A bridge over a calm river with a sunset sky.

Vacation Rentals in St. Charles County

Top Cities in St. Charles County

Our top choices for St. Charles County vacation rentals

Adorable Augusta Cabin

Adorable Augusta Cabin
Augusta
8.4 out of 10, Very Good, (18 reviews)
"Great little Cabin exactly as described. Weekend getaway with the wife clean and cozy. Would stay again if visiting the wineries "
United States
Michael W.
$179 nightly
The price is $200
Jun 30 - Jul 1
Total with taxes and fees
Adorable Augusta Cabin

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
9.8 out of 10, Exceptional, (6 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$251 nightly
The price is $276
Jul 16 - Jul 17
Total with taxes and fees
Duplex Hideaway in St. Charles, MO

The Blake Cottage Wine Country Home

The Blake Cottage Wine Country Home
Augusta
8.4 out of 10, Very Good, (11 reviews)
"It was a wonderful location for our girls' night! Plenty of room for our group and within walking distance of the wineries. "
United States
Deana T.
$379 nightly
The price is $422
Jul 13 - Jul 14
Total with taxes and fees
The Blake Cottage Wine Country Home

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (175 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
$241 nightly
The price is $258
Jun 30 - Jul 1
Total with taxes and fees
The Lofts of North Main Street

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.0 out of 10, Wonderful, (34 reviews)
"From the welcome email with clear concise directions on how to enter with door codes to a dwelling that had everything I needed with a very comfortable bed, it was a great stay and I wanted for nothing."
United States
Jacob G.
$179 nightly
The price is $197
Jun 30 - Jul 1
Total with taxes and fees
Stay on Main Historic Studio

Cozy 3 Bedroom/ Family Comfort & Convenient Location

Cozy 3 Bedroom/ Family Comfort & Convenient Location
Wentzville
10.0 out of 10, Exceptional, (6 reviews)
"We had a wonderful stay! The home was very clean, check-in was super easy, and it was the perfect place for our family. Everything was exactly as described and we felt comfortable the entire time. Would definitely stay here again!"
United States
Tricia W.
$328 nightly
The price is $353
Jun 30 - Jul 1
Total with taxes and fees
Cozy 3 Bedroom/ Family Comfort & Convenient Location

Rustic Augusta Wood Cabin

Rustic Augusta Wood Cabin
Augusta
9.6 out of 10, Exceptional, (8 reviews)
"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "
United States
teresa s.
$302 nightly
The price is $337
Jul 5 - Jul 6
Total with taxes and fees
Rustic Augusta Wood Cabin

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Augusta
10.0 out of 10, Exceptional, (34 reviews)
"Comfortable place to stay. We appreciated the snacks and that there is a pack n play!"
United States
Samantha E.
$268 nightly
The price is $286
Jun 30 - Jul 1
Total with taxes and fees
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

Spacious 2 Bedroom Townhome

Spacious 2 Bedroom Townhome
Saint Charles
8.0 out of 10, Very Good, (16 reviews)
"Quiet area and clean rooms"
United States
Chelsie H.
$254 nightly
The price is $279
Jul 2 - Jul 3
Total with taxes and fees
Spacious 2 Bedroom Townhome

King Suite. Free Breakfast. Pool & Gym. Your Next Trip!

King Suite. Free Breakfast. Pool & Gym. Your Next Trip!
O'Fallon
10.0 out of 10, Exceptional, (1 review)
"We needed a place to stay near to events in Lake St. Louis. This was perfect for us. Quiet. Easy access. Nice to have a small kitchenette area, shower/tub, and big fridge. "
United States
Shawna P.
$156 nightly
The price is $180
Jul 1 - Jul 2
Total with taxes and fees
King Suite. Free Breakfast. Pool & Gym. Your Next Trip!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (79 reviews)
"Great location and beautiful place. Had a wonderful time. "
United States
Ernest R.
$240 nightly
The price is $257
Jun 30 - Jul 1
Total with taxes and fees
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
$265 nightly
The price is $292
Jul 6 - Jul 7
Total with taxes and fees
The Driftwood Den | Boho-Inspired 2-Bedroom

Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
$141 nightly
The price is $162
Jul 1 - Jul 2
Total with taxes and fees
Great for Business Travelers! Pool + Gym

Walk to St. Charles Entertainment

Walk to St. Charles Entertainment
Saint Charles
9.0 out of 10, Wonderful, (10 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
$275 nightly
The price is $302
Jul 5 - Jul 6
Total with taxes and fees
Walk to St. Charles Entertainment

Spacious Townhome Retreat

Spacious Townhome Retreat
O Fallon
10.0 out of 10, Exceptional, (11 reviews)
"Great quiet neighborhood close to everything!"
United States
Jen D.
$340 nightly
The price is $390
Jun 30 - Jul 1
Total with taxes and fees
Spacious Townhome Retreat

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (18 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
$200 nightly
The price is $221
Jun 30 - Jul 1
Total with taxes and fees
The Historic Bricks on Main

2 Bedroom Townhome Walking Distance to Streets

2 Bedroom Townhome Walking Distance to Streets
Saint Charles
9.0 out of 10, Wonderful, (19 reviews)
"We were located in a nice community and very close to the "The Streets" entertainment area (2 min away), Old town St. Charles (6 min away) and 15 minutes from the airport. The owner was very helpful and answered all my questions. Check this place out!"
United States
William D.
$254 nightly
The price is $279
Jul 2 - Jul 3
Total with taxes and fees
2 Bedroom Townhome Walking Distance to Streets

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (2 reviews)
"Excellent"
United States
Scott N.
$252 nightly
The price is $283
Jun 30 - Jul 1
Total with taxes and fees
6th street 101 - Walk to Main St

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (21 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
$212 nightly
The price is $234
Jul 1 - Jul 2
Total with taxes and fees
Charming Duplex on Main

Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (8 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
$281 nightly
The price is $301
Jul 23 - Jul 24
Total with taxes and fees
Cottage on Main st- Low Cleaning Fee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles County Hotel Reviews

Find out more about St. Charles County

Discover your perfect St. Charles County vacation rental with Expedia

How many vacation rentals are available in St. Charles County?


Expedia has plenty of vacation rentals to choose from in and around  St. Charles County, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in St. Charles County?


The selection of St. Charles County vacation rentals we have selected for you start as low as $96 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in St. Charles County?


Vacation rentals in St. Charles County come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of St. Charles County vacation rentals to suit everyone. 


Why should I choose a vacation rental in St. Charles County?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A St. Charles County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in St. Charles County?


Find vacation rentals in St. Charles County by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in St. Charles County.  


What amenities are available in a vacation rental in St. Charles County?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in St. Charles County vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in St. Charles County?   


Everytime is a great time to head to St. Charles County! Staying in a St. Charles County vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in St. Charles County. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect St. Charles County vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in St. Charles County, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your St. Charles County vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.