Title: Top Independent in Hannibal, MO - Expedia.com [Hannibal Travel Guide](https://expedia.com/Hannibal.dx6068)[Hotels in Hannibal](https://expedia.com/Hannibal-Hotels.d6068.Travel-Guide-Hotels)[Vacation Rentals in Hannibal](https://expedia.com/Hannibal-Vacation-Rentals.d6068.Travel-Guide-VacationRentals)[Flights to Hannibal](https://expedia.com/Cheap-Flights-To-Hannibal.d6068.Travel-Guide-Flights)[Things to do in Hannibal](https://expedia.com/Things-To-Do-In-Hannibal.d6068.Travel-Guide-Activities)[Car Rentals in Hannibal](https://expedia.com/Car-Rentals-In-Hannibal.d6068.Car-Rental-Guide)[Hannibal Vacation Packages](https://expedia.com/Hannibal.d6068.Destination-Travel-Guides) ![If you're interested in literature/famous American authors, this might be the place for you! There are so many white sculptures of Twain it's unreal.](https://images.trvl-media.com/place/6068/c22075d3-cbe0-4b86-8545-88da9f1986ea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Daydreams and Discoveries ![](https://images.trvl-media.com/place/6068/c22075d3-cbe0-4b86-8545-88da9f1986ea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 9 - Mar 10](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-09&endDate=2026-03-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 10 - Mar 11](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6068&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FHannibal-Hotels-Independent.0-0-d6068--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FHannibal-Hotels-Independent.0-0-d6068--bIndependent.Travel-Guide-Filter-Hotels) ## Top Hannibal Hotel Reviews ![Sleep Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/863ee254_y.jpg) ### Sleep Inn & Suites Hannibal West 10/10 Excellent "We didn't get a chance to use the gym or pool due to our short stay. They looked very well kept." [](https://expedia.com/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Best Western On The River](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/d6669a71_y.jpg) ### Best Western On The River 10/10 Excellent "Wonderful stay.Will definitely be staying here again and will recommend to all going to Hannibal." [](https://expedia.com/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Howard Johnson BY Wyndham Hannibal](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/6002c086_y.jpg) ### Howard Johnson BY Wyndham Hannibal 6/10 Okay "Smoke detector hanging from ceiling. Dog poop all iver the rocks outside the room. People smoking and load right outside the room." [](https://expedia.com/Hannibal-Hotels-Howard-Johnson-BY-Wyndham-Hannibal.h76266570.Hotel-Information) ![Motel 6 Hannibal, MO](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f348d54f_y.jpg) ### Motel 6 Hannibal, MO 10/10 Excellent "Great stay with no issues at all." [](https://expedia.com/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ![Quality Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/4e0fe2c3_y.jpg) ### Quality Inn & Suites Hannibal West 8/10 Good "This hotel had a hot tub; free breakfast and it accepted dog(s). " [](https://expedia.com/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Super 8 by Wyndham Hannibal](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/84f5eec7_y.jpg) ### Super 8 by Wyndham Hannibal 6/10 Okay " Pool closed " [](https://expedia.com/Hannibal-Hotels-Super-8-By-Wyndham-Hannibal.h459674.Hotel-Information) ![Days Inn by Wyndham Hannibal](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/a819ab14_y.jpg) ### Days Inn by Wyndham Hannibal 8/10 Good "The room was clean. The staff were courteous. Breakfast was poor. " [](https://expedia.com/Hannibal-Hotels-Days-Inn-By-Wyndham-Hannibal.h12968.Hotel-Information) ![Comfort Inn & Suites - Hannibal](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/3aa4b816_y.jpg) ### Comfort Inn & Suites - Hannibal 10/10 Excellent "Clean room. Good location. Comfortable bed. " [](https://expedia.com/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ![Garden House Bed and Breakfast](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/dca4ff6b_y.jpg) ### Garden House Bed and Breakfast 2/10 Terrible "They voided our stay, cacelled and told us they dont take same day reservations" [](https://expedia.com/Hannibal-Hotels-Garden-House-Bed-And-Breakfast.h103844330.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Rockcliffe Mansion ](https://www.expedia.com/Rockcliffe-Mansion-Hotels.0-l553248621532649035-0.Travel-Guide-Filter-Hotels) - [Hotels near Sodalis Nature Preserve ](https://www.expedia.com/Sodalis-Nature-Preserve-Hotels.0-l553248635974883083-0.Travel-Guide-Filter-Hotels) - [Hotels near Molly Brown Museum and Home ](https://www.expedia.com/Molly-Brown-Museum-And-Home-Hotels.0-l553248621561876926-0.Travel-Guide-Filter-Hotels) - [Hotels near Jim's Journey: The Huck Finn Freedom Center ](https://www.expedia.com/Jims-Journey-The-Huck-Finn-Freedom-Center-Hotels.0-l553248621561876935-0.Travel-Guide-Filter-Hotels) - 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