Dec 6
Total with taxes and fees
Radisson Hotel Santo Domingo
2 outdoor pools, free cabanas, pool umbrellas
Dominican Fiesta Hotel

Dominican Fiesta Hotel

4.0 star property
8.7 mi from Barrio La Isabelita
8.0 out of 10, Very Good, (2579)
"The staff were friendly, and approachable, great foods."
Canada
Antoine
$84 nightly
The price is $108
Jan 1 - Jan 2, 2026
Total with taxes and fees
Dominican Fiesta Hotel
Exterior
Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial

3.5 star property
2.7 mi from Barrio La Isabelita
8.8 out of 10, Excellent, (250)
"Great location"
United States
Lucesita
$89 nightly
The price is $114
Dec 2 - Dec 3
Total with taxes and fees
Mosquito Boutique Hotel Zona Colonial
Reception
Hotel Vicentina

Hotel Vicentina

3.0 star property
15.6 mi from Barrio La Isabelita
8.6 out of 10, Excellent, (722)
"The room was clean and courteous staff waking distance from Beach and restaurants, will go again."
United States
Jose
$56 nightly
The price is $72
Dec 2 - Dec 3
Total with taxes and fees
Hotel Vicentina
Exterior
Hostal Boutique 53

Hostal Boutique 53

3.0 star property
3.6 mi from Barrio La Isabelita
9.0 out of 10, Wonderful, (85)
"We enjoyed our stay and would return another time. "
United States
June
$32 nightly
The price is $38
Dec 8 - Dec 9
Total with taxes and fees
Hostal Boutique 53
Superior Premium Level Room | Room amenity
Barceló Santo Domingo

Barceló Santo Domingo

4.0 star property
4.5 mi from Barrio La Isabelita
8.6 out of 10, Excellent, (1352)
"Breakfast was excellent staff was excellent and very attentive Hotel clean and the maids clean all day keeping the hotel spotless"
United States
Norman
$75 nightly
The price is $96
Jan 1 - Jan 2, 2026
Total with taxes and fees
Barceló Santo Domingo
Front of property
Honky Tonk Colonial

Honky Tonk Colonial

3.0 star property
2.6 mi from Barrio La Isabelita
9.6 out of 10, Exceptional, (122)
"Quick and friendly staff"
United States
Asfaha
$46 nightly
The price is $55
Dec 2 - Dec 3
Total with taxes and fees
Honky Tonk Colonial
Superior Apartment, 2 Bedrooms | View from room
Parco del caribe

Parco del caribe

3.0 star property
15.4 mi from Barrio La Isabelita
9.0 out of 10, Wonderful, (238)
"Clean bedroom the staff was friendly "
United States
Efrain
$43 nightly
The price is $51
Dec 2 - Dec 3
Total with taxes and fees
Parco del caribe
Beach nearby, 10 beach bars
Hotel Garant & Suites

Hotel Garant & Suites

3.0 star property
15.6 mi from Barrio La Isabelita
8.6 out of 10, Excellent, (501)
"Staff very friendly and helpful "
United States
maria claribel
$49 nightly
The price is $63
Dec 2 - Dec 3
Total with taxes and fees
Hotel Garant & Suites
Restaurant
Homewood Suites by Hilton Santo Domingo, Dominican Republic

Homewood Suites by Hilton Santo Domingo, Dominican Republic

3.5 star property
6.4 mi from Barrio La Isabelita
9.4 out of 10, Exceptional, (692)
"Grest location, spacious room and excellent breakfast."
United States
Felix
$119 nightly
The price is $153
Dec 12 - Dec 13
Total with taxes and fees
Homewood Suites by Hilton Santo Domingo, Dominican Republic
2 bars/lounges
Empyrean Art Deco

Empyrean Art Deco

3.0 star property
2.7 mi from Barrio La Isabelita
9.2 out of 10, Wonderful, (79)
"Very convenient hotel located in the Colonial Zone. Easy to access many of the historical buildings or parks."
United States
Willie
$62 nightly
The price is $80
Dec 2 - Dec 3
Total with taxes and fees
Empyrean Art Deco
LED TV
Hotel Restaurant Hamilton

Hotel Restaurant Hamilton

3.0 star property
15.7 mi from Barrio La Isabelita
7.8 out of 10, Good, (176)
"Amenities "
United States
Peter
$45 nightly
The price is $58
Dec 2 - Dec 3
Total with taxes and fees
Hotel Restaurant Hamilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Barrio La Isabelita

Find the best Barrio La Isabelita areas and neighborhoods for the activities you enjoy most.
Fort Ozama featuring heritage elements

Zona Colonial

A romantic ambiance fills the air of one of the America’s oldest European settlements, a neighborhood known for its architectural masterpieces, bars and parks.

Piantini

Unique features of Piantini include the shopping and restaurants. Make a stop by Blue Mall or Acropolis Center while you're exploring the area.

Downtown Santo Domingo

Polígono Central boasts a mix of commercial and residential zones, with a high concentration of malls, banks, and international fast food chains. Enjoy daily sports activities at Club Paraiso and Club Naco, or explore the city via Santo Domingo Metro and OMSA bus system.

Alcazar de Colon featuring a square or plaza and a city

Ciudad Colonial

Discover the historic heart of Santo Domingo, where cobblestone streets like Calle Las Damas lead to landmarks such as Alcázar de Colón and Catedral de Santa María la Menor. Stroll along pedestrian-only Calle del Conde, and enjoy local shops and restaurants near Plaza de España.

Bella Vista

When in Bella Vista, you can plan a visit to Acropolis Center and Bella Vista Mall, some noteworthy sights in the nearby area.

Top Barrio La Isabelita Hotel Reviews

Hodelpa Nicolas de Ovando

Hodelpa Nicolas de Ovando

10/10 Excellent
"Sumamente acogedor y colonial."
Romualdo 1-night trip
Posted 15 hours ago
Hodelpa Nicolas de Ovando

Frequently asked questions

What is Barrio La Isabelita like?
Travelers will be sure to find plenty to entertain them in Santo Domingo Este's Barrio La Isabelita neighborhood. Consider a visit to Three Eyes National Park as part of your Barrio La Isabelita travel plans.
How many hotels can I expect to find in Barrio La Isabelita?
Expedia has 7 Barrio La Isabelita hotels and other accommodations, and one might make a good home base for venturing out into the greater Santo Domingo Este area.
If I need to cancel my hotel reservation in Barrio La Isabelita, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to review the best deals available in Barrio La Isabelita.
Where can I learn more about changing or cancelling my trip to Barrio La Isabelita?
For additional details about updating your trip to Barrio La Isabelita or cancelling it, click here.
What can I see and do in this Santo Domingo Este neighborhood?
Three Eyes National Park is an attraction you might want to check out while you're in Barrio La Isabelita. While you're out sightseeing, National Aquarium and Agua Splash Caribe Parque Acuatico are a couple of additional sights to visit in Santo Domingo Este.