Title: Top Independent in Hannibal, MO - Expedia.com [Hannibal Travel Guide](https://expedia.com/Hannibal.dx6068)[Hotels in Hannibal](https://expedia.com/Hannibal-Hotels.d6068.Travel-Guide-Hotels)[Vacation Rentals in Hannibal](https://expedia.com/Hannibal-Vacation-Rentals.d6068.Travel-Guide-VacationRentals)[Flights to Hannibal](https://expedia.com/Cheap-Flights-To-Hannibal.d6068.Travel-Guide-Flights)[Things to do in Hannibal](https://expedia.com/Things-To-Do-In-Hannibal.d6068.Travel-Guide-Activities)[Car Rentals in Hannibal](https://expedia.com/Car-Rentals-In-Hannibal.d6068.Car-Rental-Guide)[Hannibal Vacation Packages](https://expedia.com/Hannibal.d6068.Destination-Travel-Guides) ![If you're interested in literature/famous American authors, this might be the place for you! There are so many white sculptures of Twain it's unreal.](https://images.trvl-media.com/place/6068/c22075d3-cbe0-4b86-8545-88da9f1986ea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Daydreams and Discoveries ![](https://images.trvl-media.com/place/6068/c22075d3-cbe0-4b86-8545-88da9f1986ea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 8 - Mar 9](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-08&endDate=2026-03-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 9 - Mar 10](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-09&endDate=2026-03-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FHannibal-Hotels-Independent.0-0-d6068--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FHannibal-Hotels-Independent.0-0-d6068--bIndependent.Travel-Guide-Filter-Hotels) ## Top Hannibal Hotel Reviews ![Howard Johnson BY Wyndham Hannibal](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/6002c086_y.jpg) ### Howard Johnson BY Wyndham Hannibal 6/10 Okay "Smoke detector hanging from ceiling. Dog poop all iver the rocks outside the room. People smoking and load right outside the room." [](https://expedia.com/Hannibal-Hotels-Howard-Johnson-BY-Wyndham-Hannibal.h76266570.Hotel-Information) ![Sleep Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/863ee254_y.jpg) ### Sleep Inn & Suites Hannibal West 10/10 Excellent "We were there for just one night. Our room was very clean and pleasing to the eye. We did not use any other amenities. The lobby was very clean with seating for visiting. The staff were very friendly and helpful. The serviced a wonderful variety of breakfast items. They even used real dishes not paper. " [](https://expedia.com/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Motel 6 Hannibal, MO](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f348d54f_y.jpg) ### Motel 6 Hannibal, MO 10/10 Excellent "Great stay with no issues at all." [](https://expedia.com/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ![Quality Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/4e0fe2c3_y.jpg) ### Quality Inn & Suites Hannibal West 8/10 Good "This hotel had a hot tub; free breakfast and it accepted dog(s). " [](https://expedia.com/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Best Western On The River](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/d6669a71_y.jpg) ### Best Western On The River 8/10 Good "The pool & hot tub closed at 9pm, so we were not able to use them. That was quite disappointing. The breakfast was good. Room was clean and beds were comfortable. " [](https://expedia.com/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Super 8 by Wyndham Hannibal](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/84f5eec7_y.jpg) ### Super 8 by Wyndham Hannibal 6/10 Okay " Pool closed " [](https://expedia.com/Hannibal-Hotels-Super-8-By-Wyndham-Hannibal.h459674.Hotel-Information) ![Days Inn by Wyndham Hannibal](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/a819ab14_y.jpg) ### Days Inn by Wyndham Hannibal 8/10 Good "The room was clean. The staff were courteous. Breakfast was poor. " [](https://expedia.com/Hannibal-Hotels-Days-Inn-By-Wyndham-Hannibal.h12968.Hotel-Information) ![Comfort Inn & Suites - Hannibal](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/3aa4b816_y.jpg) ### Comfort Inn & Suites - Hannibal 10/10 Excellent "Clean room. Good location. Comfortable bed. " [](https://expedia.com/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ![The Library, a 1-bedroom apartment in Hannibal awaits your visit.](https://images.trvl-media.com/lodging/125000000/124970000/124966700/124966621/e03bd3e6_y.jpg) ### The Library, a 1-bedroom apartment in Hannibal awaits your visit. 