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Vacation Rentals in Santiago

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Our top choices for Santiago vacation rentals

Terrapartment Cusco

Terrapartment Cusco
3.0 star property
Santiago
Terrapartment Cusco

Kallpa Cusco apartment

Kallpa Cusco apartment
Santiago
$56 nightly
The price is $56
Jan 1 - Jan 2, 2026
Kallpa Cusco apartment

Casa Turismo Terres la Mejor Opcion Para las Familias y Amigos

Casa Turismo Terres la Mejor Opcion Para las Familias y Amigos
Santiago
$100 nightly
The price is $100
Jan 1 - Jan 2, 2026
Casa Turismo Terres la Mejor Opcion Para las Familias y Amigos

Cozy standard quadruple room cusco

Cozy standard quadruple room cusco
Santiago
$80 nightly
The price is $80
Jan 1 - Jan 2, 2026
Cozy standard quadruple room cusco

Los Profesionales - Casa Completa a Solo 10 Minutos del Centro

Los Profesionales - Casa Completa a Solo 10 Minutos del Centro
2.0 star property
Santiago
$135 nightly
The price is $135
Jan 5 - Jan 6, 2026
Los Profesionales - Casa Completa a Solo 10 Minutos del Centro

Departamento Cusco.

Departamento Cusco.
Santiago
$64 nightly
The price is $64
Jan 1 - Jan 2, 2026
Departamento Cusco.

cozy two bedroom apartment cusco

cozy two bedroom apartment cusco
Santiago
$80 nightly
The price is $80
Jan 1 - Jan 2, 2026
cozy two bedroom apartment cusco

cozy standard triple room cusco

cozy standard triple room cusco
Santiago
$70 nightly
The price is $70
Jan 1 - Jan 2, 2026
cozy standard triple room cusco

Cozy standard twin room cusco

Cozy standard twin room cusco
Santiago
$150 nightly
The price is $150
Jan 1 - Jan 2, 2026
Cozy standard twin room cusco

Unuwasi Hotel & Villa

Unuwasi Hotel & Villa
3.5 star property
Calca
10.0 out of 10, Exceptional, (1)
$100 nightly
The price is $100
Jan 2 - Jan 3, 2026
Unuwasi Hotel & Villa

Tun Tun Secret Mountain Houses

Tun Tun Secret Mountain Houses
3.0 star property
Urubamba
$35 nightly
The price is $35
Jan 1 - Jan 2, 2026
Tun Tun Secret Mountain Houses

HOSTAL KINSA COCHA

HOSTAL KINSA COCHA
2.0 star property
Pisac
$80 nightly
The price is $80
Jan 1 - Jan 2, 2026
HOSTAL KINSA COCHA

Inti Samana

Inti Samana
3.0 star property
Cusco
$28 nightly
The price is $28
Jan 2 - Jan 3, 2026
Inti Samana

w Warm Casona w Beautiful Church Views

w Warm Casona w Beautiful Church Views
2.0 star property
Andahuaylillas
$115 nightly
The price is $115
Jan 4 - Jan 5, 2026
w Warm Casona w Beautiful Church Views

Kintu Apart Hotel

Kintu Apart Hotel
3.0 star property
Cusco
Kintu Apart Hotel

Zans Apartments Cusco

Zans Apartments Cusco
3.5 star property
Tahuantinsuyo
10.0 out of 10, Exceptional, (7)
"It was perfect. The hosts were so helpful and kind. It was a perfect place to stay. We enjoyed this place"
United States
Laurie
$105 nightly
The price is $105
Jan 6 - Jan 7, 2026
Zans Apartments Cusco

Las Margaritas Apart

Las Margaritas Apart
4.0 star property
San Antonio
$58 nightly
The price is $58
Jan 1 - Jan 2, 2026
Las Margaritas Apart

Apartment Centric Inti

Apartment Centric Inti
2.5 star property
Ttio Sur
$39 nightly
The price is $39
Jan 1 - Jan 2, 2026
Apartment Centric Inti

Intimate romantic retreat in the Sacred Valley of the Inkas.

Intimate romantic retreat in the Sacred Valley of the Inkas.
Arin
10.0 out of 10, Exceptional, (1)
"Good service, good space, super comfortable bed. They can provide taxi service at extra cost. Very safe and peaceful. "
United States
Ivan
$97 nightly
The price is $111
Jan 3 - Jan 4, 2026
Intimate romantic retreat in the Sacred Valley of the Inkas.

Inyawasi Aparthotel

Inyawasi Aparthotel
3.5 star property
Los Incas
6.0 out of 10, (2)
"Séjour 2nuits avec enfants arrivé vers 22h il faisait -1 la nuit et pas de chauffage pas suffisamment de couverture pas d’eau et personnel parle pas anglais "
France
Sylvie
$81 nightly
The price is $81
Jan 3 - Jan 4, 2026
Inyawasi Aparthotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santiago Hotel Reviews

Find out more about Santiago

Discover your perfect Santiago vacation rental with Expedia

How many vacation rentals are available in Santiago?


Expedia has plenty of vacation rentals to choose from in and around  Santiago, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santiago?


The selection of Santiago vacation rentals we have selected for you start as low as $35 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santiago?


Vacation rentals in Santiago come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santiago vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santiago?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santiago vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santiago?


Find vacation rentals in Santiago by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santiago.  


What amenities are available in a vacation rental in Santiago?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santiago vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santiago?   


Everytime is a great time to head to Santiago! Staying in a Santiago vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santiago. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santiago vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santiago, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santiago vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.  


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