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Vacation Rentals in St. Charles County

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Top Cities in St. Charles County

Our top choices for St. Charles County vacation rentals

1. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (184 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
$245 nightly
The price is $262
Aug 16 - Aug 17
Total with taxes and fees
The Lofts of North Main Street

2. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
$245 nightly
The price is $262
Aug 20 - Aug 21
Total with taxes and fees
Prime Loft of Main Street

3. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (67 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$245 nightly
The price is $262
Aug 16 - Aug 17
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street

4. Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!
St. Charles Historic District
10.0 out of 10, Exceptional, (131 reviews)
"Super cute property, fantastic location. Very well maintained and clean, would definitely stay here again. "
United States
Jason T.
$375 nightly
The price is $402
Aug 16 - Aug 17
Total with taxes and fees
Stunning 1890's Home - Sleeps 8!

5. St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (161 reviews)
"Very nice historical place "
United States
Shawntell C.
$260 nightly
The price is $278
Aug 19 - Aug 20
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!

6. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
$315 nightly
The price is $347
Aug 17 - Aug 18
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment

7. New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
St. Charles Historic District
9.6 out of 10, Exceptional, (79 reviews)
" This house was excellent. The neighborhood was so charming and it was close to everything. I would definitely stay here again."
United States
Mary M.
$536 nightly
The price is $606
Aug 17 - Aug 18
Total with taxes and fees
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

8. Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (82 reviews)
"We stayed at be night. It was an older cute home. We had no problems."
United States
Misty
$233 nightly
The price is $250
Aug 25 - Aug 26
Total with taxes and fees
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

9. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$200 nightly
The price is $220
Aug 23 - Aug 24
Total with taxes and fees
Historic Main Street Studio | Dog-Friendly

10. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
9.8 out of 10, Exceptional, (8 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$274 nightly
The price is $302
Aug 16 - Aug 17
Total with taxes and fees
Walk to Main | Pet-Friendly Yard & Workspace

11. Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.0 out of 10, Wonderful, (48 reviews)
"Great property, plenty of space, was very clean!"
United States
Will M.
$487 nightly
The price is $551
Aug 16 - Aug 17
Total with taxes and fees
Charming open 4bd and screen-in porch! Sleeps 10!

12. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (41 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
$371 nightly
The price is $408
Aug 16 - Aug 17
Total with taxes and fees
Historic Main St 2BR | Steps to Shops

13. Stylish 2BR Retreat - Concrete & Canopy

Stylish 2BR Retreat - Concrete & Canopy
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"The property was very nice and clean. We had issues with checking in due to we had the property address but not a room number. When I called the phone number on the property information sheet the person that answered the phone said the this was no longer the number for the host. My daughter found information on the website with the room number on it. We talked to a couple of other people staying at the same location that had the same problem. Right address with no room number issued. They...
United States
William T.
$269 nightly
The price is $296
Aug 17 - Aug 18
Total with taxes and fees
Stylish 2BR Retreat - Concrete & Canopy

14. Cottage on Historic Main Street- Low Cleaning fee

Cottage on Historic Main Street- Low Cleaning fee
St. Charles Historic District
10.0 out of 10, Exceptional, (20 reviews)
"Great location to Main Street. "
United States
Daneen H.
$289 nightly
The price is $309
Aug 23 - Aug 24
Total with taxes and fees
Cottage on Historic Main Street- Low Cleaning fee

15. HotTub-2br2b-near Historic Main Street

HotTub-2br2b-near Historic Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (15 reviews)
"Easy check in, very clean, great location. Amazing hot tub! Perfect for a girl's weekend!"
United States
Kara A.
$306 nightly
The price is $328
Aug 18 - Aug 19
Total with taxes and fees
HotTub-2br2b-near Historic Main Street

16. Historic 1908 Frenchtown Home

Historic 1908 Frenchtown Home
St. Charles Historic District
8.8 out of 10, Excellent, (26 reviews)
"yes the kitchen was fully equipped."
Canada
David M.
$286 nightly
The price is $315
Aug 18 - Aug 19
Total with taxes and fees
Historic 1908 Frenchtown Home

17. Historic 1805 Main Street 2BR

Historic 1805 Main Street 2BR
St. Charles Historic District
9.6 out of 10, Exceptional, (42 reviews)
"The location is excellent. "
United States
McRay H.
$315 nightly
The price is $347
Aug 17 - Aug 18
Total with taxes and fees
Historic 1805 Main Street 2BR

18. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
$255 nightly
The price is $286
Aug 16 - Aug 17
Total with taxes and fees
6th street 101 - Walk to Main St

19. Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (9 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
$271 nightly
The price is $290
Aug 24 - Aug 25
Total with taxes and fees
Cottage on Main st- Low Cleaning Fee

20. The Oak & Aura Retreat

The Oak & Aura Retreat
St. Charles Historic District
8.0 out of 10, Very Good, (2 reviews)
"Great location, and very clean! Would stay here again!"
United States
Rachel B.
$300 nightly
The price is $331
Aug 17 - Aug 18
Total with taxes and fees
The Oak & Aura Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles County Hotel Reviews

Find out more about St. Charles County

Discover your perfect St. Charles County vacation rental with Expedia

How many vacation rentals are available in St. Charles County?


Expedia has plenty of vacation rentals to choose from in and around  St. Charles County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in St. Charles County?


The selection of St. Charles County vacation rentals we have selected for you start as low as $70 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in St. Charles County?


Vacation rentals in St. Charles County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of St. Charles County vacation rentals to suit everyone. 


Why should I choose a vacation rental in St. Charles County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A St. Charles County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in St. Charles County?


Find vacation rentals in St. Charles County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in St. Charles County.  


What amenities are available in a vacation rental in St. Charles County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in St. Charles County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in St. Charles County?   


Everytime is a great time to head to St. Charles County! Staying in a St. Charles County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in St. Charles County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect St. Charles County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in St. Charles County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your St. Charles County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.