10/10 Excellent "Super cute place with great space and a well-stocked kitchen and bathroom. I only stayed one night and didn't have time to explore, but the town looked fun with neat shops and everything you'd expect in a small heritage town. I would definitely stay here again." [](https://expedia.com/Hannibal-Hotels-The-Library.h124966621.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Rockcliffe Mansion ](https://www.expedia.com/Rockcliffe-Mansion-Hotels.0-l553248621532649035-0.Travel-Guide-Filter-Hotels) - [Hotels near Sodalis Nature Preserve ](https://www.expedia.com/Sodalis-Nature-Preserve-Hotels.0-l553248635974883083-0.Travel-Guide-Filter-Hotels) - [Hotels near Molly Brown Museum and Home ](https://www.expedia.com/Molly-Brown-Museum-And-Home-Hotels.0-l553248621561876926-0.Travel-Guide-Filter-Hotels) - [Hotels near Jim's Journey: The Huck Finn Freedom Center ](https://www.expedia.com/Jims-Journey-The-Huck-Finn-Freedom-Center-Hotels.0-l553248621561876935-0.Travel-Guide-Filter-Hotels) - [Hotels near Big River Train Town ](https://www.expedia.com/Big-River-Train-Town-Hotels.0-l553248621561876937-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain Boyhood Home and Museum ](https://www.expedia.com/Mark-Twain-Boyhood-Home-And-Museum-Hotels.0-l6092645-0.Travel-Guide-Filter-Hotels) - [Hotels near Bluff City Theater ](https://www.expedia.com/Bluff-City-Theater-Hotels.0-l553248621561876932-0.Travel-Guide-Filter-Hotels) - [Hotels near Planters Barn Theater ](https://www.expedia.com/Planters-Barn-Theater-Hotels.0-l553248621532649040-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain Memorial Lighthouse ](https://www.expedia.com/Mark-Twain-Memorial-Lighthouse-Hotels.0-l6092647-0.Travel-Guide-Filter-Hotels) - [Hotels near Lovers Leap ](https://www.expedia.com/Lovers-Leap-Hotels.0-l553248621561876927-0.Travel-Guide-Filter-Hotels) - [Hotels near Sawyer's Creek Fun Park ](https://www.expedia.com/Sawyers-Creek-Fun-Park-Hotels.0-l553248621561876929-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain Cave and Cameron Cave ](https://www.expedia.com/Mark-Twain-Cave-And-Cameron-Cave-Hotels.0-l553248621532649037-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain Cave ](https://www.expedia.com/Mark-Twain-Cave-Hotels.0-l6092649-0.Travel-Guide-Filter-Hotels) - [New London Hotels ](https://www.expedia.com/New-London-Hotels.d3000445314.Travel-Guide-Hotels) - [Cabin Rentals in New London ](https://www.expedia.com/New-London-Cabins.d3000445314-aaCabins.Travel-Guide-Accommodation) - [B&B in New London ](https://www.expedia.com/New-London-Bed-And-Breakfast.d3000445314-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Palmyra Hotels ](https://www.expedia.com/Palmyra-Hotels.d183484.Travel-Guide-Hotels) - [Guest Houses in Palmyra ](https://www.expedia.com/Palmyra-Guest-Houses.d183484-aaGuestHouses.Travel-Guide-Accommodation) - [B&B in Palmyra ](https://www.expedia.com/Palmyra-Bed-And-Breakfast.d183484-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Palmyra ](https://www.expedia.com/Palmyra-Hotels-Pet-Friendly-Hotel.0-0-d183484-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Palmyra ](https://www.expedia.com/Palmyra-Cabins.d183484-aaCabins.Travel-Guide-Accommodation) - [Hotels near Gardner House Museum ](https://www.expedia.com/Gardner-House-Museum-Hotels.0-l553248621532649025-0.Travel-Guide-Filter-Hotels) - [Frankford Hotels ](https://www.expedia.com/Frankford-Hotels.d3000444895.Travel-Guide-Hotels) - [Motels in Frankford ](https://www.expedia.com/Frankford-Motels.d3000444895-aaMotels.Travel-Guide-Accommodation) - [3 Star Hotels in Frankford ](https://www.expedia.com/3Star-Frankford-Hotels.s30-0-d3000444895.