Louisiana Vacations from $240

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Louisiana Vacation

The lively city of Louisiana is calling. Discover its highlights and hidden gems with a Louisiana vacation package that's tailored to you. During your trip to Louisiana, set aside some time for sightseeing. An excellent place to begin is The Eagles Nest Winery. Whatever your travel plans or budget, organizing a tailored Louisiana vacation is easy with Expedia.

The Latest Louisiana vacation packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
The Wildwood Hotel
Hampton Inn By Hilton St Louis Airport
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Crowne Plaza St. Louis Airport by IHG
Don't see what you're looking for?
See all available trips from Columbus to Louisiana
View all trips

Louisiana Hotel Deals

River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St, Louisiana, MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Nov 9 to Nov 10
$97 total
Nov 9 - Nov 10
Total with taxes and fees
8.8/10 Excellent! (350 reviews)
Room was very clean and fresh smelling. We had stayed before (July 2025) and our room smelled old and damp. This time was MUCH better. Staff was very pleasant. We will use River's Edge again. Thank you so much!

Reviewed on Oct 13, 2025

River's Edge Motel
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St, Louisiana, MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $110 total per night from Nov 11 to Nov 12
$110 total
Nov 11 - Nov 12
Total with taxes and fees
9.2/10 Wonderful! (18 reviews)
Clean. Big bathroom. Bed squeaky. Walkable to river and some eating spots. It is full of history and the building was renovated beautifully. There were no common spaces to sit, it would be nice to have that outside of room 11. We would return.

Reviewed on Oct 12, 2025

The Eagles Nest Inn
The Yellow Rose Historic Home

The Yellow Rose Historic Home

Louisiana
$336 nightly
The price is $346 total per night from Nov 30 to Dec 1
$346 total
Nov 30 - Dec 1
Total with taxes and fees
9.8/10 Exceptional! (11 reviews)
Overall we had a great visit. Just trying to be honest with the review. There are a ton of stains on the back stairway carpet that look like they could be mold. The bathrooms weren't particularly clean. Wallpaper was peeling in places. It could use a touch up for sure, but we did stay comfortably ...

Reviewed on Oct 8, 2025

The Yellow Rose Historic Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Louisiana Vacation Packages

Things to do near Louisiana

Louisiana, Missouri, is perfect for outdoor enthusiasts and romantic getaways, offering scenic beauty and a range of activities. Visitors can enjoy boat tours, explore local museums, and partake in exciting day tours. The area also hosts lively festivals that provide unforgettable experiences. With recreational areas and trail access, there's something for everyone to appreciate in this charming destination.

Shopping

In Louisiana, you'll find charming local shops along Main Street, offering unique gifts and souvenirs. If you're up for a drive, visit the nearby Shopping Plaza in Hannibal, featuring a variety of retail stores and dining options for a full day of shopping.

Recreation

At Old Orchard Country Club, enjoy a round of golf surrounded by beautiful landscapes, perfect for relaxation and outdoor enjoyment. Experience the charm of Planters Barn Theater and Bluff City Theater, where you can immerse yourself in captivating performances that blend culture, romance, and family entertainment.

Adventure

Explore the scenic Mississippi River through kayaking or paddleboarding, hike the nearby Mark Twain State Park for stunning views, and visit local historical sites. Enjoy fishing, birdwatching, or biking along the riverfront trails, immersing yourself in Louisiana's natural beauty and rich culture.

Nightlife

In Louisiana, Missouri, enjoy a lively evening at the charming Old Bluebird Café for great food and music. For a relaxed vibe, visit the Riverfront Bar & Grill, where you can unwind with friends while enjoying scenic views of the Mississippi River.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Louisiana

Located along the Mississippi River, Louisiana, Missouri, is an ideal destination for outdoor enthusiasts and those seeking a romantic getaway. Visitors can explore scenic caves, enjoy the beauty of urban parks, or take in the river views. The area offers a blend of cultural experiences and family-friendly activities, making it a memorable spot for all types of travelers looking for an unforgettable escape.

  • Mississippi River: Experience the beauty of the iconic Mississippi River, located 9 miles from Louisiana. Enjoy stunning scenery and outdoor activities along its banks, perfect for a day of relaxation or adventure.
  • Clarksville State Game Refuge: Just 8 miles away, this reserve offers a family-friendly atmosphere where you can spot wildlife and enjoy excursions in nature. It's a great spot for relaxation and connecting with friendly locals.
  • Clarksville Riverfront Park: Situated 9 miles from Louisiana, this urban park provides an engaging blend of outdoor activities and city vibes. Perfect for families, you can stroll, picnic, and enjoy the scenic river views.

Best time to go to Louisiana

The best time to visit Louisiana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Louisiana falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Louisiana falls in January, visitor numbers are slightly low and weather is mostly with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January28.6°F (-1.9°C)Light RainMostlySlightly LowSlightly Low
February31.6°F (-0.2°C)Light RainMostly SunnyAverageAverage
March44.1°F (6.7°C)Light RainMostly SunnyAverageAverage
April53.8°F (12.1°C)Light RainMostly SunnySlightly HighAverage
May64.0°F (17.8°C)Light RainMostly SunnyAverageSlightly High
June73.8°F (23.2°C)Light RainMostly SunnyAverageSlightly High
July76.6°F (24.8°C)Light RainMostly SunnySlightly HighSlightly High
August75.0°F (23.9°C)Light RainMostly SunnyAverageAverage
September69.1°F (20.6°C)Light RainMostly SunnySlightly HighAverage
October56.3°F (13.5°C)Light RainMostly SunnyAverageAverage
November44.1°F (6.7°C)Light RainMostly SunnySlightly LowSlightly Low
December35.1°F (1.7°C)Light RainMostly SunnySlightly LowSlightly Low

Tips to save on your trip to Louisiana

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling during the off-peak season (typically November to January) for more affordable package holidays to Louisiana.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Louisiana Essential Information

Language
English
Currency
U.S dollars
Population
3,300
Max Temp Winter
35ºF
Max Temp Summer
85ºF
Top Sights
The Eagles Nest Winery and Clarksville Riverfront Park

More vacations you might like

Frequently asked questions

How much does a Louisiana vacation package cost?
Offering excellent value package deals from $240 on Expedia, you'll be pleasantly surprised at how much a vacation to Louisiana costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Louisiana?
You can usually find reduced prices and better availability in January, February and March. Explore our cheap Louisiana vacation packages and you could score some great off-season discounts.
How many days is enough for Louisiana?
Generally, a handful of days is enough to explore the top sights during your Louisiana vacation. However, if you prefer to have some time to chill out or go on day tours, think about extending your itinerary.
How to find the best Louisiana package deals?
Use Expedia's handy filters to help you find some terrific Louisiana package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or look for Louisiana package deals in the low season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
Is it cheaper to book a Louisiana vacation as a package?
You can enjoy significant savings on your Louisiana retreat by booking a customized vacation package. Check the "Package" heading, then select your destination and travel dates to see some great flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Louisiana?
If you've got your Louisiana travel dates finalized, book early to snap up some terrific deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for quick escapes.
Does Expedia offer Book Now, Pay Later Louisiana vacation packages?
If you're like us, you love going away but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the cost of your Louisiana vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.