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Frankford ](https://www.expedia.com/4Star-Frankford-Hotels.s40-0-d3000444895.Travel-Guide-Filter-Hotels) - [West Quincy Hotels ](https://www.expedia.com/West-Quincy-Hotels.d553248635974906355.Travel-Guide-Hotels) - [Taylor Hotels ](https://www.expedia.com/Taylor-Hotels.d3000445518.Travel-Guide-Hotels) - [5 Star Hotels in Taylor ](https://www.expedia.com/5Star-Taylor-Hotels.s50-0-d3000445518.Travel-Guide-Filter-Hotels) - [Monroe City Hotels ](https://www.expedia.com/Monroe-City-Hotels.d8694.Travel-Guide-Hotels) - [Cabin Rentals in Monroe City ](https://www.expedia.com/Monroe-City-Cabins.d8694-aaCabins.Travel-Guide-Accommodation) - [Condo Rentals in Monroe City ](https://www.expedia.com/Monroe-City-Condos.d8694-aaCondos.Travel-Guide-Accommodation) - [Motels in Monroe City ](https://www.expedia.com/Monroe-City-Motels.d8694-aaMotels.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Monroe City ](https://www.expedia.com/Monroe-City-Hotels-Pet-Friendly-Hotel.0-0-d8694-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [B&B in Monroe City ](https://www.expedia.com/Monroe-City-Bed-And-Breakfast.d8694-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Monroe City ](https://www.expedia.com/Monroe-City-Hotels-Cheap-Hotels.0-0-d8694-tCheapHotels.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Monroe City ](https://www.expedia.com/3Star-Monroe-City-Hotels.s30-0-d8694.Travel-Guide-Filter-Hotels) - [Maywood Hotels ](https://www.expedia.com/Maywood-Hotels.d6320335.Travel-Guide-Hotels) - [Hotels near Wakonda State Park ](https://www.expedia.com/Wakonda-State-Park-Hotels.0-l553248621532649028-0.Travel-Guide-Filter-Hotels) - [Perry Hotels ](https://www.expedia.com/Perry-Hotels.d6288740.Travel-Guide-Hotels) - [Cabin Rentals in Perry ](https://www.expedia.com/Perry-Cabins.d6288740-aaCabins.Travel-Guide-Accommodation) - [B&B in Perry ](https://www.expedia.com/Perry-Bed-And-Breakfast.d6288740-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Hot Tubs in Perry ](https://www.expedia.com/Perry-Hotels-Hotels-With-Hot-Tubs.0-0-d6288740-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels on the Lake in Perry ](https://www.expedia.com/Perry-Hotels-Lakefront-Hotels.0-0-d6288740-tLakefrontHotels.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Perry ](https://www.expedia.com/Perry-Hotels-Wedding-Hotels.0-0-d6288740-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Perry ](https://www.expedia.com/Perry-Hotels-Spa-Hotel.0-0-d6288740-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain Casino ](https://www.expedia.com/Mark-Twain-Casino-Hotels.0-l553248621561876918-0.Travel-Guide-Filter-Hotels) - [La Grange Hotels ](https://www.expedia.com/La-Grange-Hotels.d6354592.Travel-Guide-Hotels) - [Flights from New London ](https://www.expedia.com/lp/flights/3000445314/flights-from-new-london) - [Flights to New London ](https://www.expedia.com/Cheap-Flights-To-New-London.d3000445314.Travel-Guide-Flights) - [Flights to Palmyra ](https://www.expedia.com/Cheap-Flights-To-Palmyra.d183484.Travel-Guide-Flights) - [Flights from Palmyra ](https://www.expedia.com/lp/flights/183484/flights-from-palmyra) - [Flights to Frankford ](https://www.expedia.com/Cheap-Flights-To-Frankford.d3000444895.Travel-Guide-Flights) - [Flights from Frankford ](https://www.expedia.com/lp/flights/3000444895/flights-from-frankford) - [Flights to Taylor ](https://www.expedia.com/Cheap-Flights-To-Taylor.d3000445518.Travel-Guide-Flights) - [Flights to Monroe City ](https://www.expedia.com/Cheap-Flights-To-Monroe-City.d8694.Travel-Guide-Flights) - [Flights from Monroe City ](https://www.expedia.com/lp/flights/8694/flights-from-monroe-city) - [Flights from Maywood ](https://www.expedia.com/lp/flights/6320335/flights-from-maywood) - [Flights to Perry ](https://www.expedia.com/Cheap-Flights-To-Perry.d6288740.Travel-Guide-Flights) - [Flights from La Grange ](https://www.expedia.com/lp/flights/6354592/flights-from-la-grange) - [Rockcliffe Mansion ](https://www.expedia.com/Rockcliffe-Mansion-Hannibal.d553248621532649035.Vacation-Attraction) - [Sodalis Nature Preserve ](https://www.expedia.com/Sodalis-Nature-Preserve-Hannibal.d553248635974883083.Vacation-Attraction) - [Molly Brown Museum and Home ](https://www.expedia.com/Molly-Brown-Museum-And-Home-Hannibal.d553248621561876926.Vacation-Attraction) - [Jim's Journey: The Huck Finn Freedom Center ](https://www.expedia.com/Jims-Journey-The-Huck-Finn-Freedom-Center-Hannibal.d553248621561876935.Vacation-Attraction) - [Big River Train Town ](https://www.expedia.com/Big-River-Train-Town-Hannibal.d553248621561876937.Vacation-Attraction) - [Mark Twain Boyhood Home and Museum ](https://www.expedia.com/Mark-Twain-Boyhood-Home-And-Museum-Hannibal.d6092645.Vacation-Attraction) - [Mark Twain Memorial Lighthouse ](https://www.expedia.com/Mark-Twain-Memorial-Lighthouse-Hannibal.d6092647.Vacation-Attraction) - [Bluff City Theater ](https://www.expedia.com/Bluff-City-Theater-Hannibal.d553248621561876932.Vacation-Attraction) - [Planters Barn Theater ](https://www.expedia.com/Planters-Barn-Theater-Hannibal.d553248621532649040.Vacation-Attraction) - [Lovers Leap ](https://www.expedia.com/Lovers-Leap-Hannibal.d553248621561876927.Vacation-Attraction) - [Sawyer's Creek Fun Park ](https://www.expedia.com/Sawyers-Creek-Fun-Park-Hannibal.d553248621561876929.Vacation-Attraction) - [Mark Twain Cave and Cameron Cave ](https://www.expedia.com/Mark-Twain-Cave-And-Cameron-Cave-Hannibal.d553248621532649037.Vacation-Attraction) - [Mark Twain Cave ](https://www.expedia.com/Mark-Twain-Cave-Hannibal.d6092649.Vacation-Attraction) - [Visit New London ](https://www.expedia.com/New-London.dx3000445314) - [Visit Palmyra ](https://www.expedia.com/Palmyra.dx183484) - [Gardner House Museum ](https://www.expedia.com/Gardner-House-Museum-Palmyra.d553248621532649025.Vacation-Attraction) - [Visit Saverton ](https://www.expedia.com/Saverton.dx3000349535) - [Visit Frankford ](https://www.expedia.com/Frankford.dx3000444895) - [Visit Taylor ](https://www.expedia.com/Taylor.dx3000445518) - [Visit Monroe City ](https://www.expedia.com/Monroe-City.dx8694) - [Visit Maywood ](https://www.expedia.com/Maywood.dx6320335) - [Perry Vacations ](https://www.expedia.com/Perry.d6288740.Destination-Travel-Guides) - [Visit Perry ](https://www.expedia.com/Perry.dx6288740) - [Mark Twain Casino ](https://www.expedia.com/Mark-Twain-Casino-La-Grange.d553248621561876918.Vacation-Attraction) - [Visit La Grange ](https://www.expedia.com/La-Grange.dx6354592) - [Car rentals near Jim's Journey: The Huck Finn Freedom Center ](https://www.expedia.com/Car-Rentals-In-Jims-Journey-The-Huck-Finn-Freedom-Center.d553248621561876935.Car-Rental-Guide) - [Car rentals near New London ](https://www.expedia.com/Car-Rentals-In-New-London.d3000445314.Car-Rental-Guide) - [Car rentals near Rensselaer ](https://www.expedia.com/Car-Rentals-In-Rensselaer.d553248634983403977.Car-Rental-Guide) - [Car rentals near Palmyra ](https://www.expedia.com/Car-Rentals-In-Palmyra.d183484.Car-Rental-Guide) - [Car rentals near Saverton ](https://www.expedia.com/Car-Rentals-In-Saverton.d3000349535.Car-Rental-Guide) - [Car rentals near Frankford ](https://www.expedia.com/Car-Rentals-In-Frankford.d3000444895.Car-Rental-Guide) - [Car rentals near West Quincy ](https://www.expedia.com/Car-Rentals-In-West-Quincy.d553248635974906355.Car-Rental-Guide) - [Car rentals near Taylor ](https://www.expedia.com/Car-Rentals-In-Taylor.d3000445518.Car-Rental-Guide) - [Car rentals near Monroe City ](https://www.expedia.com/Car-Rentals-In-Monroe-City.d8694.Car-Rental-Guide) - [Car rentals near Maywood ](https://www.expedia.com/Car-Rentals-In-Maywood.d6320335.Car-Rental-Guide) - [Car rentals near Perry ](https://www.expedia.com/Car-Rentals-In-Perry.d6288740.Car-Rental-Guide) - [Car rentals near La Grange ](https://www.expedia.com/Car-Rentals-In-La-Grange.d6354592.Car-Rental-Guide) - [Palmyra Vacation Rentals ](https://www.expedia.com/Palmyra-Vacation-Rentals.d183484.Travel-Guide-VacationRentals) - [Monroe City Vacation Rentals ](https://www.expedia.com/Monroe-City-Vacation-Rentals.d8694.Travel-Guide-VacationRentals) - [La Grange Vacation Rentals ](https://www.expedia.com/La-Grange-Vacation-Rentals.d6354592.Travel-Guide-VacationRentals)